Skip to main content

Abstract

In this chapter, techniques and innovations of peroral pancreatoscopy are reviewed focusing on the traditional “mother-baby” method using video pancreatoscopes and recent single-operator cholangiopancreatoscopy. A new video pancreatoscope has been recently developed with refinement of the optical performance and improvement of the durability. It enables the more detailed narrow-band imaging (NBI) examination which further enhances diagnostic capability. Single-operator pancreatoscopy using the SpyGlass system has simplified direct visualization of the pancreatic duct and has been applied in endotherapy for pancreatic duct stones. Further refinement in endoscopic caliber, tip deflection, and irrigation system, as well as the optical resolution, is required for more routine application in pancreatic diseases.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  1. Takagi K, Takegoshi T (1974) Endoscopic diagnosis of pancreatic cancer [in Japanese]. Stom Intes 9:1533–1541

    Google Scholar 

  2. Ohashi K, Murakami Y, Maruyama M (1982) Four cases of a mucous secreting pancreatic cancer [in Japanese]. Prog Dig Endosc 20:348–351

    Google Scholar 

  3. Kodama T, Sato H, Horii Y et al (1999) Pancreatoscopy for the next generation: development of the peroral electronic pancreatoscope system. Gastrointest Endosc 49:366–371

    Article  CAS  Google Scholar 

  4. Chen YK, Pleskow DKL (2006) Results from the first human use clinical series utilizing a new peroral cholangiopancreatoscopy system (SpyGlass Direct Visualization System). Gastrointest Endosc 63:AB88

    Google Scholar 

  5. Kodama T, Koshitani T, Sato H et al (2002) Electronic pancreatoscopy for the diagnosis of pancreatic diseases. Am J Gastroenterol 97:617–622

    Article  Google Scholar 

  6. Navaneethan U, Hasan MK, Kommaraju K et al (2016) Digital, single-operator cholangiopancreatoscopy in the diagnosis and management of pancreatobiliary disorders: a multicenter clinical experience (with video). Gastrointest Endosc 84:649–655

    Article  Google Scholar 

  7. Prachayakul V, Aswakul P, Kachintorn U (2011) Overtube-assisted direct peroral pancreatoscopy using an ultraslim gastroscope in a patient suspected of having an intraductal papillary mucinous neoplasm. Endoscopy 43:E279–E280

    Article  Google Scholar 

  8. Cheon YK, Moon JH, Choi HJ et al (2011) Direct peroral pancreatoscopy with an ultraslim endoscope for the evaluation of intraductal papillary mucinous neoplasms. Endoscopy 43:E390–E391

    Article  Google Scholar 

  9. Koshitani T, Kodama T (2005) The role of endoscopy for the diagnosis of intraductal papillary mucinous tumor of the pancreas. Tech Gastrointest Endosc 7:200–210

    Article  Google Scholar 

  10. Ringold DA, Shah RJ (2009) Peroral pancreatoscopy in the diagnosis and management of intraductal papillary mucinous neoplasia and indeterminate pancreatic duct pathology. Gastrointest Endosc Clin N Am 19:601–613

    Article  Google Scholar 

  11. Mukai H, Yasuda K, Nakajima M (1998) Differential diagnosis of mucin-producing tumors of the pancreas by intraductal ultrasonography and peroral pancreatoscopy. Endoscopy 30:A99–A102

    Article  Google Scholar 

  12. Yamaguchi T, Hara T, Tsuyuguchi T et al (2000) Peroral pancreatoscopy in the diagnosis of mucin-producing tumors of the pancreas. Gastrointest Endosc 52:67–73

    Article  CAS  Google Scholar 

  13. Hara T, Yamaguchi T, Ishihara T et al (2002) Diagnosis and patient management of intraductal papillary-mucinous tumor of the pancreas by using peroral pancreatoscopy and intraductal ultrasonography. Gastroenterology 122:34–43

    Article  Google Scholar 

  14. Yamao K, Ohashi K, Nakamura T et al (2003) Efficacy of peroral pancreatoscopy in the diagnosis of pancreatic diseases. Gastrointest Endosc 57:205–209

    Article  Google Scholar 

  15. Itoi T, Neuhaus H, Chen YK (2009) Diagnostic value of image-enhanced video cholangiopancreatoscopy. Gastrointest Endosc Clin N Am 19:557–566

    Article  Google Scholar 

  16. Miura T, Igarashi Y, Okano N et al (2010) Endoscopic diagnosis of intraductal papillary-mucinous neoplasm of the pancreas by means of peroral pancreatoscopy using a small-diameter videoscope and narrow-band imaging. Dig Endosc 22:119–123

    Article  Google Scholar 

  17. Arnelo U, Siiki A, Swahn F et al (2014) Single-operator pancreatoscopy is helpful in the evaluation of suspected intraductal papillary mucinous neoplasms (IPMN). Pancreatology 14:510–514

    Article  Google Scholar 

  18. Navez J, Hubert C, Gigot JF et al (2015) Impact of intraoperative pancreatoscopy with intraductal biopsies on surgical management of intraductal papillary mucinous neoplasm of the pancreas. J Am Coll Surg 221:982–987

    Article  Google Scholar 

  19. Pucci MJ, Johnson CM, Punja VP et al (2014) Intraoperative pancreatoscopy: a valuable tool for pancreatic surgeons? J Gastrointest Surg 18:1100–1107

    Article  Google Scholar 

  20. Afify AM, al-Khafaji BM, Kim B et al (2003) Endoscopic ultrasound-guided fine needle aspiration of the pancreas: diagnostic utility and accuracy. Acta Cytol 47:341–348

    Article  Google Scholar 

  21. Eloubeidi MA, Jhala D, Chhieng DC et al (2003) Yield of endoscopic ultrasound-guided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma. Cancer 99:285–292

    Article  Google Scholar 

  22. Uehara H, Nakaizumi A, Tatsuta M et al (1997) Diagnosis of carcinoma in situ of the pancreas by peroral pancreatoscopy and pancreatoscopic cytology. Cancer 79:454–461

    Article  CAS  Google Scholar 

  23. Yamaguchi T, Shirai Y, Ishihara T et al (2005) Pancreatic juice cytology in the diagnosis of intraductal papillary mucinous neoplasm of the pancreas. Cancer 104:2830–2836

    Article  Google Scholar 

  24. Nagayoshi Y, Aso T, Ohtsuka T et al (2014) Peroral pancreatoscopy using the SpyGlass system for the assessment of intraductal papillary mucinous neoplasm of the pancreas. J Hepatobiliary Pancreat Sci 21:410–417

    Article  Google Scholar 

  25. Sherman S, Lehman G, Hawes R et al (1991) Pancreatic ductal stones: frequency of successful endoscopic removal and improvement in symptoms. Gastrointest Endosc 37:511–517

    Article  CAS  Google Scholar 

  26. Nguyen NQ, Binmoeller KF, Shah JN (2009) Cholangioscopy and pancreatoscopy (with videos). Gastrointest Endosc 70:1200–1210

    Article  Google Scholar 

  27. Shah RJ (2015) Innovations in intraductal endoscopy. Gastrointest Endosc Clin N Am 25:779–792

    Article  Google Scholar 

  28. Attwell AR, Patel S, Kahaleh M et al (2015) ERCP with per-oral pancreatoscopy-guided laser lithotripsy for calcific chronic pancreatitis: a multicenter U.S. experience. Gastrointest Endosc 82:311–318

    Article  Google Scholar 

  29. Tringali A, Lemmers A, Meves V et al (2015) Intraductal biliopancreatic imaging: European Society of Gastrointestinal Endoscopy (ESGE) technology review. Endoscopy 47:739–753

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Section Editor information

Electronic Supplementary Material (S)

Fig6_Video (MP4 51345 kb)

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Koshitani, T., Kodama, T. (2020). Pancreatoscopy: Techniques and Innovations. In: Testoni, P.A., Inoue, H., Wallace, M.B. (eds) Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-29964-4_74-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-29964-4_74-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29964-4

  • Online ISBN: 978-3-030-29964-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics