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Designing Novel Synthetic Grafts for Large Bone Defects: Experimental and Numerical Studies

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Experiments and Simulations in Advanced Manufacturing

Part of the book series: Materials Forming, Machining and Tribology ((MFMT))

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Abstract

Large bone defects, usually associated to victims of natural disasters, wars and severe accidents, represent a major clinical problem. The search for an effective and efficient treatment is a key area of research. Our group is exploring a novel and fully automatic approach to produce synthetic grafts anatomically designed to fit on the defect site and able to promote tissue regeneration.

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Acknowledgements

This project has been supported by the University of Manchester and the Engineering and Physical Sciences Research Council (EPSRC) of the UK, the Global Challenges Research Fund (CRF), grant number EP/R01513/1.

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Authors and Affiliations

  1. School of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester, M13 9PL, UK

    Evangelos Daskalakis,Ā Zhanyan Xu,Ā Abdalla M. Omar,Ā Fengyuan Liu,Ā Glen Cooper,Ā Andrew WeightmanĀ &Ā Paulo Bartolo

  2. Faculty of Engineering and Natural Sciences, Sabanci University, Orhanli-Tuzla, Istanbul, 34956, Turkey

    Anil A. Acar,Ā Ali FallahĀ &Ā Bahattin KoƧ

  3. School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, PO1 2DT, UK

    Gordon Blunn

Authors
  1. Evangelos Daskalakis
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  2. Zhanyan Xu
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  3. Abdalla M. Omar
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  4. Fengyuan Liu
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  5. Anil A. Acar
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  6. Ali Fallah
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  7. Glen Cooper
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  8. Andrew Weightman
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  9. Gordon Blunn
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  10. Bahattin KoƧ
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  11. Paulo Bartolo
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Corresponding author

Correspondence to Paulo Bartolo .

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Editors and Affiliations

  1. Department of Product and Systems Design Engineering, University of Western Macedonia, Kila Kozani, Greece

    Panagiotis Kyratsis

  2. Department of Mechanical Engineering, University of Aveiro, Aveiro, Portugal

    J. Paulo Davim

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Daskalakis, E. et al. (2021). Designing Novel Synthetic Grafts for Large Bone Defects: Experimental and Numerical Studies. In: Kyratsis, P., Davim, J.P. (eds) Experiments and Simulations in Advanced Manufacturing. Materials Forming, Machining and Tribology. Springer, Cham. https://doi.org/10.1007/978-3-030-69472-2_4

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  • DOI: https://doi.org/10.1007/978-3-030-69472-2_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-69471-5

  • Online ISBN: 978-3-030-69472-2

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