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Arc welding of steels and pulmonary fibrosis

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Abstract

This paper summarises the increasing epidemiological and experimental evidence of the causal link between exposure to high concentrations of welding fume exposure for prolonged periods of time and the subsequent development of pulmonary fibrosis in a relatively small number of people. It is not yet clear which components of welding fume or gases are the cause, but the most likely culprits are the soluble transition metals which may cause the formation of free radicals. The most likely work scenario leading to pulmonary fibrosis due to welding fume is of high fume exposure, without effective local extraction and respiratory protection, in confined spaces for long periods of time. Avoidance of high exposures for long periods of time is required to prevent this condition. For clarity, the term “pulmonary fibrosis due to prolonged exposure to welding fume at high concentration” is suggested when there is shown to be a causal link in an individual, and we recommend that the terms siderofibrosis and arc welder’s lung are abandoned.

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References

  1. Cosgrove MP (2015) Arc welding and airway disease. Weld World 59:1–7

    Article  Google Scholar 

  2. Nagelschmidt G (1960) The relation between lung dust and lung pathology in pneumoconiosis. Br J Ind Med 17:247–59

    Google Scholar 

  3. Kelleher P, Pacheco K, Newman LS (2000) Inorganic dust pneumonias: the metal-related parenchymal disorders. Environ Health Perspect 108(Suppl 4):685–96

    Article  Google Scholar 

  4. Nemery B (1990) Metal toxicity and the respiratory tract. Eur Respir J 3(2):202–19

    Google Scholar 

  5. Yoshida T, Ohnuma A, Horiuchi H, Harada T (2011) Pulmonary fibrosis in response to environmental cues and molecular targets involved in its pathogenesis. J Toxicol Pathol 24(1):9–24

    Article  Google Scholar 

  6. Doig AT, McLaughlin AIG.: X-ray appearances of the lungs of electric arc welders. Lancet 1936;i:771–5.

  7. Enzer N, Sander OA (1938) Chronic lung changes in electric arc welders. J Ind Hyg 20:333

    Google Scholar 

  8. Harding HE, McLaughlin AIG, Doig AT (1958) Clinical, radiographic, and pathological studies of the lungs of electric-arc and oxyacetylene welders. Lancet 2(7043):394–9

    Article  Google Scholar 

  9. Harding HE, Grout JL, Davies TA (1947) The experimental production of X-ray shadows in the lungs by inhalation of industrial dusts; iron oxide. Br J Ind Med 4(4):223, 232

    Google Scholar 

  10. Doig AT, Challen PJ (1964) Respiratory hazards in welding. Ann Occup Hyg 7:223–31

    Article  Google Scholar 

  11. Schuler P, Maturana V, Cruze E, Guijon C, Vasquez A, Valenzuela A, Silvar R (1962) Arc welder’s pulmonary siderosis. J Occup Med 4:353–8

    Article  Google Scholar 

  12. Beaumont JJ, Weiss NS (1980) Mortality of welders, shipfitters, and other metal trades workers in boilermakers Local No. 104, AFL-CIO. Am J Epidemiol 112(6):775–86

    Google Scholar 

  13. Sjogren B (1980) A retrospective cohort study of mortality among stainless steel welders. Scand J Work Environ Health 6(3):197–200

    Article  Google Scholar 

  14. Polednak AP (1981) Mortality among welders, including a group exposed to nickel oxides. Arch Environ Health 36(5):235–42

    Article  Google Scholar 

  15. Newhouse ML, Oakes D, Woolley AJ (1985) Mortality of welders and other craftsmen at a shipyard in NE England. Br J Ind Med 42(6):406–10

    Google Scholar 

  16. Moulin JJ, Wild P, Haguenoer JM, Faucon D, De GR, Mur JM, Mereau M, Gary Y, Toamain JP, Birembaut Y (1993) A mortality study among mild steel and stainless steel welders. Br J Ind Med 50(3):234–43

    Google Scholar 

  17. Steenland K (2002) Ten-year update on mortality among mild-steel welders. Scand J Work Environ Health 28(3):163–7

    Article  Google Scholar 

  18. Zober A, Kaduk B, Schaller KH (1983) Lungenfibrose eines Elektroschweißers. Kasuistik und versicherungsrechtlichte Bewertungskriterien [Pulmonary fibrosis in an electric welder—case report and legal criteria]. Zentralbl Arbeitsmed Arbeitsschutz Prophyl Ergonomie 33(4):116–20

    Google Scholar 

  19. Zober A (1981) Symptome und Befunde am bronchopulmonalen System bei Elektroschweißern. 2. Mitteilung: Lungenfibrosen. [Symptoms and findings at the bronchopulmonary system of electric arc welders. II. Communication: pulmonary fibrosis]. Zentralbl Bakteriol Mikrobiol Hyg B 173(1–2):120–48

    Google Scholar 

  20. Sano T (1963) Pathology and pathogenesis of pneumoconiosis. Acta Pathol Jpn 13:77–93

    Google Scholar 

  21. Takigawa T, Kishimoto T, Nabe M, Nishide T, Wang DH, Seki A, Uchida G, Kira S (2002) The current state of workers’ pneumoconiosis in relationship to dusty working environments in Okayama Prefecture. Japan Acta Med Okayama 56(6):303–8

    Google Scholar 

  22. Slepicka J, Kadlec K, Tesar Z, Skoda V, Mirejovsky P (1970) Beitrag zur Problematik der Elektroschweißerpneumokoniose [Problems of electric welder’s pneumoconiosis.]. Int Arch Arbeitsmed 27(3):257–80

    Article  Google Scholar 

  23. Marek K, Starzynski Z (1994) Pneumoconioses in Poland. Int J Occup Med Environ Health 7(1):13–21

    Google Scholar 

  24. Charr R (1953) Respiratory disorders among welders. J Am Med Assoc 152(16):1520–2

    Article  Google Scholar 

  25. Charr R (1954) Nontuberculous pulmonary disease: respiratory disorders among welders. Trans Annu Meet Natl Tuberc Assoc 96(50th Meeting):208–11

    Google Scholar 

  26. Charr R (1955) Respiratory disorders among welders. Am Rev Tuberc 71(6):877–84

    Google Scholar 

  27. Charr R (1956) Pulmonary changes in welders: a report of three cases. Ann Intern Med 44(4):806–12

    Article  Google Scholar 

  28. Bundesministerium für Arbeit und Soziales (BMAS) [Federal Ministry of Labour and Social Affaires]: Wissenschaftliche Begründung zur Berufskrankheit Nummer 4115. Lungenfibrose durch extreme und langjärige Einwirkung von Schweißrauchen und Schweißgasen - (Siderofibrose) [Scientific Rationale of Occupational Disease No. 4115. Lung fibrosis due to extreme prolonged exposure to welding fume and gases]. Bek. des BMAS [Notification of the BMAS] vom 1.September 2006 4-45222-4113. Bundesarbeitsblatt 2006 Oct;35–67

  29. Hicks R, Al-Shamma KJ, Lam HF, Hewitt PJ (1983) An investigation of fibrogenic and other toxic effects of arc-welding fume particles deposited in the rat lung. J Appl Toxicol 3(6):297–306

    Article  Google Scholar 

  30. Kalliomaki PL, Hyvarinen HK, Aitio A, Lakoma EL, Kalliomaki K (1986) Kinetics of the metal components of intratracheally instilled stainless steel welding fume suspensions in rats. Br J Ind Med 43(2):112–9

    Google Scholar 

  31. Antonini JM, Krishna Murthy GG, Rogers RA, Albert R, Ulrich GD, Brain JD (1996) Pneumotoxicity and pulmonary clearance of different welding fumes after intratracheal instillation in the rat. Toxicol Appl Pharmacol 140(1):188–99

    Article  Google Scholar 

  32. Antonini JM, Clarke RW, Krishna Murthy GG, Sreekanthan P, Jenkins N, Eagar TW, Brain JD (1998) Freshly generated stainless steel welding fume induces greater lung inflammation in rats as compared to aged fume. Toxicol Lett 98(1–2):77–86

    Article  Google Scholar 

  33. Antonini JM, Taylor MD, Millecchia L, Bebout AR, Roberts JR (2004) Suppression in lung defense responses after bacterial infection in rats pretreated with different welding fumes. Toxicol Appl Pharmacol 200(3):206–18

    Article  Google Scholar 

  34. McNeilly JD, Jimenez LA, Clay MF, MacNee W, Howe A, Heal MR, Beverland IJ, Donaldson K (2005) Soluble transition metals in welding fumes cause inflammation via activation of NF-kappaB and AP-1. Toxicol Lett 158(2):152–7

    Article  Google Scholar 

  35. Kalliomaki PL, Tuomisaari M, Lakomaa EL, Kalliomaki K, Kivela R (1983) Retention and clearance of stainless steel shieldgas welding fumes in rat lungs. Am Ind Hyg Assoc J 44(9):649–54

    Article  Google Scholar 

  36. Kalliomaki PL, Lakomaa E, Kalliomaki K, Kiilunen M, Kivela R, Vaaranen V (1983) Stainless steel manual metal arc welding fumes in rats. Br J Ind Med 40(2):229–34

    Google Scholar 

  37. Taylor MD, Roberts JR, Leonard SS, Shi X, Antonini JM (2003) Effects of welding fumes of differing composition and solubility on free radical production and acute lung injury and inflammation in rats. Toxicol Sci 75(1):181–91

    Article  Google Scholar 

  38. Antonini JM, Taylor MD, Zimmer AT, Roberts JR (2004) Pulmonary responses to welding fumes: role of metal constituents. J Toxicol Environ Health A 67(3):233–49

    Article  Google Scholar 

  39. Antonini JM, Stone S, Roberts JR, Chen B, Schwegler-Berry D, Afshari AA, Frazer DG (2007) Effect of short-term stainless steel welding fume inhalation exposure on lung inflammation, injury, and defense responses in rats. Toxicol Appl Pharmacol 223(3):234–45

    Article  Google Scholar 

  40. Leonard SS, Chen BT, Stone SG, Schwegler-Berry D, Kenyon AJ, Frazer D, Antonini JM (2010) Comparison of stainless and mild steel welding fumes in generation of reactive oxygen species. Part Fibre Toxicol 7:32

    Article  Google Scholar 

  41. Antonini JM, Roberts JR, Stone S, Chen BT, Schwegler-Berry D, Chapman R, Zeidler-Erdely PC, Andrews RN, Frazer DG (2010) Persistence of deposited metals in the lungs after stainless steel and mild steel welding fume inhalation in rats. Arch Toxicol 6

  42. Antonini JM, Lawryk NJ, Murthy GG, Brain JD (1999) Effect of welding fume solubility on lung macrophage viability and function in vitro. J Toxicol Environ Health A 58(6):343–63

    Article  Google Scholar 

  43. Stern RM, Pigott GH (1983) In vitro RPM fibrogenic potential assay of welding fumes. Environ Health Perspect 51:231–6

    Article  Google Scholar 

  44. Solano-Lopez C, Zeidler-Erdely PC, Hubbs AF, Reynolds SH, Roberts JR, Taylor MD, Young SH, Castranova V, Antonini JM (2006) Welding fume exposure and associated inflammatory and hyperplastic changes in the lungs of tumor susceptible a/j mice. Toxicol Pathol 34(4):364–72

    Article  Google Scholar 

  45. Sung JH, Choi BG, Maeng SH, Kim SJ, Chung YH, Han JH, Song KS, Lee YH, Cho YB, Cho MH, Kim KJ, Hyun JS, Yu IJ (2004) Recovery from welding-fume-exposure-induced lung fibrosis and pulmonary function changes in sprague dawley rats. Toxicol Sci 82(2):608–13

    Article  Google Scholar 

  46. Antonini JM, Roberts JR, Chapman RS, Soukup JM, Ghio AJ, Sriram K (2010) Pulmonary toxicity and extrapulmonary tissue distribution of metals after repeated exposure to different welding fumes. Inhal Toxicol 22(10):805–16

    Article  Google Scholar 

  47. Yu IJ, Song KS, Chang HK, Han JH, Kim KJ, Chung YH, Maeng SH, Park SH, Han KT, Chung KH, Chung HK (2001) Lung fibrosis in Sprague–Dawley rats, induced by exposure to manual metal arc-stainless steel welding fumes. Toxicol Sci 63(1):99–106

    Article  Google Scholar 

  48. Attfield MD, Ross DS (1978) Radiological abnormalities in electric-arc welders. Br J Ind Med 35(2):117–22

    Google Scholar 

  49. Stern RM (1981) Process-dependent risk of delayed health effects for welders. Environ Health Perspect 41:235–53

    Article  Google Scholar 

  50. Ekici A, Bilgili Y, Ekici M, Unal B, Akin A, Erdal H, Arslan M, Kocyigit P (2006) High-resolution computed tomography findings in arc-welders. Turkish Respiratory J 7(2):52–5

    Google Scholar 

  51. Tutkun E, Abusoglu S, Yilmaz H, Gunduzoz M, Evcik E, Ozis TN, Keskinkilic B, Unlu A (2014) Farewell to an old friend: chest X-ray vs high-resolution computed tomography in welders’ lung disease. Clin Respir J 8(2):220–4

    Article  Google Scholar 

  52. Han D, Goo JM, Im JG, Lee KS, Paek DM, Park SH (2000) Thin-section CT findings of arc-welders’ pneumoconiosis. Korean J Radiol 1(2):79–83

    Article  Google Scholar 

  53. Yoshii C, Matsuyama T, Takazawa A, Ito T, Yatera K, Hayashi T, Imanaga T, Kido M (2002) Welder’s pneumoconiosis: diagnostic usefulness of high-resolution computed tomography and ferritin determinations in bronchoalveolar lavage fluid. Intern Med 41(12):1111–7

    Article  Google Scholar 

  54. Akira M (1995) Uncommon pneumoconioses: CT and pathologic findings. Radiology 197(2):403–9

    Article  Google Scholar 

  55. Akira M (2002) High-resolution CT in the evaluation of occupational and environmental disease. Radiol Clin North Am 40(1):43–59

    Article  Google Scholar 

  56. Mann BT, Lecutier ER (1957) Arc-welders' lung. Br Med J 2(5050):921–2

    Article  Google Scholar 

  57. Friede E, Rachow DO (1961) Symptomatic pulmonary disease in arc welders. Ann Intern Med 54:121–7

    Article  Google Scholar 

  58. Angervall L, Hansson G, Rockert H (1960) Pulmonary siderosis in electrical welder. A note on pathological appearances. Acta Pathol Microbiol Scand 49:373–92

    Article  Google Scholar 

  59. Fabre M, Marais M, Ladouch A, Paillas J, Blanchon P (1976) quillard J.: La pneumoconiose des soudeurs a l'arc. Arch Anat Cytol Pathol 24(6):481–5

    Google Scholar 

  60. Guidotti TL, Abraham JL, DeNee PB, Smith JR (1978) Arc welders’ pneumoconiosis: application of advanced scanning electron microscopy. Arch Environ Health 33(3):117–24

    Article  Google Scholar 

  61. Kalliomaki PL, Sutinen S, Kelha V, Lakomaa E, Sortti V, Sutinen S (1979) Amount and distribution of fume contaminants in the lungs of an arc welder post mortem. Br J Ind Med 36(3):224–30

    Google Scholar 

  62. Barth J, Holtmann B, Muller KM (1986) Alveolar-septale Fibrose und systemische Eisenbelastung bei einem Schweißer [Interstitial pulmonary siderofibrosis and increased systemic iron level in an arc welder]. Atemw-Lungenkrkh 7:290–3

    Google Scholar 

  63. Wagner U, Meerbach W, Fischer W, Otto J, Jahn R, Schneider WD (1990) Kasuistischer Beitrag zur Schweißerlunge [A case report of welder’s lung]. Z Erkr Atmungsorgane 174(2):149–54

    Google Scholar 

  64. Steurich F, Feyerabend R (1997) Sidero-Fibrose der Lungen nach jahrzehntelangem Elektroschweißen [Sidero-fibrosis of the lungs after decades of arc welding]. Pneumologie 51(6):545–9

    Google Scholar 

  65. Yamada G, Igarashi T, Sonoda H, Morita S, Suzuki K, Yoshida Y, Abe S (1998) Use of bronchopulmonary lavage for eliminating inhaled fume particles from a patient with arc welder's lung. Intern Med 37(11):962–4

    Article  Google Scholar 

  66. Scharrer E, Bittmann I, Behr J, Nowak D (2003) Siderofibrose, atypische Mykobacteriose und Lungentransplantation bei einem Behälterschweißer [Siderofibrosis, MOTT, and lung transplantation in a worker welding in confined spaces]. Pneumologie 57(1):15–8

    Article  Google Scholar 

  67. Ishida Y, Sera K, Ohta K, Kageshita T (2003) A case of rapid development of arc welder’s lung during the course of a year. Nihon Kokyuki Gakkai Zasshi 41(5):351–5

    Google Scholar 

  68. Mendez JL, Rabatin JT, Cassivi SD (2004) Bilateral pulmonary nodules in a welder with a 90 pack year history of smoking. Chest 996S

  69. Fidan F, Esme H, Unlu M, Acar M, Albayrak R, Dilek FH (2005) Welder’s lung associated with pneumothorax. J Thorac Imaging 20(2):120–2

    Article  Google Scholar 

  70. McCormick LM, Goddard M, Mahadeva R (2008) Pulmonary fibrosis secondary to siderosis causing symptomatic respiratory disease: a case report. J Med Case Rep 2:257

    Article  Google Scholar 

  71. Khalid I, Khalid TJ, Jennings JH (2009) A welder with pneumosiderosis: a case report. Cases J 2:6639

    Article  Google Scholar 

  72. Modrykamien A, Christie H, Farver C, Ashton RW (2009) A 38-year-old welder with dyspnea and iron overload. Chest 136(1):310–3

    Article  Google Scholar 

  73. Roshan R, Guptal M, Kulshrestha R, Menon B, Chhabra SK (2012) Combined pulmonary fibrosis and emphysema in a welder. Monaldi Arch Chest Dis 77(1):26–8

    Google Scholar 

  74. Antonini JM, Roberts JR, Schwegler-Berry D, Mercer RR.: Comparative Microscopic Study of Human and Rat Lungs After Overexposure to Welding Fume. Ann Occup Hyg 2013 Jun 24

  75. Schuler P (1962) Arc welder’s pulmonary siderosis. J Occup Med 4:353–8

    Article  Google Scholar 

  76. Einbrodt HJ, Maass W, Josten HG, Stecher W (1971) Untersuchungen über die Lungenveränderungen bei Elektroschweißern [Studies of pulmonary changes in electric welding workers]. Öffentl Gesundheitswes 33(5):286–99

    Google Scholar 

  77. Irmscher G, Beck B, Ahlendorf W, Anspach M, Konetzke G, Ludwig V, Sturm W (1975) Erfahrungen bei der Begutachtung von fraglichen Lungenfibrosen durch Einwirkung von Schweißrauchen [Experience gathered in assessing doubtful fibrosis of the lung caused by welding fume]. Z Gesamte Hyg 21(7):562–6

    Google Scholar 

  78. Morgan WK (1962) Arc-welders’ lung complicated by conglomeration. Am Rev Respir Dis 85:570–5

    Google Scholar 

  79. Kinoshita M, Hanzawa S, Momiki S, Sasaki K, Hashizume I, Kasamatsu N, Nakamura A, Shirai T, Ozawa T (1997) A case of pneumoconiosis (welder’s lung) suspected to be lung cancer. Nihon Kyobu Shikkan Gakkai Zasshi 35(10):1124–31

    Google Scholar 

  80. Yokoyama T, Aoshima M, Kurakawa E, P J, Kasuga I, Minemura K, Ohyashiki K (2005) A case of arc welder’s lung with ground-glass opacities and progressive massive fibrosis. Nihon Kokyuki Gakkai Zasshi 43(5):302–7

    Google Scholar 

  81. Ji C, Chen G, Cai HR, Meng FQ, Chen YB, Guo LC, Huang JA, Ling CH (2012) An unusual case of Welder’s siderosis with local massive fibrosis: a case report. Chin Med J (Engl ) 125(3):552–4

    Google Scholar 

  82. Morgan KCM, Kerr HD (1963) Pathologic and physiologic studies of welder’s siderosis. Ann Intern Med 55:293–304

    Article  Google Scholar 

  83. Stettler LE, Groth DH, MacKay GR (1977) Identification of stainless steel welding fume particulates in human lung and environmental samples using electron probe microanalysis. Am Ind Hyg Assoc J 38(2):76–82

    Article  Google Scholar 

  84. Burger A, Philippou X.: Electronenmikroskopische Befunde zur Pathogenese der sogenannten Schweißerlunge. [Electron microscopic findings with respect to the pathogenesis of so-called welder's lung]. Berichte Pathologie 1977;104:447.

  85. Stern RM, Pigott GH, Abraham JL (1983) Fibrogenic potential of welding fumes. J Appl Toxicol 3(1):18–30

    Article  Google Scholar 

  86. Morgenroth K, Verhagen-Schröter G (1984) Licht - und electronenmikroskopische Untersuchungen und energiedispersive Röntgenmikroanalyse an Biopsiematerial zur Pathogenese der Schweißerlunge [Light and electron microscopic examination and energy dispersive radiologic microanalysis of biopsy specimens for the pathogenesis of arc-welder’s lung]. Atemw-Lungenkrkh 10:451–6

    Google Scholar 

  87. Stanulla H, Liebetrau G (1984) Die Elektroschweißerlunge [Electric welder’s lung]. Prax Klin Pneumol 38(1):14–8

    Google Scholar 

  88. Funahashi A, Schlueter DP, Pintar K, Bemis EL, Siegesmund KA (1988) Welders' pneumoconiosis: tissue elemental microanalysis by energy dispersive x ray analysis. Br J Ind Med 45(1):14–8

    Google Scholar 

  89. Radenbach D, Nowak D, Jörres R, Magnussen H (1995) Untersuchungsergsergebnisse bei 30 symptomatischen Schweißern [Medical findings in 30 symptomatic welders]. Atemw-Lungenkrkh 21:105–11

    Google Scholar 

  90. Rösler J, Morgenroth K, Müller KM, Woitowitz HJ.: Lungenfibrosen nach langjähriger Einwirkung von Schweißrauchen [Lung fibroses after long-time exposure to welding fumes]. In: Schiele R, Beyer B, Petrovitch A (Hrsg) [eds]: Verh Dtsch Ges Arbeitsmed Umweltmed. [Proceedings of the Annual Assembly of the German Society of Occupational Medicine and Environmental Medicine]. 1995;35:285–8, Rindt-Druck [Rindt-Publishers], Fulda.

  91. Müller KM, Verhoff MA (2000) Graduierung von Sideropneumokoniosen [Gradation of sideropneumoconiosis]. Pneumologie 54(8):315–7

    Article  Google Scholar 

  92. Verhoff MA, Müller KM (2000) Sideroelastose der Pulmonalgefäße nach Schweißrauchexposition [Sideroelastosis of pulmonary vessels after welder dust exposure]. Pathologe 21(3):229–33

    Article  Google Scholar 

  93. Buerke U, Schneider J, Müller KM, Woitowitz HJ (2003) Schweißerlungenfibrose: Begründung fuer die Aufnahme als neue Berufskrankheit [Interstitial pulmonary siderofibrosis: requirements for acceptance as new occupational disease]. Pneumologie 57(1):9–14

    Article  Google Scholar 

  94. Doherty MJ, Healy M, Richardson SG, Fisher NC (2004) Total body iron overload in welder’s siderosis. Occup Environ Med 61(1):82–5

    Google Scholar 

  95. Buerke U, Schneider J, Rosler J, Woitowitz HJ (2002) Interstitial pulmonary fibrosis after severe exposure to welding fumes. Am J Ind Med 41(4):259–68

    Article  Google Scholar 

  96. Cosgrove MP (2015) Pulmonary fibrosis and exposure to steel welding fume. Occup Med (Lond) 65:706--712

  97. Scott J, Johnston I, Britton J (1990) What causes cryptogenic fibrosing alveolitis? A case–control study of environmental exposure to dust. BMJ 301(6759):1015–7

    Article  Google Scholar 

  98. Iwai K, Mori T, Yamada N, Yamaguchi M, Hosoda Y (1994) Idiopathic pulmonary fibrosis. Epidemiologic approaches to occupational exposure. Am J Respir Crit Care Med 150(3):670–5

    Article  Google Scholar 

  99. Baumgartner KB, Samet JM, Coultas DB, Stidley CA, Hunt WC, Colby TV, Waldron JA (2000) Occupational and environmental risk factors for idiopathic pulmonary fibrosis: a multicenter case–control study. Collaborating Centers Am J Epidemiol 152(4):307–15

    Article  Google Scholar 

  100. Miyake Y, Sasaki S, Yokoyama T, Chida K, Azuma A, Suda T, Kudoh S, Sakamoto N, Okamoto K, Kobashi G, Washio M, Inaba Y, Tanaka H (2005) Occupational and environmental factors and idiopathic pulmonary fibrosis in Japan. Ann Occup Hyg 49(3):259–65

    Article  Google Scholar 

  101. Taskar VS, Coultas DB (2006) Is idiopathic pulmonary fibrosis an environmental disease? Proc Am Thorac Soc 3(4):293–8

    Article  Google Scholar 

  102. Pinheiro GA, Antao VC, Wood JM, Wassell JT (2008) Occupational risks for idiopathic pulmonary fibrosis mortality in the United States. Int J Occup Environ Health 14(2):117–23

    Article  Google Scholar 

  103. Fireman EM, Lerman Y, Ben MM, Ganor E, Kramer MR (2007) Redefining idiopathic interstitial lung disease into occupational lung diseases by analysis of chemical composition of inhaled dust particles in induced sputum and/or lung biopsy specimens. Toxicol Ind Health 23(10):607–15

    Article  Google Scholar 

  104. Abraham JL, Hertzberg MA (1981) Inorganic particulates associated with desquamative interstitial pneumonia. Chest 80(1 Suppl):67–70

    Article  Google Scholar 

  105. Nasr MR, Savici D, Tudor L, Abou AD, Newman N, Abraham JL (2006) Inorganic dust exposure causes pulmonary fibrosis in smokers: analysis using light microscopy, scanning electron microscopy, and energy dispersive X-ray spectroscopy. Arch Environ Occup Health 61(2):53–60

    Article  Google Scholar 

  106. Godbert B, Wissler MP, Vignaud JM (2013) Desquamative interstitial pneumonia: an analytic review with an emphasis on aetiology. Eur Respir Rev 22(128):117–23

    Article  Google Scholar 

  107. Monso E, Tura JM, Marsal M, Morell F, Pujadas J, Morera J (1990) Mineralogical microanalysis of idiopathic pulmonary fibrosis. Arch Environ Health 45(3):185–8

    Article  Google Scholar 

  108. Monso E, Tura JM, Pujadas J, Morell F, Ruiz J, Morera J (1991) Lung dust content in idiopathic pulmonary fibrosis: a study with scanning electron microscopy and energy dispersive x ray analysis. Br J Ind Med 48(5):327–31

    Google Scholar 

  109. Sander OA (1944) Further observations on lung changes in electric arc welders. J Ind Hyg Toxicol 26:79–85

    Google Scholar 

  110. Meyer EC, Kratzinger SF, Miller WH (1967) Pulmonary fibrosis in an arc welder. Arch Environ Health 15(4):462–9

    Article  Google Scholar 

  111. Palmer KT, Cosgrove MP (2012) Vaccinating welders against pneumonia. Occup Med (Lond) 62(5):325–30

    Article  Google Scholar 

  112. Wong A, Marrie TJ, Garg S, Kellner JD, Tyrrell GJ (2010) Welders are at increased risk for invasive pneumococcal disease. Int J Infect Dis 14(9):e796–e799

    Article  Google Scholar 

  113. Palmer KT, Poole J, Ayres JG, Mann J, Burge PS, Coggon D (2003) Exposure to metal fume and infectious pneumonia. Am J Epidemiol 157(3):227–33

    Article  Google Scholar 

  114. Kendzia B, Behrens T, Jockel KH, Siemiatycki J, Kromhout H, Vermeulen R, Peters S, Van GR, Olsson A, Bruske I, Wichmann HE, Stucker I, Guida F, Tardon A, Merletti F, Mirabelli D, Richiardi L, Pohlabeln H, Ahrens W, Landi MT, Caporaso N, Consonni D, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Gustavsson P, Marcus M, Fabianova E, Pearce N, Tse LA, Yu IT, Rudnai P, Bencko V, Janout V, Mates D, Foretova L, Forastiere F, McLaughlin J, Demers P, Bueno-de-Mesquita B, Boffetta P, Schuz J, Straif K, Pesch B, Bruning T (2013) Welding and lung cancer in a pooled analysis of case–control studies. Am J Epidemiol 178(10):1513–25

    Article  Google Scholar 

  115. Ambroise D, Wild P, Moulin JJ (2006) Update of a meta-analysis on lung cancer and welding. Scand J Work Environ Health 32(1):22–31

    Article  Google Scholar 

  116. Moulin JJ (1997) A meta-analysis of epidemiologic studies of lung cancer in welders. Scand J Work Environ Health 23(2):104–13

    Article  Google Scholar 

  117. Yamada Y, Terada J, Tatsumi K, Kono C, Tanno M, Takemura T, Yamaguchi T (2013) Respiratory bronchiolitis and lung carcinoma. Respir Investig 51(3):184–90

    Article  Google Scholar 

  118. Harris JM, Johnston IDA, Rudd R, Newman Taylor AJ, Cullinan P (2010) Cryptogenic fibrosing alveolitis and lung cancer: the BTS study. Thorax 65(1):70–76

    Article  Google Scholar 

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Acknowledgements

The authors would like to thank all the members of Commission VIII of the International Institute of Welding and Paul Cullinan for their tremendous support, advice and cooperation in developing and writing this document. We would also like to thank Paul Stevenson and the British Library for their help with undertaking the literature search and obtaining the papers.

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Correspondence to Martin Cosgrove.

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Recommended for publication by Commission VIII - Health, Safety, and Environment

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Cosgrove, M., Zschiesche, W. Arc welding of steels and pulmonary fibrosis. Weld World 60, 191–199 (2016). https://doi.org/10.1007/s40194-015-0283-7

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