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Role of the LFA-1 Molecule in B Cell Differentiation

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Mechanisms in B-Cell Neoplasia

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 132))

Abstract

The lymphocyte function-associated antigen-1 (LFA-1) was first identified as a T cell surface antigen, and antibodies to LFA-1 have been shown to inhibit responses of T cells to antigen and/or major histocompatibility complex (MHC) molecules (Springer 1982, Krensky 1983, Ware 1983, Collins 1984, Krensky 1984, Golde 1985, Naquet 1985). However, LFA-1 molecules are also present on the surface of B cells (Davignon 1981), and the possible functional role played by B cell LFA-1 has received little attention.

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© 1986 Springer-Verlag Berlin · Heidelberg

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Bishop, G.A., Haughton, G. (1986). Role of the LFA-1 Molecule in B Cell Differentiation. In: Melchers, F., Potter, M. (eds) Mechanisms in B-Cell Neoplasia. Current Topics in Microbiology and Immunology, vol 132. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71562-4_19

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  • DOI: https://doi.org/10.1007/978-3-642-71562-4_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71564-8

  • Online ISBN: 978-3-642-71562-4

  • eBook Packages: Springer Book Archive

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