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Natural Products Isolation pp 301–340Cite as

Hyphenated Techniques and Their Applications in Natural Products Analysis

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 864))

Abstract

A technique where a separation technique is coupled with an online spectroscopic detection technology is known as hyphenated technique, e.g., GC–MS, LC–PDA, LC–MS, LC–FTIR, LC–NMR, LC–NMR–MS, and CE–MS. Recent advances in hyphenated analytical techniques have remarkably widened their applications to the analysis of complex biomaterials, especially natural products. This chapter focuses on the applications of hyphenated techniques to pre-isolation and isolation of natural products, dereplication, online partial identification of compounds, chemotaxonomic studies, chemical finger-printing, quality control of herbal products, and metabolomic studies, and presents specific examples. However, a particular emphasis has been given on the hyphenated techniques that involve an LC as the separation tool.

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  1. Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, Wolverhampton, WV11LY, UK

    Satyajit D. Sarker

  2. Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, UK

    Lutfun Nahar

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  1. Satyajit D. Sarker
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Correspondence to Satyajit D. Sarker .

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  1. School of Applied Sciences, Department of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom

    Satyajit D. Sarker

  2. , Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, LE1 9BH, United Kingdom

    Lutfun Nahar

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Sarker, S.D., Nahar, L. (2012). Hyphenated Techniques and Their Applications in Natural Products Analysis. In: Sarker, S., Nahar, L. (eds) Natural Products Isolation. Methods in Molecular Biology, vol 864. Humana Press. https://doi.org/10.1007/978-1-61779-624-1_12

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