Résumé
Le diabète gestationnel (DG) peut être un diabète de type 2 (DT2) méconnu, découvert pendant la grossesse ou une anomalie de la tolérance glucidique réellement apparue en cours de grossesse dont les pronostics sont différents. Il existe une corrélation linéaire et positive entre l’hyperglycémie maternelle et les complications périnatales. L’obésité maternelle est un facteur de risque de complications surajouté et indépendant de l’hyperglycémie
Abstract
Gestational diabetes mellitus might be either an unknown type 2 diabetes mellitus diagnosed during pregnancy or a glucose tolerance impairment appearing during pregnancy; these two conditions have different prognosis. There is a positive linear correlation between maternal hyperglycemia and perinatal complications. Maternal obesity is an independent risk factor for perinatal complications.
Références
HAPO Study Cooperative Research Group (2008) Hyperglycemia and adverse pregnancy outcomes. N Engl J Med 358: 1991–2002
Charles MA, Eschwège E, Basdevant A (2008) Monitoring the obesity epidemic in France: the Obepi surveys 1997–2006. Obesity 16:2182–2186
Torloni MR, Betran AP, Horta BL, et al (2009) Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis. Obes Rev 10:194–203
Kim SY, England L, Wilson HG, et al (2010) Percentage of gestational diabetes mellitus attributable to overweight and obesity. Am J Public Health 100:1047–1052
Burke AE, Bennett WL, Jamshidi RM, et al (2010) Reduced incidence of gestational diabetes with bariatric surgery. J Am Coll Surg 211:169–175
Kim C, Newton KM, Knopp RH (2002) Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 25:1862–1868
Langer O, Yogev Y, Xenakis EMJ, Brustman L (2005) Overweight and obese in gestational diabetes: the impact on pregnancy outcome. Am J Obstet Gynecol 192:1768–1776
Ray JG, Vermeulen MJ, Shapiro JL, Kenshole AB (2001) Maternal and neonatal outcomes in pregestational and gestational diabetes mellitus, and the influence of maternal obesity and weight gain: the DEPOSIT study. Diabetes Endocrine Pregnancy Outcome Study in Toronto. Q J Med 94:347–356
Jensen DM, Damm P, Sørensen B, et al (2003) Pregnancy outcome and prepregnancy body mass index in 2,459 glucosetolerant Danish women. Am J Obstet Gynecol 189:239–244
O’Brien TE, Ray JG, Chan WS (2003) Maternal body mass index and the risk of preeclampsia: a systematic overview. Epidemiology 14:368–374
HAPO Study Cooperative Research Group (2010) Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) Study: associations with maternal body mass index. BJOG 117:575–584
Correa A, Gilboa SM, Besser LM, et al (2008) Diabetes mellitus and birth defects. Am J Obstet Gynecol 199:237.e1–237.e9
Garcia-Patterson A, Erdozain L, Ginovart G, et al (2004) In human gestational diabetes mellitus congenital malformations are related to pre-pregnancy body mass index and to severity of diabetes. Diabetologia 47:509–514
Mitanchez D (2010) Foetal and neonatal complications in gestational diabetes: perinatal mortality, congenital malformations, macrosomia, shoulder dystocia, birth injuries, neonatal complications. Diabetes Metab 36(6 Pt 2):617–627
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) (2009) Study group: associations with neonatal anthropometrics. Diabetes 58:453–459
Ong KK, Diderholm B, Salzano G, et al (2008) Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers. Diabetes Care 31:2193–2197
Ehrenberg HM, Mercer BM, Catalano PM (2004) The influence of obesity and diabetes on the prevalence of macrosomia. Am J Obstet Gynecol 191:964–968
Cheng YW, Chung JH, Kurbisch-Block I, et al (2008) Gestational weight gain and gestational diabetes mellitus: perinatal outcomes. Obstet Gynecol 112:1015–1022
Jolly M, Sebire N, Harris J, et al (2003) Risk factors for macrosomia and its clinical consequences: a study of 350,311 pregnancies. Obstet Gynecol 111:9–14
Langer O, Yogev Y, Most O, Xenakis EM (2005) Gestational diabetes: the consequences of not treating. Am J Obstet Gynecol 192:989–997
Chu SY, Kim SY, Lau J, Schmid, et al (2007) Maternal obesity and risk of stillbirth: a metaanalysis. Am J Obstet Gynecol 197:223–228
Raatikainen K, Heiskanen N, Heinonen S (2006) Transition from overweight to obesity worsens pregnancy outcome in a BMIdependent manner. Obesity 14:165–171
Cnattingius S, Bergstrom R, Lipworth L, Kramer MS (1998) Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med 338:147–152
Zhang X, Decker A, Platt RW, Kramer MS (2008) How big is too big? The perinatal consequences of fetal macrosomia. Am J Obstet Gynecol 198:517.e1–517.e6
Crowther CA, Hiller JE, Moss JR, et al (2005) for the Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group. N Engl J Med 352:2477–2486
Landon MB, Spong CY, Thom E, et al (2009) A multicenter, randomized trial of treatment for mild gestational diabetes. N Engl J Med 361:1339–1348
Expert consensus on gestational diabetes mellitus (2010) Summary of expert consensus. Diabetes Metab 36(6 Pt 2):695–699
Galtier F (2010) Gestationald diabetes mellitus. Definition, epidemiology, risk factors. Diabetes Metab 36(6 Pt 2):628–651
Beucher G, Viaris de Lesegno B, Dreyfus M (2010) Maternal outcome of gestational diabetes mellitus. Diabetes Metab 36(6 Pt 2):522–537
Hiéronimus S, Le Meaux JP (2010) Relevance of gestational diabetes mellitus screening and comparison of selective with universal strategies. Diabetes Metab 36(6 Pt 2):575–586
Guedj AM (2010) When should screening be performed for gestational diabetes? Diabetes Metab 36(6 Pt 2):652–657
International Association of Diabetes and Pregnancy Study Groups (2010) Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy. Diabetes Care 33:646–682
Cosson E (2010) Diagnostic criteria for gestational diabetes mellitus. Diabetes Metab 36(6 Pt 2):538–548
Jacqueminet S, Jannot-Lamotte MF (2010) Therapeutic management of gestational diabetes. Diabetes Metab 36(6 Pt 2):658–671
Verier-Mine O (2010) Outcomes in women with a history of gestational diabetes. Screening and prevention of type 2 diabetes. Diabetes Metab 36(6 Pt 2):595–616
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Lepercq, J. Diabète gestationnel, surpoids, obésité. Rev. med. perinat. 3, 5–10 (2011). https://doi.org/10.1007/s12611-011-0093-4
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DOI: https://doi.org/10.1007/s12611-011-0093-4