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Advances in non-surgical treatments for urinary tract infections in children

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World Journal of Urology Aims and scope Submit manuscript

Abstract

Objective

With growing antibiotics failure due to emerging resistance of bacteria, non-surgical management of pediatric UTI plays a more important role because of its non-invasive characteristics and little adverse effects.

Methods

We searched the Pubmed for management of UTI in children other than surgical correction and antibiotics using terms: risk factor, prepuce/phimosis, steroid cream/steroid, behavioral therapy, urotherapy, biofeedback/pelvic floor exercise, adrenergic antagonist, anticholinergics, diet/dietary, dysfunctional voiding/dysfunctional elimination syndrome, constipation, dietary, clean intermittent catheterization, probiotics/lactobacillus, cranberry, vitamin supplement, breastfeeding, breast milk, with infant/child/children/pediatrics/pediatrics and urinary tract infection.

Results

The proposed non-surgical management of pediatric UTI included behavioral modification (timed voiding and adequate fluids intake), topical steroid for phimosis, nutrient supplements (breast milk, cranberry, probiotics, and vitamin A), biofeedback training for dysfunctional voiding, anticholinergics for reducing intravesical pressure, alpha-blockers in dysfunctional voiding and neurogenic bladder, and intermittent catheterization for children with large PVR.

Conclusion

The published reports usually included small number of patients and were lacking of randomization and controlled group. Further well-designed studies are warranted to support the concepts of non-operative management for pediatric UTI.

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Conflict of interest

All the authors had nothing to disclose and no conflict of interest.

Author information

Authors and Affiliations

  1. Division of Urology, Buddhist Tzu Chi General Hospital, Taipei Branch, No. 289 Chienkuo Road, Xindian City, Taipei, 231, Taiwan

    Stephen Shei-Dei Yang, Chia-Da Lin & Shang-Jen Chang

  2. Department of Urology, Medical College of Buddhist Tzu Chi University, Hualien, Taiwan

    Stephen Shei-Dei Yang, Chia-Da Lin & Shang-Jen Chang

  3. Division of Urology, Department of Surgery Keelung Hospital, Keelung, Taiwan

    I-Ni Chiang

  4. Department of Urology, National Taiwan University Hospital, Taipei, Taiwan

    I-Ni Chiang

Authors
  1. Stephen Shei-Dei Yang
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  2. I-Ni Chiang
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  3. Chia-Da Lin
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  4. Shang-Jen Chang
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Corresponding author

Correspondence to Shang-Jen Chang.

Additional information

This manuscript was published originally in: Naber KG, Schaeffer AJ, Heyns CF, Matsumoto T, Shoskes DA, Bjerklund Johansen TE (eds): Urogenital Infections. European Association of Urology—International Consultation on Urological Diseases, 1st edition 2010, Arnhem, The Netherlands, ISBN:978-90-79754-41-0.

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Yang, S.SD., Chiang, IN., Lin, CD. et al. Advances in non-surgical treatments for urinary tract infections in children. World J Urol 30, 69–75 (2012). https://doi.org/10.1007/s00345-011-0700-5

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  • DOI: https://doi.org/10.1007/s00345-011-0700-5

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