Abstract
Mercury (Hg) contamination in environmental matrices and associated human exposure has been recognized as a critical long-lasting issue worldwide. However, studies are still elusive that summarized the overall status of Hg pollution and its impacts on public health in Pakistan. Hence, this review encompasses the environmental prevalence, potential sources, and human exposure tendencies to Hg contamination in Pakistan. Reviewed literature revealed jolting levels of Hg in various environmental samples, such as dust, soil, water, and air collected from the residential and industrial areas. Inhalation of Hg via dust particle was identified as the primary pathway for human exposure, while atmospheric deposition and gold mining are identified as the two primary sources of Hg contamination in the environment. Considering human exposure, the highest bioaccumulation of Hg was ranged from 5885 to 8698 µg/kg in hair samples collected from the residents of the Kashmir Valley, Pakistan. However, in the lower Himalayan regions, including Islamabad and Swabi, the concentration of Hg in hair samples was reported at 1085 µg/kg, slightly beyond WHO devised reference dose (RfD) of Hg (1000 µg/kg). This review revealed the worst scenario of Hg contamination in human biomatrices and environmental compartments in Pakistan, which needed immediate rehabilitation measures.
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References
Andreoli V, Sprovieri F (2017) Genetic aspects of susceptibility to mercury toxicity: an overview. Int J Environ Res Public Health 14:93
Ashraf M, Tariq J, Jaffar M (1991) Contents of trace metals in fish, sediment and water from three freshwater reservoirs on the Indus River, Pakistan. Fish Res 12:355–364
Azizullah A, Khattak MNK, Richter P, Häder D-P (2011) Water pollution in Pakistan and its impact on public health—a review. Environ Int 37:479–497
Bárány E, Bergdahl IA, Bratteby L-E, Lundh T, Samuelson G, Schütz A, Skerfving S, Oskarsson A (2002) Trace element levels in whole blood and serum from Swedish adolescents. Sci Total Environ 286:129–141
Basu N, Horvat M, Evers DC, Zastenskaya I, Weihe P, Tempowski J (2018) A state-of-the-science review of mercury biomarkers in human populations worldwide between 2000 and 2018. Environ Health Perspect 126:106001
Bhowmik A, Schafer R, Alamdar A, Katsoyiannis I, Ali M, Ali N, Bokhari H, Eqani S (2015) Predictive risk mapping of drinking water resources in the Indus delta floodplains: exposure estimation of arsenic and other trace metals pose serious health risks to population. Sci Total Environ 538:306–316
Biber K, Khan SD, Shah MT (2015) The source and fate of sediment and mercury in Hunza River basin, Northern Areas, Pakistan. Hydrol Process 29:579–587
Björnberg KA, Vahter M, Grawé KP, Berglund M (2005) Methyl mercury exposure in Swedish women with high fish consumption. Sci Total Environ 341:45–52
Boncompagni E, Muhammad A, Jabeen R, Orvini E, Gandini C, Sanpera C, Ruiz X, Fasola M (2003) Egrets as monitors of trace-metal contamination in wetlands of Pakistan. Arch Environ Contam Toxicol 45:399–406
Burmistrz P, Kogut K, Marczak M, Zwoździak J (2016) Lignites and subbituminous coals combustion in Polish power plants as a source of anthropogenic mercury emission. Fuel Process Technol 152:250–258
Castaño A, Cutanda F, Esteban M, Pärt P, Navarro C, Gómez S, Rosado M, López A, López E, Exley K (2015) Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries. Environ Res 141:58–68
Cole DC, Kearney J, Sanin LH, Leblanc A, Weber J-P (2004) Blood mercury levels among Ontario anglers and sport-fish eaters. Environ Res 95:305–314
Dong X, Li C, Li J, Wang J, Liu S, Ye B (2010) A novel approach for soil contamination assessment from heavy metal pollution: a linkage between discharge and adsorption. J Hazard Mater 175:1022–1030
Driscoll CT, Mason RP, Chan HM, Jacob DJ, Pirrone N (2013) Mercury as a global pollutant: sources, pathways, and effects. Environ Sci Technol 47:4967–4983
Eqani SAMAS, Bhowmik AK, Qamar S, Shah STA, Sohail M, Mulla SI, Fasola M, Shen H (2016a) Mercury contamination in deposited dust and its bioaccumulation patterns throughout Pakistan. Sci Total Environ 569:585–593
Eqani SAMAS, Kanwal A, Bhowmik AK, Sohail M, Ullah R, Ali SM, Alamdar A, Ali N, Fasola M, Shen H (2016b) Spatial distribution of dust–bound trace elements in Pakistan and their implications for human exposure. Environ Pollut 213:213–222
Farooq MA, Yasmin N, Mughal S (2010) Human induced impact on Malir River Basin Karachi, Pakistan. World Appl Sci J 9:1450–1456
Giang A, Stokes LC, Streets DG, Corbitt ES, Selin NE (2015) Impacts of the minamata convention on mercury emissions and global deposition from coal-fired power generation in Asia. Environ Sci Technol 49:5326–5335
Hightower J, Moore D (2003) Mercury levels in high-end consumers of fish. Environ Health Perspect 111:604–608
Ip P, Wong V, Ho M, Lee J, Wong W (2004a) Environmental mercury exposure in children: South China’s experience. Pediatr Int 46:715–721
Ip P, Wong V, Ho M, Lee J, Wong W (2004b) Mercury exposure in children with autistic spectrum disorder: case–control study. J Child Neurol 19:431–434
Jamil N, Baqar M, Shaikh IA (2015) Assessment of contamination in water and soil surrounding a chlor-alkali plant: a case study. J Chem Soc Pak 37:173–178
Johnsson C, Schütz A, Sällsten G (2005) Impact of consumption of freshwater fish on mercury levels in hair, blood, urine, and alveolar air. J Toxicol Environ Health A 68:129–140
Khan MN, Wasim AA, Sarwar A, Rasheed MF (2011) Assessment of heavy metal toxicants in the roadside soil along the N-5, National Highway, Pakistan. Environ Monit Assess 182:587–595
Khan S, Shah MT, Din IU, Rehman S (2012) Mercury exposure of workers and health problems related with small-scale gold panning and extraction. J Chem Soc Pak 34:870–876
Lech T, Sadlik JK (2004) Total mercury levels in human autopsy materials from a nonexposed Polish population. Arch Environ Health 59:50–54
Lindberg A, Björnberg KA, Vahter M, Berglund M (2004) Exposure to methylmercury in non-fish-eating people in Sweden. Environ Res 96:28–33
Ozaki H, Watanabe I, Kuno K (2004) As, Sb and Hg distribution and pollution sources in the roadside soil and dust around Kamikochi, Chubu Sangaku National Park, Japan. Geochem J 38:473–484
Qureshi MA, Mastoi GM, Laghari ZA, Lashari KH, Panhwar F, Palh ZA (2015) Heavy metal pollution investigation of left bank outfall drain of coastal district Badin, Sindh, Pakistan by Using Arc GIS. Int J Environ Monit Anal 3:122–132
Rahman A (1996) Groundwater as source of contamination for water supply in rapidly growing megacities of Asia: case of Karachi, Pakistan. Water Sci Technol 34:285–292
Riaz A, Khan S, Shah MT, Li G, Gul N, Shamshad I (2016) Mercury contamination in the blood, urine, hair and nails of the gold washers and its human health risk during extraction of placer gold along Gilgit, Hunza and Indus rivers in Gilgit-Baltistan, Pakistan. Environ Technol Innov 5:22–29
Rice DC (2004) The US EPA reference dose for methylmercury: sources of uncertainty. Environ Res 95:406–413
Schober SE, Sinks TH, Jones RL, Bolger PM, McDowell M, Osterloh J, Garrett ES, Canady RA, Dillon CF, Sun Y (2003) Blood mercury levels in US children and women of childbearing age, 1999–2000. JAMA 289:1667–1674
Seigneur C, Vijayaraghavan K, Lohman K, Karamchandani P, Scott C (2004) Global source attribution for mercury deposition in the United States. Environ Sci Technol 38:555–569
Selin NE (2009) Global biogeochemical cycling of mercury: a review. Ann Rev Environ Res 34:43–63
Sundseth K, Pacyna JM, Pacyna EG, Pirrone N, Thorne RJ (2017) Global sources and pathways of mercury in the context of human health. Int J Environ Res Public Health 14:105
Tariq J, Jaffar M, Ashraf M (1994) Trace metal concentration, distribution and correlation in water, sediment and fish from the Ravi River, Pakistan. Fish Res 19:131–139
Weihe P, Grandjean P, Jørgensen PJ (2005) Application of hair-mercury analysis to determine the impact of a seafood advisory. Environ Res 97:201–208
Xu X, Nie S, Ding H, Hou FF (2018) Environmental pollution and kidney diseases. Nat Rev Nephrol 14:313–324
Zhang L, Wong M (2007) Environmental mercury contamination in China: sources and impacts. Environ Int 33:108–121
Zhang X, Wang H, He L, Lu K, Sarmah A, Li J, Bolan NS, Pei J, Huang H (2013) Using biochar for remediation of soils contaminated with heavy metals and organic pollutants. Environ Sci Pollut Res 20:8472–8483
Zhu S, Zhang Z, Žagar D (2018) Mercury transport and fate models in aquatic systems: a review and synthesis. Sci Total Environ 639:538–549
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The current work is supported by the National Key R&D Program of China (No. 2017YFD0800302) and the Natural Science Foundation of China (4157312).
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Ali, W., Junaid, M., Aslam, M.W. et al. A Review on the Status of Mercury Pollution in Pakistan: Sources and Impacts. Arch Environ Contam Toxicol 76, 519–527 (2019). https://doi.org/10.1007/s00244-019-00613-0
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DOI: https://doi.org/10.1007/s00244-019-00613-0