Abstract
Water-borne infectious diseases are the major threats to the population living in the developing countries. Treatment of water-associated infectious diseases mainly involves patient care and supportive therapy which includes the symptomatic management of the diseases. Numerous drugs are undergoing clinical trials to evaluate their efficacy against several water-associated infections but still there is an unmet gap. For bacterial and parasitic infections, antibiotics are given and found to be effective against these infections whereas in most cases of viral infections no licensed antiviral drug is available. But the development of multiple drug resistance in water-associated pathogens has posed new challenge for the complete management of these infections. World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) have recommended various guidelines for the treatment and prevention of water-associated infectious pathogens using drugs and vaccines which are the most robust and promising way to restrict these infections. Some of the vaccines available are against water-associated infectious diseases such as malaria vaccine: Mosquirix or also known as RTS, S/AS01 (RTS, S); typhoid vaccine: inactivated vaccine given as a shot; live attenuated vaccine given orally; oral cholera vaccines (OCV); oral polio vaccine; and dengue vaccine: Dengvaxia, DENVax. The drugs approved for the treatment of these diseases include doxycycline for cholera, miltefosine for amoebic meningoencephalitis, azithromycin for Campylobacter jejuni, and nitazoxanide for cryptosporidiosis.
*Contributed equally as first author
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References
Centers for Disease Control and Prevention (CDC) (2017) Typhoid and paratyphoid fever, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-totravel/typhoid-paratyphoid-fever. Accessed on 12-10-2018
World Health Organization (2018) Immunization, vaccines and biologicals for Typhoid fever, 11 Sept 2018. http://www.who.int/immunization/diseases/typhoid/en/. Accessed on 12-10-2018
World Health Organization (2018) Media centre for Typhoid fever, Jan 2018. http://www.who.int/mediacentre/factsheets/typhoid/en/. Accessed on 12-10-2018
World Health Organization (2005) Guidelines for the control of shigellosis, including epidemics due to Shigella dysenteriae type 1. http://apps.who.int/iris/bitstream/handle/10665/43252/9241592330.pdf;jsessionid=B90A37B7E7B0812CE876C762E438CEBA?sequence=1. Accessed on 12-10-2018
Centers for Disease Control and Prevention (2018) Diagnosis and treatment of Shigellosis, 7 Jun 2018. https://www.cdc.gov/shigella/diagnosistreatment.html. Accessed on 12-10-2018
Centers for Disease Control and Prevention (CDC) (2015) Treatment of cholera, 20 Jan 2015. https://www.cdc.gov/cholera/treatment/antibiotic-treatment.html. Accessed on 13-10-2018
World Health Organization (2018) Oral cholera vaccines for the prevention of cholera, 1 Feb 2018. http://www.who.int/news-room/fact-sheets/detail/cholera. Accessed on 13-10-2018
WHO (2004) Cholera outbreak: assessing the outbreak response and improving preparedness. http://www.who.int/cholera/publications/final%20outbreak%20booklet%20260105-OMS.pdf. Accessed on 13-10-2018
PAHO (2010) Recommendations for clinical management of cholera, 4 Nov 2010. www.paho.org/hq/dmdocuments/2011/cholera-clin-management-ENG-rev-JUN-1.pdf. Accessed on 13-10-2018
Cholera Outbreak Training and Shigellosis (COTS) program (2018). http://www.cotsprogram.com. Accessed on 13-10-2018
Médecins Sans Frontières (2004) Cholera guidelines, 2nd edn. http://www.bvsde.paho.org/texcom/cd045364/choleraguide.pdf. Accessed on 13-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Treatment of Enteropathogenic E. coli, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/escherichia-coli-diarrheagenic. Accessed on 13-10-2018
Vila J, Ruiz J, Gallardo F, Vargas M, Soler L, Figueras MJ et al (2003) Aeromonas spp. and Traveler’s diarrhea: clinical features and antimicrobial resistance. Emerg Infect Dis 9(5):552–555. https://doi.org/10.3201/eid0905.020451
Centers for Disease Control and Prevention (CDC) (2017) Leishmaniasis, cutaneous Legionellosis (Legionnaires’ Disease & Pontiac Fever), 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/legionellosis-legionnaires-disease-pontiac-fever. Accessed on 14-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Hand foot, & mouth disease, 12 Jun 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/hand-foot-and-mouth-disease. Accessed on 14-10-2018
Centers for Disease Control and Prevention (CDC) (2019) Hand, foot, and mouth disease: prevention & treatment. www.cdc.gov/hand-foot-mouth/about/prevention-treatment.html. Accessed on 22-07-2019
Irani DN (2008) Aseptic meningitis and viral myelitis. Neurol Clin 26(3):635–655, vii–viii. https://doi.org/10.1016/j.ncl.2008.03.003
Sagar S, Liu PP, Cooper LT Jr (2012) Myocarditis. Lancet 379(9817):738–747. https://doi.org/10.1016/S0140-6736(11)60648-X
Centers for Disease Control and Prevention (CDC) (2018) Viral Meningitis: prevention and treatment, 31 Jul 2018. https://www.cdc.gov/meningitis/viral.html. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2016) Yersinia enterocolitica (Yersiniosis): information for health & lab professionals, 25 May 2016. https://www.cdc.gov/yersinia/healthcare.html. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2016) Yersinia enterocolitica (Yersiniosis): diagnosis and treatment, 26 May 2016. https://www.cdc.gov/yersinia/diagnosis.html. Accessed on 15-10-2018
World Health Organization (2018) Campylobacter: prevention and treatment, 23 Jan 2018. http://www.who.int/news-room/fact-sheets/detail/campylobacter. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Campylobacteriosis: diagnosis and treatment, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/campylobacteriosis. Accessed on 15-10-2018
Giamarellou H (2000) Therapeutic guidelines for Pseudomonas aeruginosa infections. Int J Antimicrob Agents 16(2):103–106
Centers for Disease Control and Prevention (CDC) (2017) Leptospirosis: prevention and treatment, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/leptospirosis. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2018) Leptospirosis: fact sheet for clinicians, 23 Jan 2018. https://www.cdc.gov/leptospirosis/pdf/fs-leptospirosis-clinicians-eng-508.pdf. Accessed on 15-10-2018
Chey WD, Wong BC, Practice Parameters Committee of the American College of Gastroenterology (2007) American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol 102(8):1808–1825
Centers for Disease Control and Prevention (CDC) (2017) Helicobacter pylori: diagnosis and treatment, 12 Jun 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/helicobacter-pylori. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Poliomyelitis: prevention and treatment, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/poliomyelitis. Accessed on 15-10-2018
World Health Organization (2017) Poliomyelitis: immunization, vaccines and biologicals, 9 Feb 2017. https://www.who.int/immunization/diseases/poliomyelitis/en/. Accessed on 15-10-2018
Parashar UD, Nelson EA, Kang G (2013) Diagnosis, management, and prevention of rotavirus gastroenteritis in children. BMJ 347:f7204. https://doi.org/10.1136/bmj.f7204
World Health Organization (2018) Rotavirus: immunization, vaccines and biologicals, Nov 2018. https://www.who.int/immunization/diseases/rotavirus/en/. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2018) Adenoviruses: prevention & treatment, 26 Apr 2018. https://www.cdc.gov/adenovirus/hcp/prevention-treatment.html. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Hepatitis A: prevention & treatment, 29 Sept 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/hepatitis-a. Accessed on 15-10-2018
World Health Organization (2018) Hepatitis A: prevention & treatment, 19 Sept 2018. http://www.who.int/news-room/fact-sheets/detail/hepatitis-a. Accessed on 15-10-2018
World Health Organization (2018) Hepatitis E: prevention & treatment, 19 Sept 2018. http://www.who.int/news-room/fact-sheets/detail/hepatitis-e. Accessed on 15-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Norovirus: prevention & treatment, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/norovirus. Accessed on 15-10-2018
Davies AP, Chalmers RM (2009) Cryptosporidiosis. BMJ 339:b4168. https://doi.org/10.1136/bmj.b4168
Centers for Disease Control and Prevention (CDC) (2015) Cryptosporidium: prevention & treatment, 20 Feb 2015. https://www.cdc.gov/parasites/crypto/treatment.html. Accessed on 15-10-2018.
Cope JR, Ali IK (2019) Amebiasis, Travel-Related Infectious Diseases. Centers for Disease Control and Prevention (CDC). https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectious-diseases/amebiasis. Accessed on 22-07-2019
Minetti C, Chalmers RM, Beeching NJ, Probert C, Lamden K (2016) Giardiasis. BMJ 355:i5369. https://doi.org/10.1136/bmj.i5369
Centers for Disease Control and Prevention (CDC) (2017) Naegleria fowleri: primary amebic meningoencephalitis (PAM) amebic encephalitis: prevention & treatment, 3 Aug 2017. www.cdc.gov/parasites/naegleria/treatment.html. Accessed on 15-10-2018
Pana A, Bhimji SS (2018) Amebic Meningoencephalitis. 2017 Apr 2. StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL. Available from http://www.ncbi.nlm.nih.gov/books/NBK430754/PubMed
Centers for Disease Control and Prevention (CDC) (2018) Ascariasis: resources for health professionals, 14 Feb 2018. https://www.cdc.gov/parasites/ascariasis/health_professionals/index.html#tx. Accessed on 16-10-2018
World Health Organization (2018) Overview of malaria treatment, 18 Jan 2018. https://www.who.int/malaria/areas/treatment/overview/en/. Accessed on 16-10-2018
Centers for Disease Control and Prevention (CDC) (2013) Treatment of malaria (guidelines for clinicians), Jul 2013. https://www.cdc.gov/malaria/resources/pdf/clinicalguidance.pdf. Accessed on 16-10-2018
World Health Organization (2018) Lymphatic filariasis: large-scale treatment (preventive chemotherapy), 8 Oct 2018. http://www.who.int/news-room/fact-sheets/detail/lymphatic-filariasis. Accessed on 16-10-2018
Centers for Disease Control and Prevention (CDC) (2018) Lymphatic filariasis: prevention & treatment, 27 Sept 2018. https://www.cdc.gov/parasites/lymphaticfilariasis/treatment.html. Accessed on 16-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Japanese encephalitis: prevention & treatment, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/japanese-encephalitis. Accessed on 16-10-2018
World Health Organization (2015) Japanese encephalitis: immunization, vaccines and biologicals, 9 Apr 2015. https://www.who.int/immunization/diseases/japanese_encephalitis/en/. Accessed on 16-10-2018
Centers for Disease Control and Prevention (CDC) (2017) Treatment of dengue fever, 31 May 2017. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/dengue. Accessed on 16-10-2018
World Health Organization (2018) Revised SAGE recommendation on use of dengue vaccine: immunization, vaccines and biologicals, 19 Apr 2018. https://www.who.int/immunization/diseases/dengue/revised_SAGE_recommendations_dengue_vaccines_apr2018/en/. Accessed on 16-10-2018
World Health Organization (2018) Zika virus: prevention & treatment, 20 July 2018. http://www.who.int/news-room/fact-sheets/detail/zika-virus. Accessed on 16-10-2018
Anderson JF, Rahal JJ (2002) Efficacy of interferon alpha-2b and ribavirin against West Nile virus in vitro [letter]. Emerg Infect Dis 8:107–108
Centers for Disease Control and Prevention (CDC) (2018) West Nile virus: prevention & treatment, 20 Jun 2018. https://www.cdc.gov/westnile/healthcareproviders/healthCareProvidersTreatmentPrevention.html. Accessed on 16-10-2018
Centers for Disease Control and Prevention (CDC) (2018) Yellow fever: prevention & treatment, 22 Mar 2018. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/yellow-fever. Accessed on 16-10-2018
World Health Organization. Yellow fever: International travel and health. https://www.who.int/ith/vaccines/yf/en/. Accessed on 16-10-2018
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Maurya, V.K., Kumar, S., Saxena, S.K. (2020). Conventional Treatments of Water-Associated Infectious Diseases. In: Saxena, S.K. (eds) Water-Associated Infectious Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-9197-2_11
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