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Vascular Tumors Disease of the Conjunctiva

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Encyclopedia of Ophthalmology
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Synonyms

Acquired sessile hemangioma; Capillary hemangioma; Cavernous hemangioma; Glomangioma; Hemangiopericytoma; Kaposi sarcoma; Lymphangiectasia; Lymphangioma; Pyogenic granuloma; Racemose hemangioma; Varix

Definition

Benign or malignant proliferation of blood vessel endothelium that originates in either conjunctival epithelium or stroma.

Etiology

Most vascular tumors of the conjunctiva occur spontaneously (Shields et al. 2004). Kaposi sarcoma is associated with human herpesvirus 8 infection and almost exclusively seen in patients with acquired immune deficiency syndrome (Hiatt et al. 2008). Pyogenic granulomas are associated with infectious, inflammatory, or traumatic inciting events.

Clinical Presentation

Conjunctival vascular tumors are a heterogenous group of tumors with morphology dependent on the underlying cause of the tumor. The tumors can be divided into benign or malignant tumors.

A lymphangioma is a benign tumor. It can be diffused or circumscribed and generally presents...

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References

  • Hiatt KM, Nelson AM, Lichy JH, Fanburg-Smith JC (2008) Classic Kaposi Sarcoma in the United States over the last two decades: a clinicopathologic and molecular study of non-HIV-related Kaposi Sarcoma patients with comparison to HIV-related Kaposi Sarcoma. Mod Pathol 21(5):572–582. PMID: 18376387

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  • Shields CL, Shields JA (2004) Tumors of the conjunctiva and cornea. Surv Ophthalmol 49(1):3–24. Review. PMID: 14711437

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  • Shields CL, Demirci H, Karatza E et al (2004) Clinical survey of 1643 melanocytic and nonmelanocytic conjunctival tumors. Ophthalmology 111:1747–1754

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  • Shields JA, Mashayekhi A, Kligman BE et al (2011a) Vascular tumors of the conjunctiva in 140 cases. Ophthalmology 118(9):1747–1753. doi:10.1016/j.ophtha.2011.04.034, Epub 23 July 2011. PMID: 21788081

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  • Shields JA, Kligman BE, Mashayekhi A, Shields CL (2011b) Acquired sessile hemangioma of the conjunctiva: a report of 10 cases. Am J Ophthalmol 152(1):55–59.e1. doi:10.1016/j.ajo.2011.01.013, Epub 6 May 2011. PMID: 21529766

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Correspondence to Brent Betts .

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Betts, B. (2014). Vascular Tumors Disease of the Conjunctiva. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_573-1

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_573-1

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  • Online ISBN: 978-3-642-35951-4

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