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Zoonoses - Infections Affecting Humans and Animals pp 433–452Cite as

Infections With Multidrug-Resistant Bacteria—Has the Post-Antibiotic Era Arrived in Companion Animals?

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Abstract

The increasing prevalence of infectious diseases caused by drug- and multidrug-resistant pathogenic bacteria in companion animals (dogs, cats, horses), particularly in veterinary hospitals, is a worrisome development. Regarding companion animals, currently the four clinically most important groups of multidrug-resistant pathogenic bacteria are methicillin-resistant Staphylococcus (S.) aureus (MRSA), methicillin-resistant S. pseudintermedius (MRSP), Extended-ß-lactamase-producing (ESBL) Enterobacteriaceae and multidrug-resistant Acinetobacter (A.) baumannii. Infections caused by these bacteria are often associated with clinical settings and involve mostly wound, skin, ear or urinary tract infections. S. pseudintermedius is a typical cause of canine skin infections and until recently regarded as being host-specific. However, the epidemic spread of MRSP together with the changing socio-cultural interaction between companion animals and humans has already resulted in human cases of MRSP infections. Just the opposite development was observed with MRSA. Here, typical hospital-associated (HA) genotypes originating from humans spread into companion animals, now being a substantial cause of disease. In both cases, typical non-zoonotic bacteria turned into zoonotic agents. These findings are just the tip of the iceberg when it comes to the influence of antimicrobial drug usage and multidrug-resistance in speeding up microbial evolution. Concerted action is urgently needed to slow down these processes.

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Authors and Affiliations

  1. Free University Berlin, Berlin, Germany

    Lothar H. Wieler Vet, Birgit Walther, Szilvia Vincze, Sebastian Guenther & Antina Lübke-Becker

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  1. Lothar H. Wieler Vet
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  2. Birgit Walther
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  3. Szilvia Vincze
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  4. Sebastian Guenther
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  5. Antina Lübke-Becker
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Correspondence to Lothar H. Wieler Vet .

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  1. Dept. of Infectiology, Bavarian Health and Food Safety Authority, Oberschleißheim, Bayern, Germany

    Andreas Sing

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Wieler, L., Walther, B., Vincze, S., Guenther, S., Lübke-Becker, A. (2015). Infections With Multidrug-Resistant Bacteria—Has the Post-Antibiotic Era Arrived in Companion Animals?. In: Sing, A. (eds) Zoonoses - Infections Affecting Humans and Animals. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9457-2_17

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