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Unusual Dermatophytosis Presentations and New Emerging Dermatophytes Species

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Dermatophytes and Dermatophytoses

Abstract

Dermatophytes are causing superficial mycosis in animals and humans. Depending on the geophilic, zoophilic or anthropophilic origin of the fungus but also on the immunological status of the patient, symptomatology can widely differ. Nevertheless, each species is currently associated with typical clinical manifestations, even if atypical localizations and/or clinical pictures are sometimes also reported. Diagnostic tools applied to species identification have been changing since the last two decades with the more frequent use of molecular methods currently considered nowadays as reference methods for species identification. It becomes obvious that the algorithm used for the distinction of closely related species needs to combine phenotypic and genomic methods. All these different points are discussed and the most recent novel species causing or involved in human dermatophytosis are reported.

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References

  1. de Hoog GS, Dukik K, Monod M, Packeu A, Stubbe D, Hendrickx M, et al. Toward a novel multilocus phylogenetic taxonomy for the dermatophytes. Mycopathologia. 2017;182(1–2):5–31.

    Article  PubMed  Google Scholar 

  2. Seebacher C, Bouchara JP, Mignon B. Updates on the epidemiology of dermatophyte infections. Mycopathologia. 2008;166(5–6):335–52.

    Article  PubMed  Google Scholar 

  3. Hayette M-P, Sacheli R. Dermatophytosis, trends in epidemiology and diagnostic approach. Curr Fungal Infect Rep. 2015;9(3):164–79.

    Article  Google Scholar 

  4. Nenoff P, Uhrlass S, Kruger C, Erhard M, Hipler UC, Seyfarth F, et al. Trichophyton species of Arthroderma benhamiae—a new infectious agent in dermatology. J Dtsch Dermatol Ges. 2014;12(7):571–81.

    PubMed  Google Scholar 

  5. Rippon JW. The changing epidemiology and emerging patterns of dermatophyte species. Curr Top Med Mycol. 1985;1:208–34.

    Article  CAS  PubMed  Google Scholar 

  6. Hay RJ. Tinea capitis: current status. Mycopathologia. 2017;182(1–2):87–93.

    Article  CAS  PubMed  Google Scholar 

  7. Swinne D, Watelle M, Suetens C, Mertens K, Fonteyne PA, Nolard N. A one-year survey of candidemia in Belgium in 2002. Epidemiol Infect. 2004;132(6):1175–80.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Gits-Muselli M, Benderdouche M, Hamane S, Mingui A, Feuilhade de Chauvin M, Guigue N, et al. Continuous increase of Trichophyton tonsurans as a cause of tinea capitis in the urban area of Paris, France: a 5-year-long study. Med Mycol. 2017;55(5):476–84.

    CAS  PubMed  Google Scholar 

  9. Aneke CI, Otranto D, Cafarchia C. Therapy and antifungal susceptibility profile of Microsporum canis. J Fungi (Basel). 2018;4(3):107.

    Article  CAS  Google Scholar 

  10. Nenoff P, Kruger C, Ginter-Hanselmayer G, Tietz HJ. Mycology—an update. Part 1: dermatomycoses: causative agents, epidemiology and pathogenesis. J Dtsch Dermatol Ges. 2014;12(3):188–209; quiz 10, 188–211; quiz 2.

    PubMed  Google Scholar 

  11. García-Martos P, Ruiz-Aragón J, García-Agudo L, Linares M. Dermatophytoses due to Microsporum gypseum: report of eight cases and literature review. Rev Iberoam Micol. 2004;21(3):147–9.

    PubMed  Google Scholar 

  12. Hayette MP, Seidel L, Adjetey C, Darfouf R, Wery M, Boreux R, et al. Clinical evaluation of the DermaGenius® Nail real-time PCR assay for the detection of dermatophytes and Candida albicans in nails. Med Mycol. 2019;57(3):277–83.

    Google Scholar 

  13. Kupsch C, Ohst T, Pankewitz F, Nenoff P, Uhrlass S, Winter I, et al. The agony of choice in dermatophyte diagnostics-performance of different molecular tests and culture in the detection of Trichophyton rubrum and Trichophyton interdigitale. Clin Microbiol Infect. 2016;22(8):735.e11–7.

    Article  CAS  Google Scholar 

  14. Verrier J, Monod M. Diagnosis of dermatophytosis using molecular biology. Mycopathologia. 2017;182(1–2):193–202.

    Article  CAS  PubMed  Google Scholar 

  15. Brasch J, Beck-Jendroschek V, Voss K, Yurkov A, Graser Y. Arthroderma chiloniense sp. nov. isolated from human stratum corneum: description of a new Arthroderma species. Mycoses. 2019;62(1):73–80.

    Article  CAS  PubMed  Google Scholar 

  16. Borman AM, Szekely A, Fraser M, Lovegrove S, Johnson EM. A novel dermatophyte relative, Nannizzia perplicata sp. nov., isolated from a case of tinea corporis in the United Kingdom. Med Mycol. 2018. https://doi.org/10.1093/mmy/myy099.

  17. Hubka V, Dobiasova S, Dobias R, Kolarik M. Microsporum aenigmaticum sp. nov. from M. gypseum complex, isolated as a cause of tinea corporis. Med Mycol. 2014;52(4):387–96.

    Google Scholar 

  18. Hubka V, Nissen CV, Jensen RH, Arendrup MC, Cmokova A, Kubatova A, et al. Discovery of a sexual stage in Trichophyton onychocola, a presumed geophilic dermatophyte isolated from toenails of patients with a history of T. rubrum onychomycosis. Med Mycol. 2015;53(8):798–809.

    Article  PubMed  Google Scholar 

  19. Choi JS, Graser Y, Walther G, Peano A, Symoens F, de Hoog S. Microsporum mirabile and its teleomorph Arthroderma mirabile, a new dermatophyte species in the M. cookei clade. Med Mycol. 2012;50(2):161–9.

    Article  PubMed  Google Scholar 

  20. Brasch J, Gräser Y. Trichophyton eboreum sp. nov. isolated from human skin. J Clin Microbiol. 2005;43(10):5230–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Campbell CK, Borman AM, Linton CJ, Bridge PD, Johnson EM. Arthroderma olidum, sp. nov. a new addition to the Trichophyton terrestre complex. Med Mycol. 2006;44(5):451–9.

    Article  PubMed  Google Scholar 

  22. Hubka V, Cmokova A, Skorepova M, Mikula P, Kolarik M. Trichophyton onychocola sp. nov. isolated from human nail. Med Mycol. 2014;52(3):285–92.

    Article  CAS  PubMed  Google Scholar 

  23. Elavarashi E, Kindo AJ, Kalyani J. Optimization of PCR-RFLP directly from the skin and nails in cases of dermatophytosis, targeting the ITS and the 18S ribosomal DNA regions. J Clin Diagn Res. 2013;7(4):646–51.

    CAS  PubMed  PubMed Central  Google Scholar 

  24. Peano A, Tizzani P, Gallo M, Molinar Min A, Rambozzi L, Meneguz P. Dermatophytosis due to Trichophyton verrucosum in a chamois (Rupicapra rupicapra). Eur J Wildl Res. 2008;54(1):153–6.

    Article  Google Scholar 

  25. Keller MC, French LE, Hofbauer GFL, Bosshard PP. Erythematous skin macules with isolation of Trichophyton eboreum—infection or colonisation? Mycoses. 2013;56(3):373–5.

    Article  PubMed  Google Scholar 

  26. Zhang ZY, Han YF, Chen WH, Liang ZQ. Phylogeny and taxonomy of three new Ctenomyces (Arthrodermataceae, Onygenales) species from China. MycoKeys. 2019;47:1–16.

    Article  CAS  Google Scholar 

  27. Rahul Sharma YS. Nannizzia graeserae sp nov, a new dermatophyte of geophilic clade isolated from vicinity of a barbershop in India. Kavaka. 2018;50:14–20.

    Google Scholar 

  28. Sitterle E, Frealle E, Foulet F, Cabaret O, Cremer G, Guillot J, et al. Trichophyton bullosum: a new zoonotic dermatophyte species. Med Mycol. 2012;50(3):305–9.

    Article  PubMed  Google Scholar 

  29. Lyskova P, Hubka V, Cmokova A, Kolarik M, Petricakova A, Dobias R. Equine dermatophytosis due to Trichophyton bullosum, a poorly known zoophilic dermatophyte masquerading as T. verrucosum. Mycopathologia. 2015;180(5–6):407–19.

    Article  PubMed  Google Scholar 

  30. Miyasato H, Yamaguchi S, Taira K, Hosokawa A, Kayo S, Sano A, et al. Tinea corporis caused by Microsporum gallinae: first clinical case in Japan. J Dermatol. 2011;38(5):473–8.

    Article  PubMed  Google Scholar 

  31. Sabou M, Boulanger N, Ganel S, Filali F, Lipsker D, Glatz I, et al. Émergence d’un dermatophyte proche de Trichophyton mentagrophytes var. erinacei et inféodé au cochon d’inde: description de sept cas diagnostiqués au CHU de Strasbourg entre novembre 2010 et octobre 2011. J Mycol Med. 2012;22(1):114.

    Article  Google Scholar 

  32. Rhee DY, Kim MS, Chang SE, Lee MW, Choi JH, Moon KC, et al. A case of tinea manuum caused by Trichophyton mentagrophytes var. erinacei: the first isolation in Korea. Mycoses. 2009;52(3):287–90.

    Article  CAS  PubMed  Google Scholar 

  33. Mochizuki T, Takeda K, Nakagawa M, Kawasaki M, Tanabe H, Ishizaki H. The first isolation in Japan of Trichophyton mentagrophytes var. erinacei causing tinea manuum. Int J Dermatol. 2005;44(9):765–8.

    Article  PubMed  Google Scholar 

  34. Lee DW, Yang JH, Choi SJ, Won CH, Chang SE, Lee MW, et al. An unusual clinical presentation of tinea faciei caused by Trichophyton mentagrophytes var. erinacei. Pediatr Dermatol. 2011;28(2):210–2.

    Article  PubMed  Google Scholar 

  35. Concha M, Nicklas C, Balcells E, Guzman AM, Poggi H, Leon E, et al. The first case of tinea faciei caused by Trichophyton mentagrophytes var. erinacei isolated in Chile. Int J Dermatol. 2012;51(3):283–5.

    Article  PubMed  Google Scholar 

  36. Charlent AL, Bloch M, Nowak N, Machouart M, Debourgogne A, Cavignaux R, et al. Trichophyton mentagrophytes variété porcellae nouvel agent d’épidémie de teigne chez le cochon d’inde: enquête dans des animaleries. J Mycol Med. 2014;24(2):e76.

    Article  Google Scholar 

  37. Contet-Audonneau N, Leyer C. Émergence d’un dermatophyte transmis par le cochon d’Inde et proche de Trichophyton mentagrophytes var. erinacei: T. mentagrophytes var. porcellae. J Mycol Med. 2010;20(4):321–5.

    Article  Google Scholar 

  38. Nakamura Y, Kano R, Nakamura E, Saito K, Watanabe S, Hasegawa A. Case report. First report on human ringworm caused by Arthroderma benhamiae in Japan transmitted from a rabbit. Mycoses. 2002;45(3–4):129–31.

    Article  CAS  PubMed  Google Scholar 

  39. Sabou M, Denis J, Boulanger N, Forouzanfar F, Glatz I, Lipsker D, et al. Molecular identification of Trichophyton benhamiae in Strasbourg, France: a 9-year retrospective study. Med Mycol. 2018;56(6):723–34.

    Article  PubMed  Google Scholar 

  40. Brasch J, Wodarg S. Morphological and physiological features of Arthroderma benhamiae anamorphs isolated in northern Germany. Mycoses. 2015;58(2):93–8.

    Article  CAS  PubMed  Google Scholar 

  41. Uhrlass S, Wittig F, Koch D, Kruger C, Harder M, Gaajetaan G, et al. Do the new molecular assays-microarray and realtime polymerase chain reaction-for dermatophyte detection keep what they promise? Hautarzt. 2019;70(8):618–26. Article in German.

    CAS  PubMed  Google Scholar 

  42. Ranganathan S, Menon T, Balajee SA. Isolation of Microsporum nanum from a patient with tinea corporis in Madras, India. Mycoses. 1997;40(5–6):229–30.

    Article  CAS  PubMed  Google Scholar 

  43. Ratka P, Slusarczyk E, Sloboda T, Kusmierski W. Case of tinea barbae profunda caused by Microsporum nanum. Przegl Dermatol. 1983;70(5–6):549–52. Article in Polish.

    CAS  PubMed  Google Scholar 

  44. Sinski JT, Flouras K. A survey of dermatophytes isolated from human patients in the United States from 1979 to 1981 with chronological listings of worldwide incidence of five dermatophytes often isolated in the United States. Mycopathologia. 1984;85(1–2):97–120.

    Article  CAS  PubMed  Google Scholar 

  45. Ratka P. Microsporid gonitis caused by Microsporum nanum. Mycopathologia. 1985;92(1):45–7.

    Article  CAS  PubMed  Google Scholar 

  46. Wu SX, Zhu WY, Xia MY, Huang L. Tinea capitis caused by Microsporum nanum. Chin Med J (Engl). 1987;100(9):709–11.

    CAS  Google Scholar 

  47. Ponnighaus JM, Warndorff D, Port G. Microsporum nanum—a report from Malawi (Africa). Mycoses. 1995;38(3–4):149–50.

    Article  CAS  PubMed  Google Scholar 

  48. Martinez E, Ameen M, Tejada D, Arenas R. Microsporum spp. onychomycosis: disease presentation, risk factors and treatment responses in an urban population. Braz J Infect Dis. 2014;18(2):181–6.

    Article  PubMed  Google Scholar 

  49. Bonifaz A, Cordoba-Garcia B, Simancas-Llanos T, Hernandez MA, Martinez-Herrera E, Tirado-Sanchez A. Dermatophytosis caused by Nannizzia nana in two siblings. Rev Iberoam Micol. 2019;36(1):30–3.

    Article  PubMed  Google Scholar 

  50. Rezaei-Matehkolaei A, Makimura K, Graser Y, Seyedmousavi S, Abastabar M, Rafiei A, et al. Dermatophytosis due to Microsporum incurvatum: notification and identification of a neglected pathogenic species. Mycopathologia. 2016;181(1):107–13.

    Article  PubMed  Google Scholar 

  51. Nouripour-Sisakht S, Rezaei-Matehkolaei A, Abastabar M, Najafzadeh MJ, Satoh K, Ahmadi B, et al. Microsporum fulvum, an ignored pathogenic dermatophyte: a new clinical isolation from Iran. Mycopathologia. 2013;176(1–2):157–60.

    Article  PubMed  Google Scholar 

  52. Borelli D. Microsporum racemosum nova species. Acta Med Venez. 1965:148–51.

    Google Scholar 

  53. Albornoz MB. Primer caso de tinea corporis por el Microsporum racemosum (Dante Borelli, 1965). Dermatol Venez. 1972;11(2):310–8.

    Google Scholar 

  54. Daum V, McCloud D. Microsporum racemosum: first isolation in the United States. Mycopathologia. 1976;59(3):183–5.

    Article  CAS  PubMed  Google Scholar 

  55. Rippon JW, Andrews TW. Microsporum racemosum. Second clinical isolation from the United States and the Chicago area. Mycopathologia. 1978;64(3):187–90.

    Article  CAS  PubMed  Google Scholar 

  56. Garcia-Martos P, Gene J, Sole M, Mira J, Ruiz-Henestrosa R, Guarro J. Case of onychomycosis caused by Microsporum racemosum. J Clin Microbiol. 1999;37(1):258–60.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  57. Luque AG, Biasoli MS, Sortino MA, Lupo SH, Bussy RF. Atypical tinea corporis caused by Microsporum gypseum in a subject with acquired immune deficiency syndrome. J Eur Acad Dermatol Venereol. 2001;15(4):374–5.

    CAS  PubMed  Google Scholar 

  58. Sun PL, Ho HT. Concentric rings: an unusual presentation of tinea corporis caused by Microsporum gypseum. Mycoses. 2006;49(2):150–1.

    Article  PubMed  Google Scholar 

  59. Soankasina AH, Rakotozandrindrainy N, Andrianteloasy S, Zafindraibe NJ, Rasamoelina T, Rafalimanana C, et al. Dermatophyte infection caused by Nannizzia gypsea: a rare case report from Madagascar. Med Mycol Case Rep. 2018;20:7–9.

    Article  PubMed  Google Scholar 

  60. Miranda MF, de Brito AC, Zaitz C, de Carvalho TN, Carneiro FR. Microsporum gypseum infection showing a white-paint-dot appearance. Int J Dermatol. 1998;37(12):956–7.

    CAS  PubMed  Google Scholar 

  61. Vollekova A, Tothova I, Kolibasova K, Sevcekova A, Baumgartner J. Atypical infection caused by Microsporum gypseum mimicking circumscribed scleroderma. Bratisl Lek Listy. 1996;97(3):162–4. Article in Slovak.

    CAS  PubMed  Google Scholar 

  62. Romano C, Ghilardi A, Fimiani M. Dystrophic onychomycosis due to Microsporum gypseum. Mycoses. 2006;49(4):335–7.

    Article  CAS  PubMed  Google Scholar 

  63. Romano C, Asta F, Massai L. Tinea incognito due to Microsporum gypseum in three children. Pediatr Dermatol. 2000;17(1):41–4.

    Article  CAS  PubMed  Google Scholar 

  64. Qianggiang Z, Limo Q, Jiajun W, Li L. Report of two cases of tinea infection with scutula-like lesions caused by Microsporum gypseum. Int J Dermatol. 2002;41(6):372–3.

    Article  PubMed  Google Scholar 

  65. Polilli E, Fazii P, Ursini T, Fantini F, Di Masi F, Tontodonati M, et al. Tinea incognito caused by Microsporum gypseum in a patient with advanced HIV infection: a case report. Case Rep Dermatol. 2011;3(1):55–9.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Krunic AL, Cetner A, Tesic V, Janda WM, Worobec S. Atypical favic invasion of the scalp by Microsporum canis: report of a case and review of reported cases caused by Microsporum species. Mycoses. 2007;50(2):156–9.

    Article  PubMed  Google Scholar 

  67. Joly J, Delage G, Auger P, Ricard P. Favus: twenty indigenous cases in the province of Quebec. Arch Dermatol. 1978;114(11):1647–8.

    Article  CAS  PubMed  Google Scholar 

  68. Niczyporuk W, Krajewska-Kulak E, Lukaszuk C. Tinea capitis favosa in Poland. Mycoses. 2004;47(5–6):257–60.

    Article  CAS  PubMed  Google Scholar 

  69. Alanio A, Romand S, Penso-Assathiany D, Foulet F, Botterel F. Microsporum praecox: molecular identification of a new case and review of the literature. Mycopathologia. 2011;171(1):61–5.

    Article  PubMed  Google Scholar 

  70. Sanchez-Castellanos ME, Mayorga-Rodriguez JA, Sandoval-Tress C, Hernandez-Torres M. Tinea incognito due to Trichophyton mentagrophytes. Mycoses. 2007;50(1):85–7.

    Article  PubMed  Google Scholar 

  71. Calcaterra R, Fazio R, Mirisola C, Baggi L. Rosacea-like tinea incognito due to Trichophyton mentagrophytes vr. mentagrophytes. Acta Dermatovenerol Croat. 2013;21(4):263–4.

    PubMed  Google Scholar 

  72. Kumar S, Kamra N, Mahajan BB. Tinea pseudomibricata due to Trichophyton mentagrophytes: a rare case report. J Pak Assoc Dermatol. 2015;25(2):151–3.

    Google Scholar 

  73. Buruiana AM, Mihali CV, Popescu C. Sequence-based identification of a zoophilic strain of Trichophyton interdigitale in a rare case of Tinea blepharo-ciliaris associated with Tinea barbae. Mycopathologia. 2015;180(5–6):403–6.

    Article  PubMed  Google Scholar 

  74. Calles Monar PS, Juarez MA. Eyelid tinea with blepharitis due to Microsporum canis. Arch Soc Esp Oftalmol. 2018;93(10):491–3.

    Article  CAS  PubMed  Google Scholar 

  75. Gugnani HC, Wattal BL, Sandhu RS. Dermatophytes and other keratinophilic fungi recovered from small mammals in India. Mykosen. 1975;18(12):529–38.

    Article  CAS  PubMed  Google Scholar 

  76. Ansari S, Hedayati MT, Nouripour-Sisakht S, Rezaei-Matehkolaei A, Jannesar R, Mohammadi H, et al. A 9-month-old girl from Iran with extensive erythematous plaques due to Trichophyton simii, a zoophilic dermatophyte. Mycopathologia. 2016;181(5–6):451–5.

    Article  PubMed  Google Scholar 

  77. Luchsinger I, Bosshard PP, Kasper RS, Reinhardt D, Lautenschlager S. Tinea genitalis: a new entity of sexually transmitted infection? Case series and review of the literature. Sex Transm Infect. 2015;91(7):493–6.

    Article  PubMed  Google Scholar 

  78. Kupsch C, Czaika VA, Deutsch C, Gräser Y. Trichophyton mentagrophytes—a new genotype of zoophilic dermatophyte causes sexually transmitted infections. J Dtsch Dermatol Ges. 2019;17(5):493–501.

    PubMed  Google Scholar 

  79. Wendrock-Shiga G, Mechtel D, Uhrlass S, Koch D, Kruger C, Nenoff P. Tinea barbae profunda due to Trichophyton mentagrophytes after journey to Thailand: case report and review. Hautarzt. 2017;68(8):639–48. Article in German.

    Article  CAS  PubMed  Google Scholar 

  80. Nenoff P, Verma SB, Vasani R, Burmester A, Hipler UC, Wittig F, et al. The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes—a molecular study. Mycoses. 2019;62(4):336–56.

    Article  CAS  PubMed  Google Scholar 

  81. Suss A, Uhrlass S, Ludes A, Verma SB, Monod M, Kruger C, et al. Extensive tinea corporis due to a terbinafine-resistant Trichophyton mentagrophytes isolate of the Indian genotype in a young infant from Bahrain in Germany. Hautarzt. 2019;70(11):888–96. Article in German.

    Article  PubMed  Google Scholar 

  82. Nenoff P, Verma SB, Uhrlass S, Burmester A, Graser Y. A clarion call for preventing taxonomical errors of dermatophytes using the example of the novel Trichophyton mentagrophytes genotype VIII uniformly isolated in the Indian epidemic of superficial dermatophytosis. Mycoses. 2019;62(1):6–10.

    Article  CAS  PubMed  Google Scholar 

  83. Chowdhary A, Singh A, Singh PK, Khurana A, Meis JF. Perspectives on misidentification of Trichophyton interdigitale/Trichophyton mentagrophytes using internal transcribed spacer region sequencing: urgent need to update the sequence database. Mycoses. 2019;62(1):11–5.

    Article  CAS  PubMed  Google Scholar 

  84. Carlsen BC. A case of tinea pedis due to Trichophyton tonsurans. Intern J Vet Med Res Rep. 2013;2013:204515. https://doi.org/10.5171/2013.204515.

    Article  Google Scholar 

  85. Fernandes S, Amaro C, da Luz MM, Inacio J, Araujo T, Vieira R, et al. Kerion caused by Microsporum audouinii in a child. Med Mycol Case Rep. 2013;2:52–4.

    Article  PubMed  PubMed Central  Google Scholar 

  86. Brasch J, Muller S, Graser Y. Unusual strains of Microsporum audouinii causing tinea in Europe. Mycoses. 2015;58(10):573–7.

    Article  CAS  PubMed  Google Scholar 

  87. Brasch J, Hugel R, Lipowsky F, Graser Y. Tinea corporis caused by an unusual strain of Microsporum audouinii that perforates hair in vitro. Mycoses. 2010;53(4):360–2.

    CAS  PubMed  Google Scholar 

  88. Tan Y, Lin L, Feng P, Lai W. Dermatophytosis caused by Trichophyton rubrum mimicking syphilid: a case report and review of literature. Mycoses. 2014;57(5):312–5.

    Article  PubMed  Google Scholar 

  89. Rouzaud C, Hay R, Chosidow O, Dupin N, Puel A, Lortholary O, et al. Severe dermatophytosis and acquired or innate immunodeficiency: a review. J Fungi (Basel). 2015;2(1):4.

    Article  CAS  Google Scholar 

  90. Wollina U, Hansel G, Uhrlass S, Kruger C, Schonlebe J, Hipler UC, et al. Deep facial mycosis due to Trichophyton verrucosum-molecular genetic identification of the dermatophyte in paraffin-embedded tissue-case report and review of the literature. Mycoses. 2018;61(3):152–8.

    Article  PubMed  Google Scholar 

  91. Su H, Li L, Cheng B, Zhu J, Zhang Q, Xu J, et al. Trichophyton rubrum infection characterized by Majocchi's granuloma and deeper dermatophytosis: case report and review of published literature. Mycopathologia. 2017;182(5–6):549–54.

    Article  PubMed  Google Scholar 

  92. Dai Y, Xia X, Shen H. Multiple abscesses in the lower extremities caused by Trichophyton rubrum. BMC Infect Dis. 2019;19(1):271.

    Article  PubMed  PubMed Central  Google Scholar 

  93. Zhang Y, Mijiti J, Huang C, Song Y, Wan Z, Li R, et al. Deep dermatophytosis caused by Microsporum ferrugineum in a patient with CARD9 mutations. Br J Dermatol. 2019;181(5):1093–5.

    Article  CAS  PubMed  Google Scholar 

  94. Lanternier F, Pathan S, Vincent QB, Liu L, Cypowyj S, Prando C, et al. Deep dermatophytosis and inherited CARD9 deficiency. N Engl J Med. 2013;369(18):1704–14.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  95. Alves de Medeiros AK, Lodewick E, Bogaert DJ, Haerynck F, Van Daele S, Lambrecht B, et al. Chronic and invasive fungal infections in a family with CARD9 deficiency. J Clin Immunol. 2016;36(3):204–9.

    Article  PubMed  Google Scholar 

  96. Simpson JK, Frobel P, Seneviratne SL, Brown M, Lowe DM, Grimbacher B, et al. Invasive dermatophyte infection with Trichophyton interdigitale is associated with prurigo-induced pseudoperforation and a signal transducer and activator of transcription 3 mutation. Br J Dermatol. 2018;179(3):750–4.

    Article  CAS  PubMed  Google Scholar 

  97. Abusleme L, Diaz PI, Freeman AF, Greenwell-Wild T, Brenchley L, Desai JV, et al. Human defects in STAT3 promote oral mucosal fungal and bacterial dysbiosis. JCI Insight. 2018;3(17):e122061.

    Article  PubMed Central  Google Scholar 

  98. Huovinen S, Tunnela E, Huovinen P, Kuijpers AF, Suhonen R. Human onychomycosis caused by Trichophyton equinum transmitted from a racehorse. Br J Dermatol. 1998;138(6):1082–4.

    Article  CAS  PubMed  Google Scholar 

  99. Mapelli ET, Colombo L, Crespi E, Menni S. Toenail onychomycosis due to Trichophyton violaceum complex. (An unusual, emerging localization of this anthropophilic dermatophyle). Mycoses. 2012;55(2):193–4.

    CAS  PubMed  Google Scholar 

  100. Khanna D, Goel A, Kedar A, Manchanda V, Agarwal S. Trichophyton tonsurans induced recurrent onychomadesis in a very young infant. Pediatr Dermatol. 2013;30(3):390–1.

    Article  PubMed  Google Scholar 

  101. Macura AB, Krzysciak P, Skora M, Gniadek A. Case report: onychomycosis due to Trichophyton schoenleinii. Mycoses. 2012;55(2):e18–9.

    PubMed  Google Scholar 

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Correspondence to Marie-Pierre Hayette .

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Hayette, MP., Sacheli, R. (2021). Unusual Dermatophytosis Presentations and New Emerging Dermatophytes Species. In: Bouchara, JP., Nenoff, P., Gupta, A.K., Chaturvedi, V. (eds) Dermatophytes and Dermatophytoses. Springer, Cham. https://doi.org/10.1007/978-3-030-67421-2_5

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