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Emerging Technologies in Markets for the Early Detection of Head and Neck Cancer

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Early Detection and Treatment of Head & Neck Cancers

Abstract

Head and neck cancer (HNC) is one of the most common types of cancers accounting for 5% of total cancer cases worldwide. The proportion of HNC among malignancies is of much higher prominence in some world regions (e.g., up to 30% in Indo-Asia) as 70% of these cancers are induced by lifestyle habits. Risk factors have been identified such as alcohol, tobacco, smoking, and viral infections (e.g., HPV and EBV). While HNC is often curable when detected early, most patients present with late-stage cancer with regional nodal metastases, and up to 10% of them have distal metastases at the time of the first diagnosis. To date, no national screening programs for HNC have been implemented in the general population nor in high-risk groups. Timely and ultra-sensitive detection is also essential in patients with late-stage HNC to monitor disease recurrence and to assure locoregional control with an overall survival benefit. This chapter provides an overview of technologies that, along with appropriate biomarkers, are poised to revolutionize the early detection of HNC in the coming years.

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Authors and Affiliations

  1. Exosomics, S.p.A, Siena, Italy

    Laura Bianciardi, Claudio Corallo, Mattia Criscuoli, Diogo Fortunato, Natasa Zarovni & Davide Zocco

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  1. Laura Bianciardi
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  2. Claudio Corallo
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  3. Mattia Criscuoli
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  4. Diogo Fortunato
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  5. Natasa Zarovni
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  6. Davide Zocco
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Correspondence to Davide Zocco .

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  1. Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA, USA

    Rami El Assal

  2. Division of Plastic & Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA

    Dyani Gaudilliere

  3. Department of Oral and Maxillofacial Surgery, University of California, San Francisco, San Francisco, CA, USA

    Stephen Thaddeus Connelly

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Bianciardi, L., Corallo, C., Criscuoli, M., Fortunato, D., Zarovni, N., Zocco, D. (2021). Emerging Technologies in Markets for the Early Detection of Head and Neck Cancer. In: El Assal, R., Gaudilliere, D., Connelly, S.T. (eds) Early Detection and Treatment of Head & Neck Cancers. Springer, Cham. https://doi.org/10.1007/978-3-030-69859-1_2

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