Abstract
Pesticides play an important role in clinical and forensic toxicology, associated mainly with high acute exposures, as causes of suicidal, homicidal, and accidental poisonings due to misuse by operators. Pesticide analysis in postmortem samples is difficult; it must be used a sensitive method, due to the high toxicity of those compounds; versatile, due to the high variety of samples and robust, to be easily incorporated in the routine flow.
The present work describes a simple and successful method that allows the screening and qualitative confirmation of more than 43 pesticide active substances in postmortem samples, using a solid-phase extraction method and GC/MS analysis. This method is routinely applied to different postmortem matrices. Sample preparation, analytical parameters, controls, and acceptance criteria are fully presented.
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Fonseca, S. et al. (2022). Identification of Pesticides in Postmortem Samples: Applicability in Forensic Toxicology. In: Gallardo, E., Barroso, M. (eds) Pesticide Toxicology. Methods in Pharmacology and Toxicology. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1928-5_8
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DOI: https://doi.org/10.1007/978-1-0716-1928-5_8
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