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Introduction to Genomics

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Molecular Profiling

Part of the book series: Methods in Molecular Biology ((MIMB,volume 823))

Abstract

The Science of Genomes: Only within the past few decades have scientists progressed from the analysis of a single or a small number of genes at once to the investigation of thousands of genes, going from the study of the units of inheritance to the investigation of the whole genome of an organism. The science of the genomes, or “genomics,” initially dedicated to the determination of DNA sequences (the nucleotide order on a given fragment of DNA), has promptly expanded toward a more functional level – studying the expression profiles and the roles of both genes and proteins. The aim of the chapter is to review some basic assumptions and definitions that are the fabric of genomics, and to elucidate key concepts and approaches on which genomics rely.

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Acknowledgment

The authors would like to thank Dr. Anna Pistocchi for critical reading of the manuscript.

Author information

Authors and Affiliations

  1. Division of Functional and Reproductive Biology, Department of Biology, University of Milan, Milan (MI), Italy

    Luca Del Giacco

  2. Department of Biology, University of Milan, Milan (MI), Italy

    Cristina Cattaneo

Authors
  1. Luca Del Giacco
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  2. Cristina Cattaneo
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Corresponding author

Correspondence to Luca Del Giacco .

Editor information

Editors and Affiliations

  1. Center for Applied Proteomics and, George Mason University, University Blvd. 10900, Manassas, 20110, Virginia, USA

    Virginia Espina

  2. Center for Applied Proteomics &, George Mason University, University Blvd. 10900, Manassas, 20110, Virginia, USA

    Lance A. Liotta

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Del Giacco, L., Cattaneo, C. (2012). Introduction to Genomics. In: Espina, V., Liotta, L. (eds) Molecular Profiling. Methods in Molecular Biology, vol 823. Humana Press. https://doi.org/10.1007/978-1-60327-216-2_6

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  • DOI: https://doi.org/10.1007/978-1-60327-216-2_6

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-215-5

  • Online ISBN: 978-1-60327-216-2

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