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Disinfection: A Trade-Off Between Microbial and Chemical Risks

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A New Paradigm for Environmental Chemistry and Toxicology

Abstract

While the disinfection of drinking water has largely eliminated the threat of waterborne diseases, it has resulted in an unintended consequence; the byproducts produced as a result of the disinfection process (DBPs). Every aspect of the water treatment process from source water acquisition to treated water distribution has an impact on this trade-off between microbial and chemical risk. Water utilities must consider how these variables interact within a complex system. Optimization of water treatment to balance microbial and chemical risks requires expertise from analytical chemists, toxicologists, engineers, and epidemiologists to characterize the classes of DBPs that are driving the toxicity associated with disinfected water beyond currently regulated DBPs. This chapter discusses how decisions made from source to tap affect water quality and the formation of DBPs using case studies from around the world.

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References

  • Agus E, Sedlak DL (2010) Water Res 44(5):1616–1626

    Article  CAS  Google Scholar 

  • Allen JM, Cuthbertson AA, Liberatore HK, Kimura SY, Mantha A, Edwards MA, Richardson SD (2017) J Environ Sci 58:271–284

    Article  Google Scholar 

  • Alpatova AL, Baumann MJ, Davies SH, Masten SJ (2013) Environ Chem Lett 11(3):309–313

    Article  CAS  Google Scholar 

  • Bellar TA, Lichtenberg JJ, Kroner RC (1974) C J Am Water Work Assoc 66(12):703–706

    Article  CAS  Google Scholar 

  • Bellona C, Drewes EJ (2005) Memb Sci 249:227–234

    Article  CAS  Google Scholar 

  • Bellona C, Heil D, Yu C, Fu P, Drewes JE (2012) Sep Purif Technol 85:69–76

    Article  CAS  Google Scholar 

  • Bennett A (2013) Filtr Sep 50(3):32–39

    Article  Google Scholar 

  • Beranek DT, Weis CC, Evans FE, Chetsanga CJ, Kadlubar FF (1983) Biochem Biophys Res Commun 110(2):625–631

    Article  CAS  Google Scholar 

  • Bolto B, Gregory J (2007) Water Res 41(11):2301–2324

    Article  CAS  Google Scholar 

  • Bond T, Henriet O, Goslan EH (2009) Environ Sci Technol 43(15):5982–5989

    Google Scholar 

  • Bond T, Huang J, Templeton MR, Graham N (2011) Water Res 45(15):4341–4354

    Article  CAS  Google Scholar 

  • Bond T, Templeton MR, Graham N (2012) J Hazard Mater 235–236:1–16

    Article  CAS  Google Scholar 

  • Boorman GA, Dellarco V, Dunnick JK, Chapin RE, Hauchman F, Gardner H, Cox M, Sills RC, Boorman GA, Dellarco V, Dunnick JK, Chapin RE, Hunter S, Hauchman F, Gardner H, Cox M, Sills RC (1999) Environ Heal Perspect 107:207–217

    CAS  Google Scholar 

  • Brown MR, Garland CD, Jeffrey SW, Jameson ID, Leroi JM (1993) J Appl Phycol 5(3):285–296

    Article  CAS  Google Scholar 

  • Bull RJ, Reckhow DA, Li X, Humpage AR, Joll C, Hrudey SE (2011) Toxicology 286(1–3):1–19

    Article  CAS  Google Scholar 

  • Canada Health (2017) Guidelines for Canadian drinking water quality—Summary table. Ontario, Ottawa

    Google Scholar 

  • Cantor AF (2006) Am Water Work Assoc 98(1):117–126

    Google Scholar 

  • Carpinteiro I, Rodil R, Quintana JB, Cela R (2017) Water Res 120:280–289

    Article  CAS  Google Scholar 

  • Centers for Disease Control and Prevention (2019) History of drinking water treatment: a century of U.S. water chlorination and treatment: one of the ten greatest public health achievements of the 20th century. https://www.cdc.gov/healthywater/drinking/history.html. Accessed Mar 19, 2019

  • Chen X, Stewart PS (1996) Environ Sci Technol 30(6):2078–2083

    Article  CAS  Google Scholar 

  • Chen B, Westerhoff P (2010) Water Res 44(13):3755–3762

    Article  CAS  Google Scholar 

  • Chen Y, Qin B, Teubner K, Dokulil MT (2003) J Plankton Res 25(4):445–453

    Article  Google Scholar 

  • Chiu CA, Westerhoff P, Ghosh A (2012) J Am Water Works Assoc 104(7)

    Google Scholar 

  • Chu W, Gao N, Deng Y, Templeton MR, Yin D (2011) Bioresour Technol 102(24):11161–11166

    Article  CAS  Google Scholar 

  • Chu W, Li C, Gao N, Templeton MR, Zhang Y (2015) Chemosphere 121:33–38

    Article  CAS  Google Scholar 

  • Chu W, Yao D, Deng Y, Sui M, Gao N (2017) J Hazard Mater 327:153–160

    Article  CAS  Google Scholar 

  • Croft HD, Walling D, Ambrose G (2015) City of Flint: water system questions & answers. Flint, MI

    Google Scholar 

  • Cuthbertson AA, Kimura SY, Liberatore HK, Summers RS, Knappe DRU, Stanford BD, Maness JC, Mulhern RE, Selbes M, Richardson SD (2019) Environ Sci Technol 53:5987–5999

    Article  CAS  Google Scholar 

  • Del Toral MA (2015) High lead levels in flint. Michigan—Interim report, Chicago, Il

    Google Scholar 

  • Deng J, Qin B, Paerl HW, Zhang Y, Ma J, Chen Y (2014) Freshw Biol 59:1076–1085

    Article  Google Scholar 

  • Ding S, Deng Y, Bond T, Fang C, Cao Z, Chu W (2019) Water Res

    Google Scholar 

  • Dotson A, Westerhoff P (2019) Am Water Work Assoc 101(9):101–115

    Article  Google Scholar 

  • Dotson AD, Rodriguez CE, Linden KG (2012) J Am Water Work Assoc 104(5):318–324

    Article  CAS  Google Scholar 

  • Drewes JE, Bellona C, Oedekoven M, Xu P, Kim TU, Amy G (2005) Environ Prog 24(4):400–409

    Article  CAS  Google Scholar 

  • Duan H, Ma R, Xu X, Kong F, Zhang S, Kong W, Hao J, Shang L (2009) Environ Sci Technol 43(10):3522–3528

    Article  CAS  Google Scholar 

  • European Union (1998) Council directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption

    Google Scholar 

  • Fang J, Ma J, Yang X, Shang C (2010a) Water Res 44(6):1934–1940

    Article  CAS  Google Scholar 

  • Fang J, Yang X, Ma J, Shang C, Zhao Q (2010b) Water Res 44(20):5897–5906

    Article  CAS  Google Scholar 

  • Federal Register (1998) 40 CFR parts 9, 141, 142. 63(241):69390–69476

    Google Scholar 

  • Fu KZ, Moe B, Li XF, Le XC (2015) J Environ Sci (China) 32:249–251

    Google Scholar 

  • Gao Y, Pang S, Jiang J, Zhou Y, Li J, Wang L-H, Lu X-T, Yuan L-P (2016) Environ Sci Technol 50:9608–9618

    Article  CAS  Google Scholar 

  • Ged EC, Boyer TH (2014) Desalination 345:85–93

    Article  CAS  Google Scholar 

  • Ged EC, Chadik PA, Boyer TH (2015) J Environ Manage 149:253–262

    Article  CAS  Google Scholar 

  • Gong T, Zhang X, Li Y, Xian Q (2016) Chemosphere 149:70–75

    Article  CAS  Google Scholar 

  • Gude VG (2016) Water Res 89:87–106

    Article  CAS  Google Scholar 

  • Gude VG, Nirmalakhandan N, Deng S (2010) Desalin Water Treat 20:281–290

    Article  CAS  Google Scholar 

  • Guo L (2007) Sci New Ser 317(5842):1166

    CAS  Google Scholar 

  • Hanna-Attisha M, Lachance J, Sadler RC, Schnepp AC (2016) AJPH 106(2):283–290

    Google Scholar 

  • Harris-Lovett SR, Binz C, Sedlak DL, Kiparsky M, Truffer B (2015) Environ Sci Technol 49(13):7552–7561

    Article  CAS  Google Scholar 

  • Her N, Amy G, Park H, Song M (2004) Water Res 38:1427–1438

    Article  CAS  Google Scholar 

  • Hijnen WAM, Beerendonk EF, Medema GJ (2006) Water Res 40:3–22

    Google Scholar 

  • Hoagland AP, Anderson DM, Kaoru Y, White AW (2002) Estuaries 25(4):819–837

    Article  Google Scholar 

  • Hoeger SJ, Hitzfeld BC, Dietrich DR (2005) Toxicol Appl Pharmacol 203:231–242

    Article  CAS  Google Scholar 

  • Hrudey SE (2009) Water Res 43:2057–2092

    Article  CAS  Google Scholar 

  • Hrudey SE, Hrudey EJ (2014) Ensuring safe drinking water: learning from frontline experience with contamination. American Water Works Association, Denver

    Google Scholar 

  • Hrudey SE, Backer LC, Humpage AR, Krasner SW, Michaud DS, Moore LE, Singer PC, Stanford BD (2015) J Toxicol Environ Heal Part B Crit Rev 18(5):213–241

    Google Scholar 

  • Hua G, Reckhow DA, Kim J (2006) Environ Sci Technol 40(9):3050–3056

    Article  CAS  Google Scholar 

  • Huber MM, Korhonen S, Ternes TA, Von Gunten U (2005) Water Res 39(15):3607–3617

    Article  CAS  Google Scholar 

  • Ibelings BW, Bormans M, Fastner J, Visser PM (2016) Aquat Ecol 50(3):595–605

    Article  CAS  Google Scholar 

  • International Agency for Research on Cancer (1978) IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: some N-nitroso compounds

    Google Scholar 

  • Ireland Environmental Protection Agency (2011) Water treatment manual: disinfection. Wexford, Ireland

    Google Scholar 

  • Jiang J, Zhang X, Zhu X, Li Y (2017) Environ Sci Technol 51:3435–3444

    Article  CAS  Google Scholar 

  • Kim EJ, Herrera JE (2010) Environ Sci Technol 44(16):6054–6061

    Article  CAS  Google Scholar 

  • Kim I, Yamashita N, Tanaka H (2009) J Hazard Mater 166(2–3):1134–1140

    Article  CAS  Google Scholar 

  • Kim D, Amy GL, Karanfil T (2015) Water Res 81:343–355

    Article  CAS  Google Scholar 

  • Kimura K, Amy G, Drewes JE, Heberer T, Kim TU, Watanabe YJ (2003) Memb Sci 227(1–2):113–121

    Article  CAS  Google Scholar 

  • Kimura SY, Komaki Y, Plewa MJ (2013) Environ Sci Technol 47:12382–12390

    Article  CAS  Google Scholar 

  • Knappe DRU (2006) Interface science and technology. Elsevier, New York, pp 155–177

    Google Scholar 

  • Krasner SW (2009) Philos Trans R Soc A Math Phys Eng Sci 367:4077–4095

    Google Scholar 

  • Krasner SW, Weinberg HS, Richardson SD, Pastor SJ, Chinn R, Sclimenti MJ, Onstad GD, Thruston AD (2006) Environ Sci Technol 40(23):7175–7185

    Article  CAS  Google Scholar 

  • Krasner SW, Westerhoff P, Chen B, Rittmann BE, Nam S-N, Amy G (2009) 43:2911–2918

    Google Scholar 

  • Krasner SW, Mitch WA, McCurry DL, Hanigan D, Westerhoff P (2013) Water Res 47(13):4433–4450

    Article  CAS  Google Scholar 

  • Krasner SW, Lee TCF, Westerhoff P, Fischer N, Hanigan D, Karanfil T, Beita-Sandí W, Taylor-Edmonds L, Andrews RC (2016) Environ Sci Technol 50(17):9583–9591

    Article  CAS  Google Scholar 

  • Kristiana I, Charrois JWA, Hrudey SE (2012) Disinfection by-products. In: Hrudey SE, Charrois JWA (eds) IWA Publishing, London, U.K., pp 11–39

    Google Scholar 

  • Landsberg JH (2002) Rev Fish Sci 10(2):113–390

    Article  Google Scholar 

  • Lee H, Tan TP (2016) Int J Water Resour Dev 32(4):611–621

    Google Scholar 

  • Lee Y, von Gunten U (2010) Water Res 44(2):555–566

    Article  CAS  Google Scholar 

  • Levy K, Woster AP, Goldstein RS, Carlton E (2017) J Environ Sci Technol 50(10):4905–4922

    Article  CAS  Google Scholar 

  • Li X-F, Mitch WA (2018) Environ Sci Technol 52:1681–1689

    Article  CAS  Google Scholar 

  • Li J, Moe B, Vemula S, Wang W, Li XF (2016) Environ Sci Technol 50(13):6744–6752

    Article  CAS  Google Scholar 

  • Linge KL, Blythe JW, Busetti F, Blair P, Rodriguez C, Heitz A (2013) Sep Purif Technol 104:221–228

    Article  CAS  Google Scholar 

  • Liteplo RG, Meek ME, Windle W (2002) N-nitrosodimethylamine: concise international chemical assessment document 38. Stuttgart, Germany

    Google Scholar 

  • Liu W, Andrews SA, Bolton JR, Kinden KG, Sharpless C, Stefan M (2002) Water Supply 2(5–6):515–521

    Article  Google Scholar 

  • Liu W, Cheung L, Yang X, ÃCS (2006) 40:2033–2043

    Google Scholar 

  • Liu C, Olivares CI, Pinto AJ, Lauderdale CV, Brown J, Selbes M, Karanfil T (2017) Water Res 124:630–653

    Article  CAS  Google Scholar 

  • Mackie AL, Park YR, Gagnon GA (2017) Environ Sci Technol 51:10711–10717

    Article  CAS  Google Scholar 

  • Magee PN, Barnes JM (1967) Advances in cancer research. In: Haddow A, Weinhouse S (eds) Academic Press, pp 163–246

    Google Scholar 

  • Marron EL, Mitch WA, Gunten UV, Sedlak DL (2019) Acc Chem Res 52(3):615–622

    Google Scholar 

  • Masten SJ, Davies SH, Mcelmurry SP (2017) J Am Water Work Assoc 108(12):22–34

    Google Scholar 

  • McCurry DL, Quay AN, Mitch WA (2016) Environ Sci Technol 50(3):1209–1217

    Article  CAS  Google Scholar 

  • Mcguire MJ, Meadow RG (1988) J Am Water Work Assoc 80(1):61–68

    Article  CAS  Google Scholar 

  • Mekonnen MM, Hoekstra AY (2016) Sci Adv 2(2):1–7

    Article  Google Scholar 

  • Michalak AM, Anderson EJ, Beletsky D, Boland S, Bosch NS, Bridgeman TB, Chaffin JD, Cho K, Confesor R, Daloglu I, DePinto JV, Evans MA, Fahnenstiel GL, He L, Ho JC, Jenkins L, Johengen TH, Kuo KC, LaPorte E, Liu X, McWilliams MR, Moore MR, Posselt DJ, Richards RP, Scavia D, Steiner AL, Verhamme E, Wright DM, Zagorski MA (2013) Proc Natl Acad Sci 110(16):6448–6452

    Article  CAS  Google Scholar 

  • Michigan Department of Health and Human Services GCPHD (2015a) Legionellosis outbreak-genesee county, June, 2014-November, 2015 summary analysis

    Google Scholar 

  • Michigan Department of Health and Human Services GCPHD (2015b) Legionellosis outbreak-genesee county, May, 2014-March, 2015 full analysis

    Google Scholar 

  • Muellner MG, Wagner ED, Mccalla K, Richardson SD, Woo YT, Plewa M (2007) J Environ Sci Technol 41(2):645–651

    Article  CAS  Google Scholar 

  • Narotsky MG, Klinefelter GR, Goldman JM, Deangelo AB, Best DS, Mcdonald A, Strader LF, Murr AS, Suarez JD, George MH, Hunter ES, Simmons JE (2015) Environ Heal Perspect 123(6):564–570

    Article  CAS  Google Scholar 

  • National Research Council (2012) Water reuse: potential for expanding the nation’s water supply through reuse of municipal wastewater. The National Academies Press, Washington, DC

    Google Scholar 

  • National Cancer Institute (1976) Carcinogenesis bioassay of chloroform. Bethesda, MD

    Google Scholar 

  • Negreira N, Regueiro J (2015) Water Res 85:103–113

    Article  CAS  Google Scholar 

  • Nika M-C, Bletsou AA, Koumaki E, Noutsopoulos C, Mamais D, Stasinakis AS, Thomaidis NS (2017) J Hazard Mater 323:400–413

    Article  CAS  Google Scholar 

  • Pals J, Attene-Ramos MS, Xia M, Wagner ED, Plewa M (2013) J Environ Sci Technol 47(21):12514–12523

    Article  CAS  Google Scholar 

  • Parker KM, Zeng T, Harkness J, Vengosh A, Mitch WA (2014) Environ Sci Technol 48(19):11161–11169

    Article  CAS  Google Scholar 

  • People’s Republic of China (2006) Standards for drinking water quality, GB5749-2006. Beijing, China.

    Google Scholar 

  • Pieper KJ, Tang M, Edwards MA (2017) Environ Sci Technol 51:2007–2014

    Article  CAS  Google Scholar 

  • Pinkernell U, von Gunten U (2001) Environ Sci Technol 35:2525–2531

    Article  CAS  Google Scholar 

  • Plewa MJ, Wagner ED, Muellner MG, Hsu K-M, Richardson SD (2008) Disinfection by-products in drinking water. Occur. Form. Health Eff. Control 995(7):36–50

    Google Scholar 

  • Plewa MJ, Simmons JE, Richardson SD, Wagner ED (2010) Environ Mol Mutagen 51(8–9):871–878

    Article  CAS  Google Scholar 

  • Plewa MJ, Simmons JE, Richardson SD, Wagner ED (2014) Environ Mol Mutagen 51:871–878

    Article  CAS  Google Scholar 

  • Plewa MJ, Wagner ED, Richardson SD (2017) J Environ Sci 58:208–216

    Article  Google Scholar 

  • Plummer JD, Edzwald JK (2001) Environ Sci Technol 35(18):3661–3668

    Article  CAS  Google Scholar 

  • Qian Y, Wu M, Wang W, Chen B, Zheng H, Krasner SW, Hrudey SE, Li XF (2015) Anal Chem 87(2):1330–1336

    Article  CAS  Google Scholar 

  • Qin B, Zhu G, Gao G, Zhang Y, Li W, Paerl HW, Carmichael WW (2010) Env Manage 45:105–112

    Google Scholar 

  • Rabin R (2008) Am J Public Health 98(9):1584–1592

    Article  Google Scholar 

  • Radjenović J, Petrović M, Ventura F, Barceló D (2008) Water Res 42(14):3601–3610

    Article  CAS  Google Scholar 

  • Rhoads WJ, Pruden A, Edwards MA (2017) Environ Sci Technol 51(12):7065–7075

    Google Scholar 

  • Richardson SD (2011) Encyclopedia of environmental health. In: Nriagu JO (ed). Elsevier Inc., pp 110–136

    Google Scholar 

  • Richardson SD, Kimura SY (2017) Environ Technol Innov 8:40–56

    Article  Google Scholar 

  • Richardson SD, Ternes TA (2018) Anal Chem 90(1):398–428

    Article  CAS  Google Scholar 

  • Richardson SD, Thruston AD, Rav-Acha C, Groisman L, Popilevsky I, Juraev O, Glezer V, McKAgue AB, Plewa MJ, Wagner ED (2003) Environ Sci Technol 37(17):3782–3793

    Article  CAS  Google Scholar 

  • Richardson SD, Plewa MJ, Wagner ED, Schoeny R, Demarini DM (2007) Mutat Res 636:178–242

    Article  CAS  Google Scholar 

  • Richardson SD, Fasano F, Ellington JJ, Crumley FG, Buettner KM, Evans JJ, Blount BC, Silva LK, Waite TIMJ, Luther GW, Mckague AB, Miltner RJ, Wagner ED, Plewa MJ (2008) Environ Sci Technol 42(22):8330–8338

    Google Scholar 

  • Roberts DA, Johnston EL, Knott NA (2010) Water Res 44(18):5117–5128

    Article  CAS  Google Scholar 

  • Rook J (1974) Water Treat Exam 23:234–243

    Google Scholar 

  • Rosen MB, Pokhrel LR, Weir MH (2017) Sci Total Environ 590–591:843–852

    Article  CAS  Google Scholar 

  • Rostkowska K, Zwierz K, Rozanski A, Moniuszko-Jakoniuk J, Roszczenko A (1998) Pol J Environ Stud 7:321–325

    CAS  Google Scholar 

  • Sakai H, Hao A, Iseri Y, Wang S, Kuba T, Zhang Z, Katayama H (2013) Sci World J

    Google Scholar 

  • Saleh NB, Apul O, Karanfil T (2019) Environ Sci Technol 53:1746–1747

    Article  CAS  Google Scholar 

  • Savitz DA, Singer PC, Herring AH, Hartmann KE, Weinberg HS, Makarushka C (2006) Am J Epidemiol 164(11):1043–1051

    Article  Google Scholar 

  • Scanlan RA, Issenberg P (1975) CRC Crit Rev Food Sci Nutr 5:357–402

    CAS  Google Scholar 

  • Schreiber IM, Mitch WA (2006) Environ Sci Technol 40(19):6007–6014

    Article  CAS  Google Scholar 

  • Sedlak DL (2019) Environ Sci Technol 53:3999–4000

    Article  CAS  Google Scholar 

  • Seidel CJ, McGuire MJ, Summers RS, Via S (2005) J Am Water Work Assoc 97(10):87–97

    Article  CAS  Google Scholar 

  • Semiat R (2000) Water Int 25(1):54–65

    Article  CAS  Google Scholar 

  • Shah AD, Mitch WA (2012) Environ Sci Technol 46(1):119–131

    Article  CAS  Google Scholar 

  • Shah AD, Dotson AD, Linden KG, Mitch WA (2011) Environ Sci Technol 45:3657–3664

    Google Scholar 

  • Shah AD, Krasner SW, Lee CFT, von Gunten U, Mitch WA (2012) Environ Sci Technol 46(9):4809–4818

    Article  CAS  Google Scholar 

  • Smeets PWMH, Medema GJ, van Dijk JC (2009) Drink Water Eng Sci 2:1–14

    Article  CAS  Google Scholar 

  • Snyder SA, Adham S, Redding AM, Cannon FS, DeCarolis J, Oppenheimer J, Wert EC, Yoon Y (2007) Desalination 202(1–3):156–181

    Article  CAS  Google Scholar 

  • Song L, Chen W, Peng L, Wan N, Gan N, Zhang X (2007) Water Res 41:2853–2864

    Article  CAS  Google Scholar 

  • Souliotis VL, Henneman JR, Reed CD, Chhabra SK, Diwan BA, Anderson LM, Kyrtopoulos SA (2002) Mutat Res Fundam Mol Mech Mutagen 500(1–2):75–87

    Article  CAS  Google Scholar 

  • Stikker A (2002) Water Policy 4:47–55

    Article  Google Scholar 

  • Stroom JM, Kardinaal WEA (2016) Aquat Ecol 50(3):541–576

    Article  CAS  Google Scholar 

  • Summers RS, Benz MA, Shukairy MH, Cummings L (1993) J Am Water Work Assoc 85(1):88–95

    Article  CAS  Google Scholar 

  • Summers RS, Knappe DRU, Snoeyink VL (2010) Water quality and treatment. American Water Works Association McGraw-Hill, New York

    Google Scholar 

  • Sun Y, Chen Z, Wu G, Wu Q, Zhang F, Niu Z, Hu HY (2016) J Clean Prod 131:1–9

    Article  CAS  Google Scholar 

  • Sutherland IW (1985) Ann Rev Microbiol 39:243–270

    Article  CAS  Google Scholar 

  • Symons JM (1975) National organics reconnaissance survey. Preliminary assessment of suspected carcinogens in drinking water (Appendices). Washington, DC

    Google Scholar 

  • Symons JM, Krasner SW, Simms LA, Sclimenti M (1993a) Am Water Work Assoc 85(1):51–62

    Article  CAS  Google Scholar 

  • Symons JM, Krasner SW, Simms LA, Sclimenti MJ (1993b) J Am Water Work Assoc 85(1):51–62

    Article  CAS  Google Scholar 

  • Szczuka A, Parker KM, Harvey C, Hayes E, Vengosh A, Mitch WA (2017) Water Res 122:633–644

    Article  CAS  Google Scholar 

  • Szczuka A, Berglund-Brown JP, Chen HK, Quay AN, Mitch WA (2019) Environ Sci Technol 53(6):3166–3176

    Article  CAS  Google Scholar 

  • Taguchi V, Jenkins SDW, Wang DT, Palmentier JPFP, Reiner EJ (1994) Can J Appl Spectrosc 39(3):87–93

    CAS  Google Scholar 

  • Tang CY, Fu QS, Robertson AP, Criddle CS, Leckie JO (2006) Environ Sci Technol 40(23):7343–7349

    Article  CAS  Google Scholar 

  • Tardiff RG, Carson ML, Ginevan ME (2006) Regul Toxicol Pharmacol 45(2):185–205

    Article  CAS  Google Scholar 

  • Ternes TA, Stüber J, Herrmann N, McDowell D, Ried A, Kampmann M, Teiser B (2003) Water Res 37(8):1976–1982

    Article  CAS  Google Scholar 

  • Trebse P, Polyakova OV, Baranova M, Kralj MB, Dolenc D, Sarakha M, Kutin A, Lebedev AT (2016) Water Res 101:95–102

    Article  CAS  Google Scholar 

  • Trueman BF, Krkosek WH, Gagnon GA (2018) Environ Sci Water Res 4:505–512

    Article  CAS  Google Scholar 

  • US Environmental Protection Agency (2006) Fed Regist 71:388–493

    Google Scholar 

  • Vengosh A (2014) Salinization and saline environments, 2nd edn. Elsevier ltd

    Google Scholar 

  • von Gunten U (2003a) Water Res 37:1443–1467

    Article  CAS  Google Scholar 

  • von Gunten U (2003b) Water Res 37:1469–1487

    Article  CAS  Google Scholar 

  • Wagner ED, Plewa MJ (2017) J Environ Sci 58:64–76

    Article  Google Scholar 

  • Wang C, Shang C, Ni M, Dai J, Jiang F (2012a) Environ Sci Technol 46(17):9398–9405

    Article  CAS  Google Scholar 

  • Wang Z, Kim J, Seo Y (2012b) Environ Sci Technol 46(20):11361–11369

    Article  CAS  Google Scholar 

  • Wang J, Liu X, Wai T, Xiao J, Chow AT, Keung P (2013) Water Res 47(8):2701–2709

    Article  CAS  Google Scholar 

  • Wang W, Qian Y, Li J, Moe B, Huang R, Zhang H, Hrudey SE, Li XF (2014) Anal Chem 86(10):4982–4988

    Article  CAS  Google Scholar 

  • Washington State Department of Health. Alternate Disinfectants. https://www.doh.wa.gov/CommunityandEnvironment/DrinkingWater/Disinfection/DisinfectionByproducts/DisinfectantsandDisinfectionByproducts/AlternateDisinfectants. Accessed May 27, 2019

  • Wei Y, Liu Y, Zhang Y, Dai R, Liu X, Wu J, Zhang Q (2011) Environ Sci Pollut Res 18:46–50

    Article  CAS  Google Scholar 

  • Westerhoff P, Mash H (2002) J Water Supply Res Technol AQUA 51(8):415–448

    Google Scholar 

  • Westerhoff P, Chao P, Mash H (2004) Water Res 38(6):1502–1513

    Article  CAS  Google Scholar 

  • World Health Organization (2017) Guidelines for drinking-water quality: incorporating the first addendum, 4th edn. WHO Press, Geneva, Switzerland

    Google Scholar 

  • World Health Organization (2009) Global health risks: mortality and burden of disease attributable to selected major risks. WHO Press, Geneva, Switzerland

    Google Scholar 

  • World Health Organization, UNICEF (2017) Main report progress on drinking water, sanitation and hygiene: 2017 update and SDG baselines

    Google Scholar 

  • Yang M, Liberatore HK, Zhang X (2019) Curr Opin Environ Sci Heal 7:98–107

    Article  Google Scholar 

  • Zahran S, Mcelmurry SP, Kilgore PE, Mushinski D, Press J, Love NG, Sadler RC, Swanson MS (2018) Proc Natl Acad Sci 115(25):5835

    Article  Google Scholar 

  • Zeng T, Plewa MJ, Mitch WA (2016) Water Res 101:176–186

    Article  CAS  Google Scholar 

  • Zhang Y, Chu W, Yao D, Yin D (2017) J Environ Sci 58:322–330

    Article  Google Scholar 

  • Zhao Y, Boyd J, Hrudey SE, Li X-F (2006) Environ Sci Technol 40(24):7636–7641

    Google Scholar 

  • Zhao Y-Y, Boyd JM, Woodbeck M, Andrews RC, Qin F, Hrudey SE, Li X-F (2008) Environ Sci Technol 42(13):4857–4862

    Article  CAS  Google Scholar 

  • Zhao Z, Zuo J, Zillante G (2017) J Clean Prod 163:136–145

    Article  Google Scholar 

  • Ziervogel G (2019) Unpacking the Cape Town drought: lessons learned

    Google Scholar 

Download references

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Authors and Affiliations

  1. Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2G3, Canada

    Nicholas Wawryk, Di Wu, Angela Zhou, Birget Moe & Xing-Fang Li

  2. Alberta Centre for Toxicology, Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada

    Birget Moe

Authors
  1. Nicholas Wawryk
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  2. Di Wu
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  3. Angela Zhou
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  4. Birget Moe
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  5. Xing-Fang Li
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Corresponding authors

Correspondence to Birget Moe or Xing-Fang Li .

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Editors and Affiliations

  1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing, China

    Guibin Jiang

  2. Department of Civil and Environmental Engineering, Faculty of Construction and Environment, The Hong Kong Polytechnic University, Hong Kong, China

    Xiangdong Li

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Wawryk, N., Wu, D., Zhou, A., Moe, B., Li, XF. (2020). Disinfection: A Trade-Off Between Microbial and Chemical Risks. In: Jiang, G., Li, X. (eds) A New Paradigm for Environmental Chemistry and Toxicology. Springer, Singapore. https://doi.org/10.1007/978-981-13-9447-8_13

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