摘要
目的
观察针刺对运动性疲劳大鼠部分生化指标的影响, 探讨针刺抗运动性疲劳的作用机制。
方法
采用4 星期递增游泳训练的方法复制慢性运动性疲劳大鼠模型, 随机分为对照组、模型组、头穴组、体穴组,采用“逆针灸”的方法。观察治疗前后各组大鼠力竭游泳时间、全血乳酸(Lactic Acid, LA)、肌酸激酶(Creatine Kinase, CK)、血尿素氮(Blood Urea Nitrogen, BUN)、血红蛋白(Hemoglobin, Hb)及游离色氨酸/支链氨基酸(free Tryptophan/Branched Chain Amino Acid, F-TRP/BCAA)的变化。
结果
与体穴组相比, 头穴组在提高Hb 水平,降低BUN、LA 水平方面有明显优势(P<0.05)。在降低CK、F-TRP/BCAA 水平方面, 更是明显优于体穴组(P<0.01)。
结论
头穴针刺能够有效改善运动性疲劳大鼠生化指标,同时降低F-TRP/BCAA 水平,抑制5-HT 生成,从而有效地改善大鼠疲劳程度。
Abstract
Objective
To observe the effect of acupuncture on some biochemical parameters in rats with exercise-induced fatigue and to explore the mechanism of acupuncture for exercise fatigue.
Methods
The rat model of chronic exercise-induced fatigue was established by a 4-week increasing swimming training method. The rats were randomly divided into a control group, a model group, a scalp acupoint group, and a body acupoint group. Preventive acupuncture methods were used. Changes of exhaustive swimming time, whole blood lactic acid (LA), creatine kinase (CK), blood urea nitrogen (BUN), hemoglobin (Hb) and free tryptophan/branched chain amino acid (F-TRP/BCAA) of rats in each group before and after treatments were observed.
Results
Compared with the body acupoint group, there were obvious advantages of the scalp point group in increasing Hb levels and lowering BUN and LA levels (P<0.05), as well as in aspects of lowering CK and F-TRP/BCAA levels (P<0.01).
Conclusion
Scalp point acupuncture can improve the biochemical parameters in rats with exercise-induced fatigue, meanwhile, decrease the F-TRP/BCAA level, inhibit the 5-HT producing, and improve the rats’ fatigue consequently.
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Li, Hl., Sun, Yz. Influence of acupuncture on biochemical parameters in exercise-induced fatigue rats. J. Acupunct. Tuina. Sci. 10, 277–280 (2012). https://doi.org/10.1007/s11726-012-0619-4
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DOI: https://doi.org/10.1007/s11726-012-0619-4