Abstract
Monoclonal light chain deposition disease, as distinguished from light chain amyloid (AL), was first noted in renal biopsies in 1973 [1]. Its immunohistology and systemic nature were detailed in 1976 [2]. Since then approximately 90 cases of these nephropathies associated with dysproteinemias have been reported from different institutions and countries, variously termed: nodular glomerulosclerosis, nodular glomerulopathy, nonamyloidotic light chain glomerulopathy, and kappa light chain nephropathy. More recently the realization that monoclonal deposits are of several types has led us to the use of the more inclusive term — Monoclonal Immunoglobulin Deposition Disease (MIDD) — to encompass a particular spectrum of renal lesions associated with the dysproteinemias.
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© 1988 Kluwer Academic Publishers, Dordrecht
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Gallo, G., Buxbaum, J. (1988). Monoclonal Immunoglobulin Deposition Disease: Immunopathologic Aspects of Renal Involvement. In: Minetti, L., D’Amico, G., Ponticelli, C. (eds) The Kidney in Plasma Cell Dyscrasias. Developments in Nephrology, vol 22. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1315-8_16
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DOI: https://doi.org/10.1007/978-94-009-1315-8_16
Publisher Name: Springer, Dordrecht
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