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Periocular Fillers–Related Complications: Imaging Features

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Atlas of Orbital Imaging

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1 Signs and Symptoms

Each complication has its own distinctive features; these commonly include local swelling and inflammation. In cases of vascular compromise, pain, paresthesia, erythema, blisters, skin necrosis, and vision loss can occur.

2 Differential Diagnosis

Filler-related complications may mimic:

  1. 1.

    True pathology (primary/recurrent tumor). Both may demonstrate enhancement/increased uptake on FDG PET-CT/MRI. Restricted diffusion on DWI and atypical location for filler injection should prompt a potential for malignancy and warrant biopsy

  2. 2.

    Dermatological entities, including sarcoidosis, cutaneous lymphoma, and dermatomyositis

3 Diagnosis

  • MRI is the preferred modality for diagnosis, anatomic delineation, and differential diagnosis of filler-related complications especially in unclear cases and in long-term filler-related complications.

  • CT is superior for identification of calcifications, which are pathognomonic of certain filler (CaHA) and certain filler-related complications.

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References

  1. Funt D, Pavicic T. Dermal fillers in aesthetics: an overview of adverse events and treatment approaches. Clin Cosmet Investig Dermatol. 2013;6:295–316.

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Author information

Authors and Affiliations

  1. Department of Plastic and Reconstructive Surgery, Assaf Harofeh Medical Center, Zerifin, Israel

    S. Cohen

  2. Department of Radiology, Sourasky Medical Center, Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel

    D. Niry

  3. The Goldschleger Eye Institution, Sheba Medical Center, Ramat Gan, Israel

    A. Priel

Authors
  1. S. Cohen
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  2. D. Niry
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  3. A. Priel
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Editor information

Editors and Affiliations

  1. Orbital Ophthalmic Plastic & Lacrimal Surgery Institute, Sheba Medical Center, Tel Hashomer, Tel Aviv, Israel

    Guy Ben Simon

  2. Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer, Israel

    Gahl Greenberg

  3. Orbital Ophthalmic Plastic & Lacrimal Surgery Institute, Sheba Medical Center, Tel Hashomer, Israel

    Daphna Prat

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Cohen, S., Niry, D., Priel, A. (2021). Periocular Fillers–Related Complications: Imaging Features. In: Ben Simon, G., Greenberg, G., Prat, D. (eds) Atlas of Orbital Imaging . Springer, Cham. https://doi.org/10.1007/978-3-030-41927-1_120-1

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  • DOI: https://doi.org/10.1007/978-3-030-41927-1_120-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-41927-1

  • Online ISBN: 978-3-030-41927-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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