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Synthesis of 1,2-Disubstituted Cyclopentadienes and Their Application

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Metallocenes in Regio- and Stereoselective Synthesis

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 74))

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Abstract

Cyclopentadiene and its substituted congeners have played an important role in organic chemistry since their discovery. Cyclopentadienyl and substituted cyclopentadienyl anions constitute currently a very important class of ligands for transition metal compounds. Cyclopentadienyl ligands in the respective metallocene complexes show usually high chemical inertness and stability. This property makes the metallocenes popular and indispensable catalysts in a plethora of organic transformations. This review focuses on development of synthetic pathways for preparation of selectively 1,2-disubstituted cyclopentadienes and their conversion to a wide variety of metallocenes. Application of 1,2-disubstituted metallocenes in catalytic processes is mentioned as well.

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Acknowledgment

The authors would like to thank Dr. Timothée Cadart for his useful comments during the last stages of the manuscript preparation.

Author information

Authors and Affiliations

  1. Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Zagreb, Croatia

    Nikola Topolovčan

  2. Department of Organic Chemistry, Faculty of Science, Charles University, Praha 2, Czech Republic

    Martin Kotora

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  1. Nikola Topolovčan
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  2. Martin Kotora
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Corresponding author

Correspondence to Martin Kotora .

Editor information

Editors and Affiliations

  1. Institute of Catalysis, Johannes Kepler University Linz, Linz, Oberösterreich, Austria

    Marko Hapke

  2. Department of Organic Chemistry, Charles University, Faculty of Science, Praha 2, Czech Republic

    Martin Kotora

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Topolovčan, N., Kotora, M. (2023). Synthesis of 1,2-Disubstituted Cyclopentadienes and Their Application. In: Hapke, M., Kotora, M. (eds) Metallocenes in Regio- and Stereoselective Synthesis. Topics in Organometallic Chemistry, vol 74. Springer, Cham. https://doi.org/10.1007/3418_2023_106

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