Turning Upside Down the Mode of Science to Emphasize and Harness the Impact of Environmental Communication

Abstract

Bridging theory and practice remains the very own endeavor of clinicians; such bridging is aimed at expelling science from the ‘niches’ and at establishing the upside down of the scientific mode. The suggested steady on-going transition of the phenotypes of biological systems objects has become an object of institutionalized scientific interest to ultimately conceive transient evolutionarily confined systems stages or even heterogeneity among metastatic tumor sites. Providing methodologies for reconstructing the situative communicative expression of systems participators is the novel field of evolution-adjusted tumor pathophysiology. The evolution theory is based on the assumption that biological processes are interwoven with communication and represented and reproduced through communication acts to facilitate communicative expression: A tumor system not only consists of diverse cell types and pathways—termed ‘tumor systems objects’—but also comprises all components of action insofar that these components are oriented in terms of diverse cell types. The components of action are organized in communication acts. Communication within a biological system is closely linked to descriptively accessible ‘learning’ processes, contingency programming, adoption of the players, and the systems objects within a tumor system. An evolution theory should operationalize the ‘metabolism’, facilitating the spinoff of novel systems functions. Furthermore, such a theory is aimed at covering some practical, i.e., diagnostically and therapeutically relevant issues to convince the scientific community that the evolutionary concept lacks proper appreciation, both for diagnostic and therapeutic issues. For many diseases, such as metastatic tumors that have undergone countless years of evolution, a stepwise and evolution-adjusted therapy rather than drastic therapeutic interventions based on theme-dependent knowledge may be an alternative for achieving medical improvements. Thus, paradox situations of cellular rationalization, deformation, and communication processes need to be decoded or, in other words, it is necessary to uncover inconsistencies within tumor cell compartments or distinct topologies of aggregated action effects.