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Stem Cell Nanotechnology pp 181–192Cite as

Nanoscaled Materials for Drug Delivery into Cells/Stem Cells

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 2125))

Abstract

The successful and efficient transport and delivery of drugs and biomolecules to cells/stem cells have revealed the main challenge in clinical therapy development. Special materials and systems are used in smart drug delivery to improve the effectiveness by controlling drug release and decreasing the side effects. Synthesized water-dispersible polymer-covalent organic framework nanocomposites are integrated via the assembly of PEG-modified monofunctional curcumin derivatives and amine-functionalized covalent organic frameworks for in vitro and in vivo drug delivery. The smart delivery system exhibits an efficient targeting strategy for cancer therapy and also demonstrates an important promise on the improvement of a smart system for cancer cell-/stem cell-targeted drug delivery.

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Author information

Authors and Affiliations

  1. Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, Iran

    Sadegh Ghorbanzade & Seyed Morteza Naghib

Authors
  1. Sadegh Ghorbanzade
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  2. Seyed Morteza Naghib
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Corresponding author

Correspondence to Seyed Morteza Naghib .

Editor information

Editors and Affiliations

  1. Ottawa, ON, Canada

    Kursad Turksen

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Ghorbanzade, S., Naghib, S.M. (2019). Nanoscaled Materials for Drug Delivery into Cells/Stem Cells. In: Turksen, K. (eds) Stem Cell Nanotechnology. Methods in Molecular Biology, vol 2125. Humana, New York, NY. https://doi.org/10.1007/7651_2019_268

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  • DOI: https://doi.org/10.1007/7651_2019_268

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0359-8

  • Online ISBN: 978-1-0716-0360-4

  • eBook Packages: Springer Protocols

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