Skip to main content
  • 1256 Accesses

Abstract

Disparities in outcomes for pulmonary diseases are the most evident of all chronic diseases. Because of disproportional poverty and urban living, African Americans have an increased exposure to indoor and outdoor pollution, occupational and environmental hazards, and tobacco smoke, which contribute to disparities in prevalence and outcomes of COPD. African American patients had a higher rate of asthma-COPD overlap with asthma as a predominant cause for resistant treatment and hospital re-admission. African Americans also have a higher rate of chronic bronchitis and a lower rate of emphysema when compared to European Americans. African Americans with COPD are significantly younger, smoke less, report concurrent asthma more frequently, and have less radiographic emphysema on volumetric computed tomography. There is more obstructive sleep apnea, interrupted sleep, and daytime sleepiness in African Americans. Finally, sarcoidosis and its increased severity in African Americans is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 34.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 44.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Schraufnagel DE, Blasi F, Kraft M, et al. An official American Thoracic Society/European Respiratory Society policy statement: disparities in respiratory health. Am J Respir Crit Care Med. 2013;188(7):865–71.

    Article  PubMed  Google Scholar 

  2. Staton GW, Ochoa CD. Chronic obstructive pulmonary disease. In: McKean SC, Ross JJ, Dressler DD, Scheurer DB, editors. Principles and practice of hospital medicine. 2nd ed. New York: McGraw-Hill. http://0-accessmedicine.mhmedical.com.crusher.neomed.edu/content.aspx?bookid=1872&sectionid=146988856. Accessed 12 June 2019.

  3. Pleasants RA, Riley IL, Mannino DM. Defining and targeting health disparities in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2016;11:2475–96.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Chatila WM, Wynkoop WA, Vance G, Criner GJ. Smoking patterns in African Americans and whites with advanced COPD. Chest. 2004;125(1):15–21.

    Article  PubMed  Google Scholar 

  5. Foreman MG, Zhang L, Murphy J, et al. Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPD Gene Study. Am J Respir Crit Care Med. 2011;184:414–20.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Hardin M, Silverman EK, Barr RG, et al. The clinical features of the overlap between COPD and asthma. Respir Res. 2011;12:127. https://doi.org/10.1186/1465-9921-12-127.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Mina N, Soubani AO, Cote ML, et al. The relationship between COPD and lung cancer in African American patients. Clin Lung Cancer. 2012;13(2):149–56.

    Article  PubMed  Google Scholar 

  8. Dransfield MT, Davis JJ, Gerald LB, Bailey WC. Racial and gender differences in susceptibility to tobacco smoke among patients with chronic obstructive pulmonary disease. Respir Med. 2006;100(6):1110–6.

    Article  PubMed  Google Scholar 

  9. Kirkpatrick dP, Dransfield MT. Racial and sex differences in chronic obstructive pulmonary disease susceptibility, diagnosis, and treatment. Curr Opin Pulm Med. 2009;15(2):100–4.

    Article  PubMed  Google Scholar 

  10. Kamil F, Pinzon I, Foreman MG. Sex and race factors in early-onset COPD. Curr Opin Pulm Med. 2013;19(2):140–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Han MK, Curran-Everett D, Dransfield MT, et al. Racial differences in quality of life in patients with COPD. Chest. 2011;140(5):1169–76.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lee H, Shin SH, Gu S, et al. Racial differences in comorbidity profile among patients with chronic obstructive pulmonary disease. BMC Med. 2018;16:178.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Goto T, Faridi MK, Gibo K, et al. Sex and racial/ethnic differences in the reason for 30-day readmission after COPD hospitalization. Respir Med. 2017;131:6–10.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Asthma and African Americans. U.S. Department of Health and Human Services Office of Minority Health. 2018. https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=4&lvlid=15. Accessed 12 June 2019.

  15. Brown RW, Cappelletti CS. Reaching beyond disparity: safely improving asthma control in the at-risk African American population. J Natl Med Assoc. 2013;105(2):138–49.

    Article  PubMed  Google Scholar 

  16. Krishnan JA, Diette GB, Skinner EA, et al. Race and sex differences in consistency of care with national asthma guidelines in managed care organizations. Arch Intern Med. 2001;161(13):1660–8.

    Article  CAS  PubMed  Google Scholar 

  17. Holt EW, Theall KP, Rabito FA. Individual, housing, and neighborhood correlates of asthma among young urban children. J Urban Health. 2013;90(1):116–29.

    Article  PubMed  Google Scholar 

  18. Bruzzese JM, Kingston S, Falletta KA, et al. Individual and neighborhood factors associated with undiagnosed asthma in a large cohort of urban adolescents. J Urban Health. 2019;96(2):252–61.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Loman DG, Kwong CG, Henry LD, et al. Asthma control and obesity in urban African American children. J Asthma. 2017;54(6):578–83.

    Article  PubMed  Google Scholar 

  20. Brehm JM, Schuemann B, Fuhlbrigge AL, et al. Serum vitamin D and severe asthma exacerbations in the childhood asthma management program study. J Allergy Clin Immunol. 2010;126(1):52–56.e5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Harris SS. Vitamin D and African Americans. J Nutr. 2006;136(4):1126–9.

    Article  CAS  PubMed  Google Scholar 

  22. Hall SC, Agrawal DK. Vitamin D and bronchial asthma: an overview of the last five years. Clin Ther. 2017;39(5):917–29.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Oh S, Du R, Zeiger AM, et al. Breastfeeding associated with higher lung function in African American youths with asthma. J Asthma. 2017;54(8):856–65.

    Article  PubMed  Google Scholar 

  24. Gerke AK, Judson MA, Cozier YC, et al. Disease burden and variability in sarcoidosis. Ann Am Thorac Soc. 2017;14(Suppl 6):S421–8.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Cozier YC, Berman JS, Palmer JR, Boggs DA, Serlin DM, Rosenberg L. Sarcoidosis in black women in the United States: data from the Black Women’s Health Study. Chest. 2011;139:144–50.

    Article  PubMed  Google Scholar 

  26. Gideon NM, Mannino DM. Sarcoidosis mortality in the United States 1979–1991: an analysis of multiple-cause mortality data. Am J Med. 1996;100:423–7.

    Article  CAS  PubMed  Google Scholar 

  27. Newman LS, Rose CS, Bresnitz EA, ACCESS Research Group, et al. A case control etiologic study of sarcoidosis: environmental and occupational risk factors. Am J Respir Crit Care Med. 2004;170:1324–30.

    Article  PubMed  Google Scholar 

  28. Levin AM, Adrianto I, Datta I, et al. Association of HLA-DRB1 with sarcoidosis susceptibility and progression in African Americans. Am J Respir Cell Biol. 2015;53(2):206–16.

    Article  CAS  Google Scholar 

  29. Mirsaeidi M, Machado RF, Schraufnagel D, et al. Racial difference in sarcoidosis mortality in the United States. Chest. 2015;147(2):438–49.

    Article  PubMed  Google Scholar 

  30. Mehta D, Lubitz SA, Frankel Z, et al. Cardiac involvement in patients with sarcoidosis: diagnostic and prognostic value of outpatient testing. Chest. 2008;133(6):1426–35.

    Article  PubMed  Google Scholar 

  31. Judson MA, Boan AD, Lackland DT. The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States. Sarcoidosis Vasc Diffuse Lung Dis. 2012;29:119–27.

    CAS  PubMed  Google Scholar 

  32. Rabin DL, Richardson MS, Stein SR, Yeager H. Sarcoidosis severity and socioeconomic status. Eur Respir J. 2001;18:499–506.

    Article  CAS  PubMed  Google Scholar 

  33. Beegle SH, Barba K, Gobunsuy R, Judson MA. Current and emerging pharmacological treatments for sarcoidosis: a review. Drug Des Devel Ther. 2013;7:325–38.

    CAS  PubMed  PubMed Central  Google Scholar 

  34. Chen X, Wang R, Zee P, et al. Racial/ethnic differences in sleep disturbances: the Multi-Ethnic Study of Atherosclerosis (MESA). Sleep. 2015;38(6):877–88.

    PubMed  PubMed Central  Google Scholar 

  35. Dudley KA, Patel SR. Disparities and genetic risk factors in obstructive sleep apnea. Sleep Med. 2016;18:96–102.

    Article  PubMed  Google Scholar 

  36. Ruiter ME, DeCoster J, Jacobs L, Lichstein KL. Sleep disorders in African Americans and Caucasian Americans: a meta-analysis. Behav Sleep Med. 2010;8(4):246–59.

    Article  PubMed  Google Scholar 

  37. Scharf SM, Seiden L, DeMore J, Carter-Pokras O. Racial differences in clinical presentation of patients with sleep-disordered breathing. Sleep Breath. 2004;8:173–83.

    Article  PubMed  Google Scholar 

  38. Joosten SA, Khoo JK, Edwareds BA, et al. Improvement in obstructive sleep apnea with weight loss in dependent on body position during sleep. Sleep. 2017;40(5):zsx047. https://doi.org/10.1093/sleep/zsx047.

    Article  Google Scholar 

  39. Hayes AL, Spilsbury JC, Patel SR. The Epworth score in African American populations. J Clin Sleep Med. 2009;5:344–8.

    PubMed  PubMed Central  Google Scholar 

  40. Jhamb M, Unruh M. Bidirectional relationship of hypertension with obstructive sleep apnea. Curr Opin Pulm Med. 2014;20(6):558–64.

    Article  PubMed  Google Scholar 

  41. Epstein LJ, Kristo D, Strollo PJ Jr, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263–76.

    PubMed  Google Scholar 

  42. Schwartz SW, Sebastiao Y, Rosas J, et al. Racial disparity in adherence to positive airway pressure among US veterans. Sleep Breath. 2016;20(3):947–55.

    Article  PubMed  Google Scholar 

  43. Bakker JP, Weaver TE, Parthasarathy S, Aloia MS. Adherence to CPAP: what should we be aiming for, and how can we get there? Chest. 2019;155(6):1272–87.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Hall, G.L. (2020). Important Differences in Pulmonary Diseases. In: Patient-Centered Clinical Care for African Americans. Springer, Cham. https://doi.org/10.1007/978-3-030-26418-5_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-26418-5_9

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-26417-8

  • Online ISBN: 978-3-030-26418-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics