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Micro-Computed Tomography

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Advanced Imaging in Biology and Medicine

Abstract

Micro-computed tomography (micro-CT) provides high-resolution three-dimensional (3D) geometry and density information for the analysis of biological materials, and is particularly well-suited for bone research. These detailed 3D data have provided significant insights into issues surrounding bone quality, and the recent advancement of this technology now provides the opportunity to perform these measurements in living subjects, including both experimental animal models and direct patient measurements. This chapter reviews the fundamental principles of micro-CT and caveats related to its use. It describes the current approaches for analyzing these rich 3D datasets, as well as leading-edge developments. These include analysis techniques such as structure classification, image registration, image-guided failure analysis, extrapolation of structure from time series, and high-throughput approaches for morphological analysis.

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Author information

Authors and Affiliations

  1. Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive, Calgary, NW, Alberta, T2N 1N4, Canada

    Steven K. Boyd

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  1. Steven K. Boyd
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Editor information

Editors and Affiliations

  1. Sun Center of Excellence for Visual Genomics Department of Biochemistry and Molecular Biology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Christoph W. Sensen

  2. Department of Cell Biology and Anatomy, G503 Health Sciences Ctr., University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Benedikt Hallgrímsson

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© 2009 Springer-Verlag Berlin Heidelberg

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Boyd, S.K. (2009). Micro-Computed Tomography. In: Sensen, C.W., Hallgrímsson, B. (eds) Advanced Imaging in Biology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68993-5_1

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  • DOI: https://doi.org/10.1007/978-3-540-68993-5_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68992-8

  • Online ISBN: 978-3-540-68993-5

  • eBook Packages: MedicineMedicine (R0)

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