Abstract
Chlordane residues were determined in human milk samples. Quantitative analysis was conducted for six residual compounds in the milk of 29 healthy Japanese donors who had experienced no occupational exposure to chlordane. All six compounds were detected in the milk from each donor. Geometric mean levels in whole milk (ng/ mL) and milk fat (ng/g), respectively, were:trans-nonachlor 0.55, 15.7; oxychlordane 0.39, 11.5;cis-nonachlor 0.14, 4.00;cis-chlordane 0.09, 3.08;trans-chlordane 0.04, 1.20; heptachlor epoxide 0.66, 20.0.
In terms of the concentration (in both the whole milk and fat), a significant positive correlation was noted between any two compounds oftrans-nonachlor,cis-nonachlor, and oxychlordane. The residue level of each of these compounds had a significant positive correlation with the lipid content of the milk.
The level of chlordane residues in human milk was not very high, but the data suggest widespread chlordane contamination among the general Japanese population.
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Tojo, Y., Wariishi, M., Suzuki, Y. et al. Quantitation of chlordane residues in mothers' milk. Arch. Environ. Contam. Toxicol. 15, 327–332 (1986). https://doi.org/10.1007/BF01066398
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DOI: https://doi.org/10.1007/BF01066398