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Angiocentric Glioma-Induced Seizures: Lesionectomy

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Tumors of the Central Nervous System, Volume 2

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 2))

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Abstract

Glioneuronal tumors, such as dysembryoplastic neuroepithelial tumors and gangliomas, are known to induce intractable partial onset epilepsy. A recently described tumor type, angiocentric glioma, has been found to be extremely epileptogenic with seizures affecting all diagnosed patients. Individuals with complete tumor removal achieve freedom from seizure, and those with partial removal have a significant reduction in seizures. This chapter will review the complications of intractable symptomatic epilepsy, discuss medical management, and make the case proceed directly to lesionectomy, however others require further investigation prior to surgery. Identifying eloquent cortex is essential in surgical planning and minimizing post-surgical morbidity. Non-invasive and invasive techniques required to define the epiletogenic zone and identify areas of critical cortical function will be described.

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Acknowledgements

We would like to thank Dr. Jeffrey Kerr for his editorial expertise and Santa LeSure for the graphic labeling and design. Radiographic images were completed at Le Bonheur Children’s Medical Center and used with permission.

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Authors and Affiliations

  1. Division of Neurology, Department of Pediatrics, Dell Children’s Medical Center, Austin, TX, 78723, USA

    Dave F. Clarke & Timothy M. George

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  1. Dave F. Clarke
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  2. Timothy M. George
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Correspondence to Dave F. Clarke .

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Editors and Affiliations

  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Clarke, D.F., George, T.M. (2011). Angiocentric Glioma-Induced Seizures: Lesionectomy. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 2. Tumors of the Central Nervous System, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0618-7_42

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  • DOI: https://doi.org/10.1007/978-94-007-0618-7_42

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-0617-0

  • Online ISBN: 978-94-007-0618-7

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