Definition
p21-activated kinase 1 is a serine/threonine kinase that is activated when GTP-bound Rac or Cdc42 interacts with it. PAK1 functions to regulate the actin cytoskeleton in lamellipodia and is important in cancer cell invasion.
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© 2011 Springer-Verlag Berlin Heidelberg
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(2011). PAK1. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_4348
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DOI: https://doi.org/10.1007/978-3-642-16483-5_4348
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16482-8
Online ISBN: 978-3-642-16483-5
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