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Plasma Levels of Thrombomodulin and Active Plasminogen Activator Inhibitor Increase in Disseminated Intravascular Coagulation with Multiple Organ Failure

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Abstract

Disseminated intravascular coagulation (DIC) is a serious clinical condition, but its pathophysiology is very different according to the underlying diseases responsible for DIG, For example, a marked activation of the coagulation and fibrinolytic system is present in most cases of acute promyelocytic leukemia. On the contrary, a little activation of the fibrinolytic system is present in most cases of sepsis with DIC1–4. Therefore, it is important to investigate these pathologic condithions separately according to the underlying disease responsible for DIC.

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References

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© 1992 Springer Japan

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Asakura, H. et al. (1992). Plasma Levels of Thrombomodulin and Active Plasminogen Activator Inhibitor Increase in Disseminated Intravascular Coagulation with Multiple Organ Failure. In: Takada, A., Budzynski, A.Z. (eds) Hemostasis and Circulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66925-8_33

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  • DOI: https://doi.org/10.1007/978-4-431-66925-8_33

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70096-8

  • Online ISBN: 978-4-431-66925-8

  • eBook Packages: Springer Book Archive

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