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Impact of Antibiotic Misuse on Genetics Alterations of Bacteria

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CMBEBIH 2019 (CMBEBIH 2019)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 73))

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Abstract

Antibiotic resistance is a live issue when it comes to public health and emerging infectious diseases. Opinion of many experts in this field is that misuse or overuse of antibiotics have contributed to fast development of antibiotic resistance. This paper is focused on genetics alterations of bacteria caused by misuse of antibiotics. The acquisition of resistance can occur by horizontal or vertical transmission, so we described the mechanisms of resistance, as well as evolution of resistance genes. We explained mutagenesis induced by antibiotics, as well as recombination and lateral transfer mechanisms. At the end we got to multiple drug resistant bacteria, as a most urgent threat to a public health. Many strains of bacteria become resistant, or in many cases multi-resistant to many therapeutic drugs because of their ability to adapt to the environment and to develop different mechanisms of resistance to most old and new antimicrobial agents. Some strains have become resistant to practically all of the commonly available agents.

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Conflict of Interest

Authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000, Sarajevo, Bosnia and Herzegovina

    Emina Aruković, Dina Fetahović & Belma Pehlivanović

Authors
  1. Emina Aruković
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  2. Dina Fetahović
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  3. Belma Pehlivanović
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Corresponding author

Correspondence to Emina Aruković .

Editor information

Editors and Affiliations

  1. International Burch University, Sarajevo, Bosnia and Herzegovina

    Almir Badnjevic

  2. Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina

    Ranko Škrbić

  3. International Burch University, Sarajevo, Bosnia and Herzegovina

    Lejla Gurbeta Pokvić

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Aruković, E., Fetahović, D., Pehlivanović, B. (2020). Impact of Antibiotic Misuse on Genetics Alterations of Bacteria. In: Badnjevic, A., Škrbić, R., Gurbeta Pokvić, L. (eds) CMBEBIH 2019. CMBEBIH 2019. IFMBE Proceedings, vol 73. Springer, Cham. https://doi.org/10.1007/978-3-030-17971-7_93

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  • DOI: https://doi.org/10.1007/978-3-030-17971-7_93

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17970-0

  • Online ISBN: 978-3-030-17971-7

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