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Maintenance of a lymphocytic choriomeningitis-free mouse unit in Kenya

Entretien d'un élevage de souris indemne de chorioméningite lymphocytaire au Kenya

Mantenimiento de una unidad de ratones libres de coriomeningitis linfocitica en Kenya

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Summary

The maintenance of an LCM-free colony of mice in Kenya is described. Attention is drawn to the dangers of reinfection by wild rodents and, possibly, other means. Details are given of the measures instigated to control rodents and other pests, to sterilise or disinfect incoming food, bedding and equipment and the training of staff in hygienic techniques. The problems encountered in maintaining such a colony in a developing country are outlined.

Résumé

Cet article décrit l'entretien au Kenya d'un élevage de souris indemne de chorioméningite lymphocytaire. On attire l'attention sur les dangers de réinfection que constituent les rongeurs sauvages et, éventuellement, d'autres vecteurs. Des détails sont fournis à propos des mesures mises en oeuvre pour lutter contre les rongeurs et les autres parasites, pour stériliser ou désinfecter les aliments, les cages et le matériel, enfin pour entraîner le personnel aux méthodes d'hygiène. Les problèmes rencontrés pour l'entretien d'un tel élevage dans un pays en voie de déve oppement sont soulignés.

Sumario

El mantenimiento de una colonia de ratones, libre de LCM en Kenya es descrito. Se hace hincapié sobre los peligros de reinfección por roedores silvestres y por otros medios. Se dan detalles de las medidas urgidas para controlar roedores y otras pestes, para esterilizar y desinfectar alimentos, cama y equipo y para entrenar al personal en tecnicas higiénicas. Se hace un bosquejo de los problemas encontrados en mantener tal colonia en un pais en desarrollo.

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References

  • Andrewes, C. &Pereira, H. G. (1967).Viruses of Vertebrates 2nd Edition. Bailliere, Tindall & Cassell, London. pp. 149–152.

    Google Scholar 

  • Armstrong, C. (1955) inT. G. Hull Diseases Transmitted from Animals to Man. 4th Edition, Charles Thomas & Co. Springfield. p. 633.

    Google Scholar 

  • Armstrong, C. &Sweet, L. K. (1939). Lymphocytic choriomeningitis: report of two cases with recovery of the virus from gray mice (Mus musculus) trapped in the two infected households. Public Health Reports Washington54, 673–684.

    Google Scholar 

  • Armstrong, C., Wallace, J. J. &Ross, L. (1940). Lymphocytic choriomeningitis. gray miceMus musculus, a reservoir for the infection. Public Health Reports Washington55, 1222.

    Google Scholar 

  • Cooper, J. E. (1973). Establishment of a mouse colony free of lymphocytic choriomeningitis in Kenya.Laboratory Animals (in press).

  • Cunningham-Van Someren, G. R. (1952). Tests with ‘Gammexane’ larvicide (benzene hexachloride) as a rodenticide.East African Medical Journal,29, 107–119.

    Google Scholar 

  • Hoyland, F., Knight, E. H. &Skinner, H. H. (1972). Eradication of lymphocytic choriomeningitis (LCM) virus—a human pathogen—from a mouse breeding colony.Journal of the Institute of Animal Technicians,23, 6–18.

    Google Scholar 

  • Lehmann-Grube, F. (1971).Lymphocytic Choriomeningitis Virus. Springer-Verlag, New York.

    Google Scholar 

  • Maurer, F. D. (1964). Lymphocytic choriomeningitis.Laboratory Animal Care,14, 415–419.

    Google Scholar 

  • Milzer, A. (1942). Studies on the transmission of lymphocytic choriomeningitis virus by arthropods.Journal of Infectious Diseases,70, 152–172.

    Google Scholar 

  • Mims, C. A. (1970). Observations on mice infected congenitally or neonatally with lymphocytic choriomeningitis (LCM) virus.Archiv fur die gesamte Virusforschung,30, 67–74.

    Google Scholar 

  • Seamer, J. (1965). The growth, reproduction and mortality of mice made immunologically tolerant to lymphocytic choriomeningitis virus by congenital infection.Archiv fur die gasamte Virusforschung,15, 169–177.

    Google Scholar 

  • Skinner, H. H. &Knight, E. H. (1969). Studies on murine lymphocytic choriomeningitis within a partially infected colony.Laboratory Animals,3, 175–184.

    Google Scholar 

  • Skinner, H. H. &Knight, E. H. (1971). Monitoring mouse stocks for lymphocytic choriomeningitis virus a human pathogen.Laboratory Animals,5, 73–87.

    Google Scholar 

  • Swynnerton, G. H. &Hayman, R. W. (1950). A checklist of the land mammals of the Tanganyika Territory and the Zanzibar Protectorate.Journal of the East African Natural History Society,XX, 274–392.

    Google Scholar 

  • Tobin, J. O'H. (1968). Viruses transmissible from laboratory animals to man.Laboratory Animals,2, 19–28.

    Google Scholar 

  • Traub, E. (1941). Uber den Einfluss der latenten Choriomeningitis infektion auf die Entstehung der lymphomatose bei Weissen.Zentralblatt fur Bakteriologie Abteilung originale 147, 16–25.

    Google Scholar 

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Authors and Affiliations

  1. Veterinary Research Laboratory, P.O. Kabete, Kenya

    J. E. Cooper

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  1. J. E. Cooper
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On F.C.O./O.D.A. Secondment from the Institute for Research on Animal Diseases, Compton England.

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Cooper, J.E. Maintenance of a lymphocytic choriomeningitis-free mouse unit in Kenya. Trop Anim Health Prod 5, 174–180 (1973). https://doi.org/10.1007/BF02251386

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  • DOI: https://doi.org/10.1007/BF02251386

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