Skip to main content

Das Verdauungssystem

  • Chapter
  • First Online:
Altern
  • 8154 Accesses

Zusammenfassung

Das menschliche Verdauungssystem besteht aus der Mundhöhle mit Zunge und Zähnen, der Speiseröhre (Ösophagus), dem Magen, Dünndarm (Duodenum, Jejunum und Ileum), dem Dickdarm (Kolon) und Enddarm (Rektum). Es handelt sich dabei um ein durchgehendes Hohlraumsystem vom Mund zum After, in dem die wesentlichen Funktionen stattfinden: Zerkleinerung von Nahrung, ihr Transport, Speicherung (Magen, Dickdarm), die biochemische Aufspaltung der Nahrungsbestandteile, die Abtötung von aufgenommenen Bakterien und die Absorption der niedermolekularen Nahrungsbestandteile. Außerdem werden Wasser und Mineralien im Dünndarm sowohl aufgenommen wie abgegeben; Flüssigkeitsresorption und vor allem bakterielle Verarbeitung der Nahrungsreste (u. a. Vitamin-K-Produktion) finden im Dickdarm statt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 69.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Altman DF (1990) Changes in gastrointestinal, pancreatic, biliary, and hepatic function with aging. Gastroenterol Clin North Am 19:227–234

    PubMed  CAS  Google Scholar 

  • Bartlett D, Dugmore C (2008) Pathological or physiological erosion – is there a relationship to age? Clin Oral Investig 12(Suppl 1):27–31

    Article  Google Scholar 

  • Bhutto A, Morley JE (2008) The clinical significance of gastrointestinal changes with aging. Curr Opin Clin Nutr Metal Care 11:651–660

    Article  CAS  Google Scholar 

  • Braidy N, Guillemin GJ, Mansour H et al (2011) Age related changes in NAD + metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 6:e19194

    Article  PubMed  CAS  Google Scholar 

  • Cnop M, Igoillo-Esteve M, Hughes SJ, Walker JN, Cnop I, Clark A (2011) Longevity of human islet α- and β-cells. Diabetes Obes Metab 13(Suppl 1):39–46

    Article  PubMed  CAS  Google Scholar 

  • Corazza GR, Frazzoni M, Gatto MR, Gasbarini G (1986) Ageing and small-bowel mucosa: a morphometric study. Gerontology 32:60–65

    Article  PubMed  CAS  Google Scholar 

  • Dundas SR, Lawrie LC, Rooney PH, Murray GI (2005) Mortalin is overexpressed by colorectal cancer and correlates with poor survival. J Pathol 205:74–81

    Article  PubMed  CAS  Google Scholar 

  • El-Serag H, Siegel A, Davila J et al (2006) Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: a population based study. J Hepatol 44:158–166

    Article  PubMed  Google Scholar 

  • Franceschi M, Di Mario F, Leandro G, Maggi S, Pilotto A (2009) Acid-related disorders in the elderly. Best Pract Res Clin Gastroenterol 23:839–848

    Article  PubMed  CAS  Google Scholar 

  • Frith J, Jones D, Newton JL (2009) Chronic liver disease in an ageing population. Age Ageing 38:11–18

    Article  PubMed  Google Scholar 

  • Gomez-Pinilla PJ, Gibbons SJ, Kendrick ML, Sarr MG, Shen KR, Pozo MJ, Ordog T, Farrugia G (2010) Effects of aging on interstitial cells of Cajal in the human stomach. (Abstract). Gastroenterology 138:311–312

    Google Scholar 

  • Gonsalves WC, Wrightson AS, Henry RG (2008) Common oral conditions in older persons. Am Fam Physician 78:845–852

    PubMed  Google Scholar 

  • Hartmann D, Srivastava U, Thaler M (2011) Telomerase gene mutations are associated with cirrhosis formation. Hepatology 53:1608–1617

    Article  PubMed  CAS  Google Scholar 

  • Haruma K, Kamada T, Kawaguchi H et al (2000) Effect of age and Helicobacter pylori infection on gastric acid secretion. J Gastroenterol Hepatol 15:277–283

    Article  PubMed  CAS  Google Scholar 

  • Hoffmann JC, Zeitz M (2002) Small bowel disease in the elderly: diarrhoea and malabsorption. Best Pract Res Clin Gastroenterol 16:17–36

    Article  PubMed  Google Scholar 

  • Holt PR (2001) Diarrhea and malabsorption in the elderly. Gastroenterol Clin North Am 30:427–444

    Article  PubMed  CAS  Google Scholar 

  • Huttner EA, Machado DC, de Oliveira RB, Antunes AG, Hebling E (2009) Effects of human aging on periodontal tissues. Spec Care Dentist 29:149–155

    Article  PubMed  Google Scholar 

  • Izbeki F, Asuzu DT, Lorincz A, Bardsley MR, Popko LN, Choi KM, Young DL, Hayashi Y, Linden DR, Kuro-O M, Farrugia G, Ordog T (2010) Loss of Kitlow progenitors, reduces stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice. J Physiol 588:3101–3117

    Article  PubMed  CAS  Google Scholar 

  • Jin J, Wang GL, Timchenko L, Timchenko NA (2009) GSK3beta and aging liver. Aging 1:582–585

    PubMed  CAS  Google Scholar 

  • Köneke C (2005) Die interdisziplinäre Therapie der Craniomandibulären Dysfunktion. Quintessenz, Berlin

    Google Scholar 

  • Lader CS, Flanagan AM (1998) Prostaglandin E2, interleukin 1 alpha, and tumor necrosis factor-alpha increase human osteoclast formation and bone resorption in vitro. Endocrinology 139:3157–3164

    Article  PubMed  CAS  Google Scholar 

  • Lebel M, de Souza-Pinto NC, Bohr VA (2011) Metabolism, genomics, and DNA repair in the mouse aging liver. Curr Gerontol Geriatr Res 2011:859415

    PubMed  Google Scholar 

  • Madsen JL, Graff J (2004) Effects of aging on gastrointestinal motor function. Age Aging 33:154–159

    Article  Google Scholar 

  • Mamidipudi V, Chang BY, Harte RA, Lee KC, Cartwright CA (2004) RACK1 inhibits the serum- and anchorage-independent growth of v-Src transformed cells. FEBS Lett 567:321–326

    Article  PubMed  CAS  Google Scholar 

  • Meier J, Sturm A (2009) The intestinal epithelial barrier: does it become impaired with age? Dig Dis 27:240–245

    Article  PubMed  Google Scholar 

  • Morley JE (2007) The aging gut: physiology. Clin Geriatr Med 23:757–767

    Article  PubMed  Google Scholar 

  • O’Mahony D, O’Leary P, Quigley EM (2002) Aging and intestinal motility: a review of factors that affect intestinal motility in the aged. Drugs Aging 19:515–527

    Article  PubMed  Google Scholar 

  • Potter J, James O (1987) Clinical features and prognosis of alcoholic liver disease in respect of advancing age. Gerontology 33:380–387

    Article  PubMed  CAS  Google Scholar 

  • Salles N (2007) Basic mechanisms of the aging gastrointestinal tract. Dig Dis 25:112–117

    Article  PubMed  CAS  Google Scholar 

  • Salles N (2009) Is stomach spontaneously ageing? Pathophysiology of the ageing stomach. Best Pract Res Clin Gastroenterol 23:805–819

    Article  PubMed  CAS  Google Scholar 

  • Sato T, Ito K, Tamada T, Sone T et al (2011) Age-related changes in normal adult pancreas: MR imaging evaluation. Eur J Radiol 81:2093–2098

    Article  PubMed  Google Scholar 

  • Scully C, Ettinger RL (2007) The influence of systemic diseases on oral health care in older adults. J Am Dent Assoc 138(Suppl):7S–14S

    PubMed  Google Scholar 

  • Shimamoto C, Hirata I, Hiraike Y, Takeuchi N, Nomura T, Katsu K (2002) Evaluation of gastric motor activity in the elderly by electrogastrography and the (13)C-acetate breath test. Gerontology 48:381–386

    Article  PubMed  Google Scholar 

  • Stanford CM (2007) Dental implants. A role in geriatric dentistry for the general practice? J Am Dent Assoc 138(Suppl):34S–40S

    PubMed  Google Scholar 

  • Takatsu M, Uyeno S, Komura J, Watanabe M, Ono T (1999) Age-dependent alterations in mRNA level and promoter methylation of collagen alpha 1 (1) gene in human peridontal ligament. Mech Ageing Dev 110:37–48

    Article  PubMed  CAS  Google Scholar 

  • Thomson AB (2009) Small intestinal disorders in the elderly. Best Pract Res Clin Gastroenterol 23:861–874

    Article  PubMed  Google Scholar 

  • Timchenko NA (2009) Aging and liver regeneration. Trends Endocrinol Metabol 20:171–176

    Article  CAS  Google Scholar 

  • Yi H, Li XH, Yi B, Zheng J, Zhu G, Li C, Li MY, Zhang PF, Li JL, Chen ZC, Xiao ZQ (2010) Identification of Rack1, EF-Tu and Rhodanese as aging-related proteins in human colonic epithelium by proteomic analysis. J Proteome Res 9:1416–1423

    Article  PubMed  CAS  Google Scholar 

  • Zarowitz BJ (2009) Pharmacology consideration of commonly used gastrointestinal drugs in the elderly. Gastroenterol Clin North Am 38:547–562

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ludger Rensing .

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Rensing, L., Rippe, V. (2014). Das Verdauungssystem. In: Altern. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37733-4_8

Download citation

Publish with us

Policies and ethics