Abstract
Finite element (FE) analysis is a nondestructive simulation tool that can estimate mechanical properties of biomaterials when combined with 3D imaging modalities such as micro-computed tomography. This chapter will review state-of-the-art FE methods that use micro-CT to generate subject-specific models for application to large cohorts of experimental animal studies, and most recently for patient studies. Methods used to automatically generate FE meshes, and recent developments that improve the accuracy of these meshes, as well as advances in the acquisition of material properties for FE modeling and the incorporation of constitutive material properties into models will be discussed. The application of this technology for in vivo micro-CT is particularly exciting because it provides a method to noninvasively estimate strength, and this can provide valuable information for monitoring disease progress and treatment efficacy. The field is still in the early stages, and there are significant opportunities to advance this unique combination of imaging and modeling technologies to provide new insights into strength-related issues.
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Boyd, S.K. (2009). Image-Based Finite Element Analysis. In: Sensen, C.W., HallgrÃmsson, B. (eds) Advanced Imaging in Biology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68993-5_14
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DOI: https://doi.org/10.1007/978-3-540-68993-5_14
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