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Geometric Morphometrics and the Study of Development

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Advanced Imaging in Biology and Medicine

Abstract

Even though developmental biology seeks to provide developmental explanations for morphological variation, the quantification of morphological variation has been regarded as peripheral to the mechanistic study of development. In this chapter, we argue that this is now changing because the rapidly advancing knowledge of development in post-genomic biology is creating a need for more refined measurements of the morphological changes produced by genetic perturbations or treatments. This need, in turn, is driving the development of new morphometric methods that allow the rapid and meaningful integration of molecular, cellular and morphometric data. We predict that such integration will offer new ways of looking at development, which will lead to significant advances in the study of dysmorphology and also the relationship between the generation of variation through development and its transformation through evolutionary history.

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Author information

Authors and Affiliations

  1. Department of Cell Biology and Anatomy and the McCaig Bone and Joint Institute, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Benedikt Hallgrímsson, Julia C. Boughner & Cairine Logan

  2. Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada

    Andrei Turinsky

  3. Biological Anthropology Graduate Program and the McCaig Bone and Joint Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Trish E. Parsons

  4. Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Sun Center of Excellence for Visual Genomics, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Christoph W. Sensen

Authors
  1. Benedikt Hallgrímsson
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  2. Julia C. Boughner
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  3. Andrei Turinsky
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  4. Trish E. Parsons
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  5. Cairine Logan
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  6. Christoph W. Sensen
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Corresponding authors

Correspondence to Benedikt Hallgrímsson , Andrei Turinsky or Christoph W. Sensen .

Editor information

Editors and Affiliations

  1. Sun Center of Excellence for Visual Genomics Department of Biochemistry and Molecular Biology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Christoph W. Sensen

  2. Department of Cell Biology and Anatomy, G503 Health Sciences Ctr., University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Benedikt Hallgrímsson

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© 2009 Springer-Verlag Berlin Heidelberg

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Hallgrímsson, B., Boughner, J.C., Turinsky, A., Parsons, T.E., Logan, C., Sensen, C.W. (2009). Geometric Morphometrics and the Study of Development. In: Sensen, C.W., Hallgrímsson, B. (eds) Advanced Imaging in Biology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68993-5_15

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  • DOI: https://doi.org/10.1007/978-3-540-68993-5_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68992-8

  • Online ISBN: 978-3-540-68993-5

  • eBook Packages: MedicineMedicine (R0)

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