Abstract
Liquid sampling is critical for several chemical analysis of biological sample because sampling process may affect reliability of obtained results related to the composition of the analyzed medium. This process requires instruments that should be extremely small in size, biocompatible, and minimally invasive. With recent technological advances, the sampling and analysis stages can be merged by, for example, integrating ultraminiaturized sensing techniques into implantable probe architectures. One objective of this approach is to provide continuous analysis, to reduce the required sample volume and to provide real-time characterization of the sampled biological environment. We observed several multimodal probes that handle both, sampling, sensing, and analysis with embedded data processing system. In this section, we review various techniques for implementing molecular detection methods in miniaturized medical instruments for chemical analysis.
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The authors acknowledge the financial support from the Canada Excellence Research Chair in Photonic Innovations. The authors also acknowledge financial support from the Natural Sciences and Engineering Research Council of Canada (NSERC).
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Miled, A., Landari, H., Boukadoum, M., Messaddeq, Y. (2021). Sensing and Sampling Probes for Bio-applications. In: Sawan, M. (eds) Handbook of Biochips. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6623-9_68-1
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DOI: https://doi.org/10.1007/978-1-4614-6623-9_68-1
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