Skip to main content
Log in

Sustainable utilization of oil palm wastes for bioactive phytochemicals for the benefit of the oil palm and nutraceutical industries

  • Published:
Phytochemistry Reviews Aims and scope Submit manuscript

Abstract

For a hectare of oil palm plantation, about 21.63 tonnes of biomass comprising 20.43 % empty fruit bunches, 5.09 % palm kernel shells, 11.65 % oil palm trunks, 50.30 % oil palm fronds and 12.53 % palm pressed fibre is produced per year as wastes which keep raising many environmental concerns as most of them are incinerated and dumped at open sites. Oil palm wastes are found to contain phytochemicals which have anti-cancer, antioxidants and other vital biological activities. About 17–65 kg of carotenoids, 0.1–60 kg phenolic compounds, 0.6–39 kg sterols and 4.0–62 kg tocols could be extracted from these wastes which would not only boost the economy but also help improve human health and promote clean environments. This study assesses the phytochemistry of oil palm wastes and their pharmacological activities beneficial to the nutraceutical industry with the view of utilizing oil palm wastes for sustainable development.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Abbreviations

OPB:

Oil palm biomass

OPW:

Oil palm wastes

OPFF:

Oil palm fresh fruit

OPF:

Oil palm fronds

OPT:

Oil palm trunks

OPR:

Oil palm roots

OPL:

Oil palm leaves

PKC:

Palm kernel cake

PPF:

Palm pressed fibre

POME:

Palm oil mill effluent

EFB:

Empty fruit bunches

PKO:

Palm kernel oil

CPO:

Crude palm oil

PKS:

Palm kernel shells

PFAD:

Palm fatty acid distillate

HPLC:

High-performance liquid chromatography

GC-FID:

Gas chromatography with flame ionization detector

GC–MS:

Gas chromatography with mass spectroscopy

TL-C:

Thin-layer chromatography

FTIR-S:

Fourier transform infrared spectroscopy

UV-S:

Ultra violet spectroscopy

LC–MS:

Liquid chromatography with mass spectroscopy

References

  • Abdul Khalil HPS, Siti Alwani M, Mohd Omar AK (2006) Chemical composition, anatomy, lignin distribution and cell wall structure of Malaysian plant waste fibers. Bioresour 1:220–232

    Google Scholar 

  • Abeywardena M, Runnie I, Nizae M et al (2002) Polyphenol-enriched extract of oil palm fronds (Elaeis guineensis) promotes vascular relaxation via endothelium-dependent mechanisms. Asia Pac J Clin Nutr 11:S467–S472

    Article  CAS  PubMed  Google Scholar 

  • Ahmad AL, Chan CY, Abd Shuker SR et al (2009) Isolation of carotenes from palm oil mill effluent and its use as a source of carotene. Desalin Water Treat 7:251–256

    Article  CAS  Google Scholar 

  • Akpan EJ, Usoh IF (2004) Phytochemical screening and effect of aqueous root extract of Raphia hookeri (raffia palm) on metabolic clearance rate of ethanol in rabbits. Biochem 16:37–42

    Google Scholar 

  • Alimon AR (2005) The nutritive value of palm kernel cake for animal feed. Palm Oil Dev 40:12–14

    Google Scholar 

  • Ao X, Zhou TX, Meng QW, Lee JH, Jang HD, Cho JH, Kim IH (2011) Effects of a carbohydrase cocktail supplementation on the growth performance, nutrient digestibility, blood profiles and meat quality in finishing pigs fed palm kernel cake. Livest Sci 137:238–243

    Google Scholar 

  • Ariff Omer M, Hayakawa H, Zahari MW et al (1998) Collaboration between MARDI and JICA Project Publication No. 4

  • Ariffin H, Abdullah N, Umikalsom MS et al (2008) Production of bacterial endoglucanase from pretreated oil palm empty fruit bunch by Bacillus pumilus EB3. J Biosci Bioeng 106:231–236

    Article  CAS  PubMed  Google Scholar 

  • Arvanitoyannis IS, Varzakas T (2008a) Vegetable waste treatment: comparison & critical presentation of methods, and treatment. Crit Rev Food Sci Nutr 48:205–247

    Article  CAS  PubMed  Google Scholar 

  • Arvanitoyannis IS, Varzakas T (2008b) Vegetable waste management: treatment methods and potential uses of treated waste. In: Arvanitoyannis IS (ed) Waste management for the food industries. Elsevier, Amsterdam, pp 703–761

    Chapter  Google Scholar 

  • Baharuddin AS, Razak MNA, Siong HL et al (2010) Isolation and characterization of thermophilic cellulase-producing bacteria from empty fruit bunches-palm oil mill effluent compost. Am J Appl Sci 7:56–62

    Article  CAS  Google Scholar 

  • Basiron Y, Kook Weng C (2004) The oil palm and its sustainability. J Oil Palm Res 16:1–10

    Article  Google Scholar 

  • BCC Research report FOD 025C (2008) The Global Market for Carotenoids

  • Benade AJ (2003) A place for palm fruit oil to eliminate vitamin a deficiency. Asia Pac J Clin Nutr 12:369–372

    CAS  PubMed  Google Scholar 

  • Berry SE, Woodward R, Yeoh C et al (2007) Effect of interesterification of palmitic acid-rich triacylglycerol on postprandial lipid and factor VII response. Lipid 42:315–323

    Article  CAS  Google Scholar 

  • Bhat R, Khalil HPSA, Karim AA (2009) Exploring the antioxidant potential of lignin isolated from black liquor of oil palm waste. J Biol 332:827–831

    CAS  Google Scholar 

  • Birtigh A, Johannsen M, Brunner G et al (1995) Supercritical fluid extraction of oil-palm components. J Supercrit Fluid 8:46–50

    Article  CAS  Google Scholar 

  • Bortolomeazzi R, Cordaro F, Pizzale L et al (2003) Presence of phytosterol oxides in crude vegetable oils and their fate during refining. J Agric Food Chem 51:2394–2401

    Article  CAS  PubMed  Google Scholar 

  • Bravo L (1998) Polyphenols: chemistry, dietary sources, metabolism and nutritional significance. Nutr Rev 56:317–333

    Article  CAS  PubMed  Google Scholar 

  • Bruneton J (1995) Pharmacognosy, phytochemistry, medicinal plants. Lavoisier Publishing, Paris, pp 538–544

    Google Scholar 

  • Budin SB, Othman F, Louis SR et al (2009) The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats. Clinic 64:235–244

    Google Scholar 

  • Chee KL, Ling HK, Ayob MK (2012) Optimization of trypsin-assisted extraction, physic-chemical characterization, nutritional qualities and functionalities of palm kernel cake protein. LWT Food Sci Technol 46:419–427

    Article  CAS  Google Scholar 

  • Chin KL, H’ng PS, Wong LJ et al (2010) Optimization study of ethanolic fermentation from oil palm trunk, rubberwood and mixed hardwood hydrolysates using Saccharomyces cerevisiae. Bioresour Technol 101:3287–3291

    Article  CAS  PubMed  Google Scholar 

  • Chiu MC, de Morais Coutinho C, Gonçalves LAG (2009) Carotenoids concentration of palm oil using membrane technology. Desalin 246:410–413

    Google Scholar 

  • Chong KP, Rossall S, Atong M (2011) HPC fingerprints and in vitro antimicrobial activity of syringic acid, caffeic acid and 4-hydroxybenzoic acid against Ganoderma boninense. J Appl Sci 11:2284–2291

    Article  CAS  Google Scholar 

  • Choo YM, Yap SC, Ong ASH et al (1992) Production of palm oil carotenoids concentrate and its potential application in nutrition. In: Ong ASH, Packer L (eds) Lipid-soluble antioxidants, biochemistry and clinical application. Birkhauser Verlag, Basel, pp 243–253

    Chapter  Google Scholar 

  • Choo YM, Yap SC, Ooi CK et al (1996) Recovered oil from palm-pressed fiber: a good source of natural carotenoids, vitamin E, and sterols. J Am Oil Chem Soc 73:599–602

    Article  CAS  Google Scholar 

  • Choo YM, Ng MH, Ma AN et al (2005) Application of supercritical fluidchromatography in the quantitative analysis of minor components (carotenes, vitamin E, sterols, and squalene) from palm oil. Lipid 40:429–432

    Article  CAS  Google Scholar 

  • Chow MC, Ho CC (2002) Chemical composition of oil droplets from palm oil mill sludge. J Oil Palm Res 14:25–34

    Article  CAS  Google Scholar 

  • Chu BS, Baharin BS, Che Man YB et al (2004) Separation of vitamin E from palm fatty acid distillate using silica: I. Equilibrium of batch adsorption. J Food Eng 62:97–103

    Article  Google Scholar 

  • Chua CSL, Baharin BS, Man YBC et al (2007) Separation of squalene from palm fatty acid distillate using adsorption chromatography. Eur J Lipid Sci Technol 109:1083–1087

    Article  CAS  Google Scholar 

  • Clore JN, Stillman JS, Li J et al (2004) Differential effect of saturated and polyunsaturated fatty acids on hepatic glucose metabolism in humans. Am J Physiol Endocrinol Metab 287:E358–E365

    Article  CAS  PubMed  Google Scholar 

  • De Franca LF, Meireles MAA (2000) Modeling of extraction of carotene and lipids from pressed palm oil (Elaeis guneensis) fibers using supercritical CO2. J Supercrit Fluid 18:35–47

    Article  Google Scholar 

  • Delgado-Vargas F, Jimenez AR, Paredes-Lopez O (2000) Natural pigments: carotenoids, anthocyanins, and betalains–characteristics, biosynthesis, processing, and stability. Crit Rev Food Sci Nutr 40:173–289

    Article  CAS  PubMed  Google Scholar 

  • Diabate S, De Franqueville H, Allou D et al (2009) Phenolic Diversity in the Defense Reaction of the Oil Palm against Vascular Wilt Disease. In: Proceedings of the 2009 international palm oil congress on palm oil: balancing ecologics with economics, Kuala Lumpur, pp 1027–1034

  • Edem DO, Eka OU, Umoh IB (2002) Feeding of red palm oil-supplemented diets to rats may impact positively on vitamin A status. Int J Food Sci Nutr 53:285–291

    Article  CAS  PubMed  Google Scholar 

  • EFSA (European Food Safety Authority) Panel on Dietetic Products, Nutrition and Allergies (NDA) (2010) Scientific Opinion on the substantiation of health claims related to plant sterols and plant stanols and maintenance of normal blood cholesterol concentrations and maintenance of normal prostate size and normal urination pursuant to Article 13(1) of Regulation (EC) No 1924/2006, EFSA 8: 1813

  • Eldahshan O, Ayoub N, Singab A et al (2009) Potential antioxidant phenolic metabolites from doum palm leaves. Afric J Pharm Pharmacol 3:158–164

    CAS  Google Scholar 

  • Enwefa C, Uwajeh R, Oduh M (1992) Some studies on Nigerian palm wine with special reference to yeasts. Acta Biotechnol 12:117–125

    Article  CAS  Google Scholar 

  • Esterhuyse AJ, Toit ED, Rooyen JV (2005) Dietary red palm oil supplementation protects against the consequences of global ischemia in the isolated perfused rat heart. Asia Pac J Clin Nutr 14:340–347

    CAS  PubMed  Google Scholar 

  • Ezieshi EV, Olomu JM (2007) Nutritional evaluation of palm kernel meal types: 1. Proximate composition and metabolizable energy values. Afr J Biotechnol 6:2484–2486

    Google Scholar 

  • Fairhurst TH, Mutert E (1999) Interpretation and management of oil palm leaf analysis data. Better Crop Int 13:48–51

    Google Scholar 

  • Food and Agriculture Organization Statistical (FAOSTAT) database (2008). Available at http://faostat.fao.org. Accessed on 4th December, 2011

  • Ganafa AA, Socci RR, Eatman D et al (2002) Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats. Am J Hypertens 15:725–731

    Article  CAS  PubMed  Google Scholar 

  • Gliemo MF, Calvin AM, Tamasib B et al (2008) Interactions between aspartame, glucose and xyliton in aqueous systems containing potassium sorbate. LWT Food Sci Technol 41:611–619

    Article  CAS  Google Scholar 

  • Gruenwald J, Herzberg F (2002) The global nutraceutical market. business briefing and innovative food ingredients, pp 28–31

  • Gunstone FD, Harwood JL, Padley F (1994) The lipid handbook, 2nd edn. Chapman and Hall, London, pp 128–157

    Google Scholar 

  • Hamid HA, Choo YM, Goh SH et al (1995) The ubiquinones of palm oil in nutrition. In: Ong AS, Niki HE, Packer L (eds) Lipids, health and disease. AOCS Press, Champaign, pp 122–128

    Google Scholar 

  • Han NM, May CY, Ngan MA et al (2006) Separation of coenzyme [Q10] from palm oil by supercritical fluid chromatography. Am J Appl Sci 3:1929–1932

    Article  CAS  Google Scholar 

  • Harborne JB, Baxter H, Moss GP (1999) Phytochemical dictionary: handbook of bioactive compounds from plants, 2nd edn. Taylor & Francis, London

    Google Scholar 

  • Hassan MA, Shirai Y (2003) Palm biomass utilization in Malaysia for the Production of bioplastic. In: Biomass-Asia-workshop. Available at www.biomassasiaworkshop.jp/presentation_files/21_Alihassan.pdf;2003

  • Hudiyono S, Septian A (2012) Optimization carotenoids isolation of the waste crude palm oil using α-amylase, β-amylase, and cellulose. IOSR J Appl Chem 2:7–12

    Google Scholar 

  • Ibrahim MNM, Nadiah MYN, Norliyana MS et al (2008) Separation of vanillin from oil palm empty fruit bunch lignin. Clean- Soil Air Water 36:287–291

    Article  CAS  Google Scholar 

  • Jung YH, Kim IJ, Kim JJ et al (2011) Ethanol production from oil palm trunks treated with aqueous ammonia and cellulase. Bioresour Technol 102:7307–7312

    Article  CAS  PubMed  Google Scholar 

  • Kamarun Zaman, H B (2008) Production of high fibre bread from oil palm pericarp fibre. Bachelor of Science (BSc) Thesis, Faculty of Applied Sciences, Universiti Teknologi MARA, Malaysia

  • Kato A, Yamaoka M, Gapor AB et al (2002) Tocopherols of oil palm leaflet. J Am Chem Soc, pp 60

  • Kausar H, Bhasin G, Zargar MA et al (2003) Palm oil alleviate 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion response in murine skin. Cancer Lett 192:151–160

    Article  CAS  PubMed  Google Scholar 

  • Kennedy M, Burstyn PG, Husbands DR (1978) Fat induced hypertension in rabbits: the effect of feeding diets containing high concentrations of safflower oil and palm oil. Proceed Nutr Soc 37:98A

    CAS  Google Scholar 

  • King A, Young G (1999) Characteristics and occurrence of phenolic phytochemicals. J Am Diet Assoc 99:213–218

    Article  CAS  PubMed  Google Scholar 

  • Lau HLN, Choo YM, Ma AN et al (2006) Quality of residual oil from palm-pressed mesocarp fiber (Elaeis guineensis) using supercritical CO2 with and without ethanol. J Am Oil Chem Soc 83:893–898

    Article  CAS  Google Scholar 

  • Lau HLN, Choo YM, Ma AN (2008) Selective extraction of palm carotene and vitamin E from fresh palm-pressed mesocarp fiber (Elaeis guineensis) using supercritical CO2. J Food Eng 84:289–296

    Article  CAS  Google Scholar 

  • Law KN, Jiang X (2001) Comparative paper making properties of oil palm empty fruit bunch. TAPPI 84:95

    CAS  Google Scholar 

  • Li F, Tan W, Kang Z et al (2010) Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. Atherosclerosis 211:278–282

    Article  CAS  PubMed  Google Scholar 

  • Majima T, Tsutsumi M, Nishino H (1998) Inhibitory effects of beta-carotene, palm carotene, and green tea polyphenols on pancreatic carcinogenesis initiated by N-nitorsobis (2-oxopropyl) amine in Syrian golden hamsters. Pancreas 16:13–18

    Article  CAS  PubMed  Google Scholar 

  • Marchione V (2011) An extract that could lower blood sugar naturally. In: Alternative Remedies, Blood Sugar, Diabetes, Food and Nutrition. The Doctors Health Press. Available at http://www.doctorshealthpress.com/diabetes-articles/an-extract-that-could-lower-blood-sugar-naturally. Accessed on 2nd December, 2011

  • Mard SA, Jalalvand K, Jafarinejad M et al (2010) Evaluation of the antidiabetic and antilipaemic activities of the hydroalcoholic extract of phoenix dactylifera palm leaves and its fractions in alloxan-induced diabetic rats. Malay J Med Sci 17:4–13

    Google Scholar 

  • Marini AM, Yatim AM, Babji AS et al (2006) Evaluation of nutrient contents and amino acid profiling of various types of palm kernel cake (PKC). J Sci Technol 2:135–141

    Google Scholar 

  • Miyazawa T, Rebhung F, Fujimoto K et al (1994) The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. J Nutr Sci Vitamol 40:315–324

    Article  Google Scholar 

  • Mohammad R, Sarmidi MR, Hesham A et al (2009) Oil palm: the rich mine for pharma, food, feed and fuel industries. Am-Eur J Agric Environ Sci 5:767–776

    CAS  Google Scholar 

  • Mustaffa B, Mizairi S, Hawari H (1991) Palm kernel cake in cattle feedlotting. Asean Food 6:102–103

    Google Scholar 

  • Mustapa AN, Manan ZA, Mohd Azizi CY et al (2011) Extraction of b-carotenes from palm oil mesocarp using sub-critical R134a. Food Chem 125:262–267

    Article  CAS  Google Scholar 

  • Nandi S, Gangopadhyay S, Ghosh S (2005) Production of medium chain glycerides from coconut and palm kernel fatty acid distillates by lipase-catalyzed reactions. Enzyme Microb Technol 36:725–728

    Article  CAS  Google Scholar 

  • Neo YP, Ariffin A, Tan CP et al (2008) Determination of oil palm fruits phenolic compounds and their antioxidants activities using spectrophotometric methods. Int J Food Sci Technol 43:1832–1837

    Article  CAS  Google Scholar 

  • Neo YP, Ariffin A, Tan CP (2010) Phenolic acid analysis and antioxidant activity assessment of oil palm (E. guineensis) fruit extract. Food Chem 122:353–359

    Article  CAS  Google Scholar 

  • Nesaretnam K, Doraisamy S, Darbre PD (2000) Effect of a carotene concentrate on the growth of human breast cancer cells and pS2 gene expression. Toxicol 151:117–126

    Article  CAS  Google Scholar 

  • Ng MH, Choo YM (2010) Determination of antioxidants in oil palm leaves (Elaeis guineensis). Am J Appl Sci 7:1243–1247

    Article  Google Scholar 

  • Ng H, Choo YM (2012) Determination of antioxidants in oil palm empty fruit bunches. Am J Appl Sci 9:1862–1867

    Google Scholar 

  • Ng MH, Choo YM, Ma AN, Chuah CH, Hashim MA (2006) Isolation and identification of individual palm carotenes using supercritical fluid chromatography. Malays J Sci 25:139–145

    Google Scholar 

  • Ng MH, Choo YM, Ma AN, Chuah CH, Hashim MA (2009) Determination of coenzyme Q9 and Q10 in developing palm fruits. J Am Oil Chem Soc 86:201–205

    Google Scholar 

  • Noeh BK, Thang YM, Zain MZM et al (2011) Palm pressed fibre oil: a new opportunity for premium hardstock. Int Food Res 18:769–773

    Google Scholar 

  • Norhidayah S, Baharin BS, Hamed M et al (2012) Squalene recovery from palm fatty acid distillate using supercritical fluid extraction. Int Food Res 19:1661–1667

    CAS  Google Scholar 

  • Ogbuagu MN (2008) The change in physico-chemical properties of blended oils of palm origin with soya bean oil. Glob J Pure Appl Sci 14:397–400

    CAS  Google Scholar 

  • Oluwafemi RA (2009) Palm kernel cake (PKC) utilization in monogastric animal feeding—implications for sustainable livestock development. Internet J Vet Med 6:1

    Google Scholar 

  • Oluwafemi RAI, Akpodiete OJ (2011) Comparison of the performance, haematology and serum chemistry of weaner pigs fed palm kernelcake with and without enzyme supplementation. Electron J Env Agric Food Chem 10:2940–2944

    Google Scholar 

  • O-Thong S, Boe K, Angelidaki I (2012) Thermophilic anaerobic co-digestion of oil palm empty fruit bunches with palm oil mill effluent for efficient biogas production. Appl Energy 93:648–654

    Article  CAS  Google Scholar 

  • Pacheco de Delahaye E, Cedres M, Alvarado A et al (1994) Substitution of wheat flour by defatted palm meal flour, rich source of dietetic fiber in the preparation of cookies and breads. Arch Latinoam Nutr 44:122–128

    CAS  PubMed  Google Scholar 

  • Perez JF, Gernat AG, Murillo JG (2000) The effect of different levels of palm kernel meal in layer diets. Poult Sci 79:77–79

    Google Scholar 

  • Posada LRJ, Kakuda SY, Xue SJ (2007) Extraction of tocotrienols from palm fatty acid distillates using molecular distillation. Sep Purif Technol 52:220–229

    Article  CAS  Google Scholar 

  • Pourmorad F, Hosseinimehr SJ, Shahabimajd N (2006) Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afric J Biotechnol 5:1142–1145

    CAS  Google Scholar 

  • Price KR, Johnson IT, Fenwick GR (1987) The chemistry and biological significance of saponins in foods and feedingstuffs. Crit Rev Food Sci Nutr 26:127–135

    Article  Google Scholar 

  • Puah CW, Choo YM, Ma AN et al (2006) Production of carotenoids-rich palm olein by supercritical fluid extraction. Malay J Sci 25:147–152

    Google Scholar 

  • Puah CW, Choo YM, Ma AN et al (2007) The effect of physical refining on palm vitamin E (Tocopherol, Tocotrienol and Tocomonoenol). Am J Appl Sci 4:374–377

    Article  CAS  Google Scholar 

  • Radhika MS, Bhaskaram P, Balakrishna N et al (2003) Red palm oil supplementation: a feasible diet-based approach to improve the vitamin A status of pregnant women and their infants. Food Nutr Bull 24:208–217

    CAS  PubMed  Google Scholar 

  • Rahman SHA, Choudhury JP, Ahmad AL (2004) Biotechnological production of xylitol from oil palm empty fruit bunch, a lignocellulosic waste. In: Proceedings of the 4th annual seminar of national science fellowship, 20–21 December 2004, Universiti Sains Malaysia, Pulau Pinang, Malaysia

  • Rakamthong C, Prasertsan P (2011) Decolorization and phenol removal of anaerobic palm oil mill effluent by Phanerochaete chrysosporium ATCC 24725. In: TIChE International Conference 2011. November 10–11, 2011, Hatyai, Songkhla, Thailand

  • Rosalina Tan RT, Mohamed S, Samaneh GF et al (2011) Polyphenol rich oil palm leaves extract reduce hyperglycaemia and lipid oxidation in STD-rats. Int Food Res 18:179–188

    CAS  Google Scholar 

  • Sambanthamurthi R (2011a) Oil palm vegetation liquor: a new source of phenolic bioactives. Br J Nutr 106:1655–1663

    Article  CAS  PubMed  Google Scholar 

  • Sambanthamurthi R (2011b) Positive outcomes of oil palm phenolics on degenerative diseases in animal models. Br J Nutr 106:1664–1675

    Article  CAS  PubMed  Google Scholar 

  • Sanagi MM, See HH, Ibrahim WAW, Naim AA (2005) Determination of carotene, tocopherols and tocotrienols in residue oil from palm pressed fiber using pressurized liquid extraction-normal phase liquid chromatography. Analyt Chimica Acta 538:71–76

    Article  CAS  Google Scholar 

  • Sandhya C, Sumantha A, Szakacs G (2005) Comparative evaluation of neutral protease production by Aspergillus oryzae in submerged and solid-state fermentation. Proc Biochem 40:2689–2694

    Article  CAS  Google Scholar 

  • Sarunya C, Nipon T, Duang B et al (2006) Stanol synthesis from palm oil distillate. Chiang Mai J Sci 33:109–116

    Google Scholar 

  • Sasidharan S, Nilawatyi R, Xavier R et al (2010) Wound healing potential of Elaeis guineensis Jacq. leaves in an infected albino rat model. Molecul 15:3186–3199

    Article  CAS  Google Scholar 

  • Sasidharan S, Logeswaran S, Latha LY (2012) Wound healing activity of Elaeis guineensis leaf extract ointment. Int J Molecul Sci 13:336–347

    Article  CAS  Google Scholar 

  • Schmidt J H (2007) Life assessment of rapeseed oil and palm oil. Ph.D. Thesis, Part 3: Lifecycle inventory of rapeseed oil and palm oil. Department of Development and Planning, Aalborg University, Aalborg

  • Schofield P, Mbugua DM, Pell AN (2001) Analysis of condensed tannins: a review. Anim Feed Sci Technol 91:21–40

    Article  CAS  Google Scholar 

  • Schunemann HJ, McCann S, Grant BJB, Trevisan M et al (2002) Lung function in relation to intake of carotenoids and other antioxidant vitamins in a population-based study. Am J Epidemil 155:463–471

    Article  Google Scholar 

  • Scortichini M, Pia Rossi M (1991) Preliminary in vitro evaluation of the antimicroabial activity of triterpenes and terpenoids towards Erwinia amylovora (Burril). J Bacteriol 71:109–112

    Article  CAS  Google Scholar 

  • Seyyed AM, Kowthar J, Masoumeh J et al (2010) Evaluation of the antidiabetic and Antilipaemic Activities of the Hydroalcoholic Extract of Phoenix Dactylifera Palm Leaves and its Fractions in Alloxan-Induced Diabetic Rats. Malay J Med Sci 17:4–13

    Google Scholar 

  • Shamala DS, Soon-Sen L, Najwa A (2010) Effects of oil palm phenolics on tumor cells in vitro and in vivo. Afric J Food Sci 4:495–502

    Google Scholar 

  • Sies H, Stahl W (2004) Nutritional protection against skin damage from sunlight. Annu Rev Nutr 24:173–200

    Article  CAS  PubMed  Google Scholar 

  • Siew WL (1990) Palm oil sterols. Palm Oil Dev 18:23–24

    Google Scholar 

  • Starks MA, Starks SL, Kingsley M et al (2008) The effects of phosphatidylserine on endocrine response to moderate intensity exercise. J Int Soc Sport Nutr 5:11

    Article  CAS  Google Scholar 

  • Sundram K, Sambanthamurthi R, Tan YA (2003) Palm fruit chemistry and nutrition. Asia Pac J Clin Nutr 12:355–362

    CAS  PubMed  Google Scholar 

  • Syahmi ARM, Vijayarathna S, Sasidharan S (2010) Acute oral toxicity and brine shrimp lethality of Elaeis guineensis Jacq., (oil palm leaf) methanol extract. Molecul 15:8111–8121

    Article  CAS  Google Scholar 

  • Tay YP, Choo YM (2000) Valuable minor constituents of commercial red palm olein: carotenoids, vitamin E, ubiquinones and sterols. J Oil Palm Res 12:14–24

    Article  Google Scholar 

  • Ukoh GC, Ayinde BA, Usifoh CO et al (2004) Comparative Antibacterial activities of Oil palm Elaeis guinneesis Jacq. (Palmae) nut and Coconut Cocos nucifera L. (Palmae) Shells pyrolysates. Ife J Sci 6:91–94

    Google Scholar 

  • Umegaki K, Uramoto H, Suzuki J et al (1997) Feeding mice with palm carotene prevents DNA damage in bone marrow and reduction of peripheral leukocyte counts, and enhances survival following X-ray irradiation. Carcinogenesis 18:1943–1947

    Article  CAS  PubMed  Google Scholar 

  • Van den Berg H (1999) Carotenoid interactions. Nutr Rev 57:1–10

    Article  PubMed  Google Scholar 

  • Van Stuijvenberg ME, Dhansay MA, Lombard CJ et al (2001) The effect of a biscuit with red palm oil as a source of beta-carotene on the vitamin A status of primary school children: a comparison with beta-carotene from a synthetic source in a randomised controlled trial. Eur J Clin Nutr 55:657–662

    Article  PubMed  CAS  Google Scholar 

  • Verma DD, Hartner WC, Thakkar V (2007) Protective effect of coenzyme Q10-loaded liposomes on the myocardium in rabbits with an acute experimental myocardial infarction. Pharm Res 24:2131–2137

    Article  CAS  PubMed  Google Scholar 

  • Wahid MB, Abdullah SNA, Henson IE (2005) Oil palm-achievements and potential. Plant Prod Sci 8:288–297

    Article  Google Scholar 

  • Wan Zahari M, Sato J, Furuich S et al (2004). Recent development on the processing and utilization of complete feed based on oil palm fronds for ruminant feeding in Malaysia. In: Tanaka R, Cheng LH (ed), In: Proceedings of the 3rd USM-JIRCAS Joint International Symposium. JIRCAS Working Report No. 39, Penang, Malaysia, pp 24–27

  • Yap SC, Choo YM, Ooi CK, Ong ASH, Goh SH (1991) Quantitative analysis of carotenes in the oil from different palm species. Elaeis 3:309–378

    Google Scholar 

  • Yu FL, Gapor A, Bender W (2005) Studies on the preventive effect of red palm oil on 17-beta-estradiol epoxidation and the potential against breast cancer carcinogenesis at the initiation. In: Proceedings of PIPOC 2005, pp 192–201

  • Yu FL, Gapor MT, Bender W et al (2008) Palm oil tocotrienols as antioxidants and chemopreventive agents. J Oil Palm Res 20:91–101

    Article  Google Scholar 

  • Yun PN, Ariffin A, Tan CP (2008) Determination of oil palm fruit phenolic compounds and their antioxidant activities using spectrophotometric methods. Int J Food Sci Technol 43:1832–1837

    Article  CAS  Google Scholar 

  • Yusoff S (2006) Renewable energy from palm oil-innovation on effective utilization of waste. J Clean Prod 14:87–93

    Article  Google Scholar 

  • Zadák Z, Hyspler R, Tichá A (2006) Polyunsaturated fatty acids, phytosterols and cholesterol metabolism in the Mediterranean diet. Acta Medica 49:23–26

    PubMed  Google Scholar 

  • Zadak Z, Hyspler R, Ticha A, Solichova D, Blaha V, Melichar B (2006) Poly-unsatruated fatty acids, phytosterols and cholesterol metabolism in the Mediterranean diet. Acta Medica 49:23–26

    Google Scholar 

  • Zeb A, Mehmood S (2004) Carotenoids contents from various sources and their potential health applications. Pakistan J Nutr 3:199–204

    Article  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Universiti Sains Malaysia (Research University Grant No. 854002 and USM Fellowship) for the financial support given.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Cynthia Ofori-Boateng.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ofori-Boateng, C., Lee, K.T. Sustainable utilization of oil palm wastes for bioactive phytochemicals for the benefit of the oil palm and nutraceutical industries. Phytochem Rev 12, 173–190 (2013). https://doi.org/10.1007/s11101-013-9270-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11101-013-9270-z

Keywords

Navigation