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Nanoscaled biocompatible magnetic drug-delivery system: preparation and characterization

  • Conference paper
ISIAME 2008

Abstract

Biocompatible magnetic nanocomposite consisting of bovine serum albumin-based nanosized spheres hosting maghemite nanoparticle has been investigated by Mössbauer spectroscopy, X-ray diffraction, and electron microscopy. The 77 K Mössbauer spectrum was curve-fitted to two sextets whereas one doublet plus one sextet was used to fit the 300 K Mössbauer spectrum. The temperature evolution of the hyperfine parameters indicated two Mössbauer components; one associated to the core maghemite nanoparticle and the other associated to the maghemite surface shell. The 300 K quadrupole splitting value indicated strong interaction between the surface of the maghemite nanoparticle and the hosting template.

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Author information

Authors and Affiliations

  1. Instituto de Física, Núcleo de Física Aplicada, Universidade de Brasília, Brasília, DF 70910-900, Brazil

    P. C. Morais, V. K. Garg & A. C. Oliveira

  2. Departamento de Ciências Exatas e da Natureza, Fundação Universidade Federal de Rondônia, Porto Velho, RO 78961-970, Brazil

    L. B. Silveira & J. G. Santos

  3. Departamento de Química, Laboratório de Fotobiologia e Fotomedicina, Faculdade de Filosofia, Ciências e Letras, Universidade de São Paulo, Ribeirão Preto, SP 14040-901, Brazil

    M. M. A. Rodrigues & A. C. Tedesco

Authors
  1. P. C. Morais
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  2. V. K. Garg
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  3. A. C. Oliveira
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  4. L. B. Silveira
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  5. J. G. Santos
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  6. M. M. A. Rodrigues
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  7. A. C. Tedesco
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Corresponding author

Correspondence to P. C. Morais .

Editor information

Editors and Affiliations

  1. Eötvös Loránd University, Budapest, Hungary

    E. Kuzmann

  2. Hungarian Academy of Sciences, Budapest, Hungary

    E. Kuzmann  & K. Lázár  & 

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Morais, P.C. et al. (2009). Nanoscaled biocompatible magnetic drug-delivery system: preparation and characterization. In: Kuzmann, E., Lázár, K. (eds) ISIAME 2008. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01370-6_34

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