Abstract
Accurate and fast estimation of T1 relaxation times is a crucial ingredient for many applications in magnetic resonance imaging [1]. A fast way for T1 estimation is a model-based reconstruction from data obtained with variable flip angles as proposed in [2]. However, this technique requires multiple measurements thus patient movement can degrade the results. In this work we introduce a novel model which combines registration and T1 estimation. A discretization of the new approach is given, including a tailored optimization algorithm. The novel method is compared to conventional reconstruction techniques on 2D software phantom data. With the new method it was possible to improve the relative error in T1 maps from 0.4253 to 0.4049 using the novel algorithm.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Sourbron S. Technical aspects of MR perfusion. Eur J Radiol. 2010;76(3):304–13.
Gupta RK. A new look at the method of variable nutation angle for the measurement of spin-lattice relaxation times using fourier transform NMR. J Magn Reson. 1977;25(1):231–5.
Crawley AP, Henkelman RM. A comparison of one-shot and recovery methods in T1 imaging. Magn Reson Med. 1988;7(1):23–34.
Cheng HLM, Wright GA. Rapid high-resolutionT1 mapping by variable flip angles: accurate and precise measurements in the presence of radiofrequency field inhomogeneity. Magn Reson Med. 2006;55(3):566–74.
Buonaccorsi GA, O’Connor JP, Caunce A, et al. Tracer kinetic model–driven registration for dynamic contrast-enhanced MRI time-series data. Magn Reson Med. 2007;58(5):1010–9.
Segars W, Sturgeon G, Mendonca S, et al. 4D XCAT phantom for multimodality imaging research. Med Phys. 2010;37(9):4902–15.
Modersitzki J. FAIR: Flexible Algorithms for Image Registration. SIAM; 2009.
Chung J, Haber E, Nagy J. Numerical methods for coupled super-resolution. Inverse Probl. 2006;22(4):1261–72.
de Bazelaire CMJ, , Duhamel GD, , Rofsky NM, et al. MR imaging relaxation times of abdominal and pelvic tissues measured in Vivo at 3.0T: preliminary results. Radiology. 2004;230(3):652–9.
Henkelman RM. Measurement of signal intensities in the presence of noise in MR images. Med Phys. 1985;12(2):232–3.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Heck, C., Benning, M., Modersitzki, J. (2015). Joint Registration and Parameter Estimation of T1 Relaxation Times Using Variable Flip Angles. In: Handels, H., Deserno, T., Meinzer, HP., Tolxdorff, T. (eds) Bildverarbeitung für die Medizin 2015. Informatik aktuell. Springer Vieweg, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46224-9_38
Download citation
DOI: https://doi.org/10.1007/978-3-662-46224-9_38
Published:
Publisher Name: Springer Vieweg, Berlin, Heidelberg
Print ISBN: 978-3-662-46223-2
Online ISBN: 978-3-662-46224-9
eBook Packages: Computer Science and Engineering (German Language)