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Electrospray Mass Spectrometry for Fumonisin Detection and Method Validation

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Mycotoxins and Food Safety

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 504))

Abstract

Fumonisins are a structurally related group of mycotoxins, characterized by a 19-20 carbon aminopolyhydroxy-alkyl chain which is diesterified with propane-1,2,3tricarboxylic acid (tricarballylic acid). These mycotoxins are commonly found in corn and corn-based food products and have been linked to a variety of animal toxicities. The widespread prevalence of fumonisins and the toxicity associated with ingestion has resulted in a number of analytical methods for determining the amount of fumonisins present in foods. Among the most common of these methods are liquid chromatographic (LC) separation with fluorescence detection, enzyme-linked immunosorbent assay (ELISA) and LC /mass spectrometry. LC and ELISA give quantitative results while LC/MS provide quantitative analysis as well as confirmation of identity of the fumonisins.

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Authors and Affiliations

  1. Center for Food Safety and Applied Nutrition U.S. Food and Drug Administration, Washington, DC, 20204

    Steven M. Musser, Robert M. Eppley & Mary W. Trucksess

Authors
  1. Steven M. Musser
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  2. Robert M. Eppley
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  3. Mary W. Trucksess
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Editor information

Editors and Affiliations

  1. Medallion Laboratories Division, General Mills, Inc., Minneapolis, Minnesota, USA

    Jonathan W. DeVries

  2. Center for Food Safety and Applied Nutrition Division of Natural Products, Food and Drug Administration, Washington, D.C., USA

    Mary W. Trucksess

  3. National Center for Food Safety & Technology, Food and Drug Administration, Summit-Argo, Illinois, USA

    Lauren S. Jackson

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© 2002 Springer Science+Business Media New York

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Musser, S.M., Eppley, R.M., Trucksess, M.W. (2002). Electrospray Mass Spectrometry for Fumonisin Detection and Method Validation. In: DeVries, J.W., Trucksess, M.W., Jackson, L.S. (eds) Mycotoxins and Food Safety. Advances in Experimental Medicine and Biology, vol 504. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0629-4_10

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  • DOI: https://doi.org/10.1007/978-1-4615-0629-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5166-5

  • Online ISBN: 978-1-4615-0629-4

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