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Metabolisch und hormonell bedingte Myopathien

  • Chapter
Pathologie

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Zusammenfassung

Hier sind unter den Kohlenhydratstoffwechselstörungen die Glykogenosen, die Polyglukosankörperkrankheiten (Glykogenose Typ IV), die Danon-Krankheit und Störungen der Glykolyse abzugrenzen. Die große Zahl maternal und nukleär vererbter mitochondrialer Myopathien ist nur noch mit digitalen Verarbeitungsmethoden zu übersehen. Bei dem Myoadenylat-Deaminase-(MAD-)Mangel wird demgegenüber der Krankheitswert bezweifelt. Unter den 10 bekannten Lipidspeichermyopathien finden sich nur 4 Krankheitsbilder mit einer ausgeprägten Lipidspeicherung in den Muskelfasern, die auf Mutationen in 6 Genen beruhen. Weitere abgrenzbare Myopathien sind auf endokrine Erkrankungen z. B. der Schilddrüse (Hyper- oder Hypoparathyreoidismus) oder Hypophysenfunktionsstörungen zurückzuführen. Auch Dopingeffekte und Diabetes mellitus sind mit morphologischen Veränderungen verbunden.

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  1. Institut für Neuropathologie, Universitätsklinikum der Rheinisch-Westfälischen Technischen Hochschule (RWTH) Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland

    J. Michael Schröder

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  1. J. Michael Schröder
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  1. Institut für Pathologie Konsultationszentrum für Pankreas- und Endokrine Tumore, TU München, Ismaninger Straße 22, 81675, München, Deutschland

    Günter Klöppel (Werkherausgeber) (Werkherausgeber)

  2. Zentrum Pathologie und Rechtsmedizin, Medizinische Hochschule Hannover (MHH), Carl-Neuberg-Straße 1, 30625, Hannover, Deutschland

    Hans H. Kreipe (Werkherausgeber) (Werkherausgeber)

  3. Institut für Pathologie, Kliniken der Landeshauptstadt, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland

    Wolfgang Remmele (Werkherausgeber) (Werkherausgeber)

  4. Institut für Neuropathologie, Universitätsklinikum Münster, Domagkstraße 19, 48149, Münster, Deutschland

    Werner Paulus (Bandherausgeber) (Bandherausgeber)

  5. Institut für Neuropathologie, Universitätsklinikum der Rheinisch-Westfälischen Technischen Hochschule (RWTH) Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland

    J. Michael Schröder (Bandherausgeber) (Bandherausgeber)

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Schröder, J. (2012). Metabolisch und hormonell bedingte Myopathien. In: Klöppel, G., Kreipe, H., Remmele, W., Paulus, W., Schröder, J. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02324-8_33

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  • DOI: https://doi.org/10.1007/978-3-642-02324-8_33

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  • Print ISBN: 978-3-642-02323-1

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