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Carboxymethyl Chitosan-Based Derivatives in Diagnosis and Targeting

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Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications

Part of the book series: Advances in Polymer Science ((POLYMER,volume 292))

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Abstract

Carboxymethyl chitosan (CMC), a derivative of chitosan, has turned into one of the most favorable biopolymers for the development of targeted drug delivery systems, earlier diagnosis of disease, tissue engineering, wound healing materials, regenerative medicine, and many other formulations for biomedical applications in the past few decades. CMC has shown many desired characteristics such as pH sensitivity, biocompatibility, biodegradability, enhanced aqueous solubility, and numerous other exceptional physicochemical and biological properties. More impressively, CMC-based derivatives can load hydrophobic drugs and other functional materials more effectively for tumor-targeted drug delivery as well as bioimaging and diagnosis of various diseases. This chapter gives a comprehensive review of the recent development of CMC-based formulations as targeted drug delivery systems, diagnosing and imaging agents.

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Author information

Authors and Affiliations

  1. Department of Chemistry, Hindustan Institute of Technology and Science, Chennai, India

    Kiran Joy, D. Sathya Seeli & M. Prabaharan

Authors
  1. Kiran Joy
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  2. D. Sathya Seeli
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  3. M. Prabaharan
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Editor information

Editors and Affiliations

  1. Centre for Nanosciences and Molecular Medicine, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham (University), Kochi, Kerala, India

    R. Jayakumar

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© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Joy, K., Sathya Seeli, D., Prabaharan, M. (2023). Carboxymethyl Chitosan-Based Derivatives in Diagnosis and Targeting. In: Jayakumar, R. (eds) Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications. Advances in Polymer Science, vol 292. Springer, Cham. https://doi.org/10.1007/12_2023_155

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