Abstract
Erythropoietin is a growth factor for erythroid and myeloid progenitor cells and a differentiation hormone necessary for the blast transformation of CFU-E to proerythroblasts.
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References
. Erslev, A.J. 1981. Erythroid adaptation to altitude. Blood Cells 7: 495 – 508.
. Reissmann, K.R. 1950. Studies on the mechanism of erythropoietic stimulation in parabiotic rats during hypoxia. Blood 5: 372.
. Erslev, A.J. 1953. Humoral regulation of red cell production. Blood 8: 349.
. Jacobson, L.O., E. Goldwasser, W. Freed, L. Plzak. 1957. Role of the kidney in erythropoiesis. Nature 179: 633.
. Caro, J., A.J. Erslev. 1984. Biologic and immunologic erythropoietin in extracts from hypoxic whole rat kidneys and in their glomerular and tubular fractions. J. Lab. Clin. Med. 103: 922.
. Koury, S.T., M. Boudurant, M.J. Koury. 1988. Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization. Blood 71: 524.
. Lacombe, C., J-L DaSilva, P. Bruneval, et al. 1988. Pertibular cells are the site of erythropoietin synthesis in the murine hypoxic kidney. J. Clin. Invest. 81: 620.
. Goldberg, M.A., S.P. Dunning, H.F. Bunn. 1988. Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein. Science 242: 1424.
. Jacobs, K., L. Shoemaker, R. Rusersdorf, et al. 1985. Isolation and characterization of genomic and cDNA clones of human erythropoietin. Nature 313: 806.
. Fried, W. 1972. The liver as a source of extrarenal erythropoietin production. Blood 40: 671.
. Zanjani, E.D., J. Poster, H. Burlington, et al. 1977. Liver as the primary site of erythropoietin formation in the fetus. J. Lab. Clin. Med. 89: 640.
. Spivak, J.L. 1986. The mechanism of action of erythropoietin. Int. J. Cell Cloning 4: 139.
. Erslev, A.J., J. Wilson, J. Caro. 1987. Erythropoietin titers in anemic, non-uremic patients. J. Lab. Clin. Med. 109: 429.
. Erslev, A.J., J. Caro. 1983. Pathophysiology and classification of polycythemia. Scand. J. Haemat. 31: 287.
. Erslev, A.J., J. Caro. 1984. Pure erythrocytosis classified according to erythropoietin titers. Am. J. Med. 76: 57.
. Winearls, CG., M.J. Pippard, M.R. Downing, et al. 1986. Effect of human erythropoietin derived from recombinant DNA on the anemia of patients maintained by chronic haemodialysis. Lancet II: 1175.
. Eschbach, J.W., J.C. Egrie, M.R. Downing, et al. 1987. Correction of the anemia of end stage renal disease with recombinant human erythropoietin. N. Engl. J. Med. 316: 71.
. Rhondeau, S.M., R.D. Christensen, M.P. Ross, et al. 1988. Responsiveness to recombinant human erythropoietin of marrow erythroid progenitors from infants with the anemia of prematurity. J. Ped. 112: 935.
. Means, R.T., N.J. Olsen, S.B. Krantz, et al. 1987. Treatment of the anemia of rheumatoid arthritis with recombinant human erythropoietin. Blood 70(Supp) 139A.
. Al-Katti, A., T. Papayannopoulou, G. Knitter, et al. Cooperative enhancement of F-cell formation in baboons treated with erythropoietin and hydroxyurea. Blood 72: 817.
. Erslev, A.J. 1987. Erythropoietin coming of age. N. Engl. J. Med. 316: 101.
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© 1989 Plenum Press, New York
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Erslev, A.J., Caro, J. (1989). Erythropoietin: From Mountain Top to Bedside. In: Ascensao, J.L., Zanjani, E.D., Tavassoli, M., Levine, A.S., MacKintosh, F.R. (eds) Molecular Biology of Erythropoiesis. Advances in Experimental Medicine and Biology, vol 271. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0623-8_1
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DOI: https://doi.org/10.1007/978-1-4613-0623-8_1
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