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Influence of DNA Complexing Compounds on the Kinetoplast of Trypanosomatids

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Progress in Molecular and Subcellular Biology

Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 6))

Abstract

The members of the family Trypanosomatidae are parasitic flagellates, some of which are the causative agents of several important human and animal diseases (Hoare, 1972; Simpson, 1972). These parasites and other members of the order Kinetoplastida (Honigberg et al., 1964) contain a characteristic Feulgen-positive granule, the kinetoplast, at the base of the flagellum adjacent to the kinetosome. The presence of DNA in the kinetoplast has been confirmed (Cosgrove and Anderson, 1954; Steinert et al., 1958; Steinert and Steinert, 1962; Hill and Anderson, 1969) and its mitochondrial nature firmly established (Shipley, 1916; Clark and Wallace, 1960; Steinert, 1960; Cosgrove, 1966b; Simpson, 1972; Paulin, 1975).

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  1. S. L. Hajduk
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  1. Division of Biochemistry, Walter Reed Army Institute of Research, Washington, D.C., 20012, USA

    Fred E. Hahn Ph. D.

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Hajduk, S.L. (1978). Influence of DNA Complexing Compounds on the Kinetoplast of Trypanosomatids. In: Hahn, F.E., Kersten, H., Kersten, W., Szybalski, W. (eds) Progress in Molecular and Subcellular Biology. Progress in Molecular and Subcellular Biology, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66856-2_4

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