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Central Nervous System Tumors

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Cancer in Adolescents and Young Adults

Part of the book series: Pediatric Oncology ((PEDIATRICO))

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References

  1. Bleyer A, O’Leary M, Barr R, Ries LAG (eds) (2006) Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975–2000. National Cancer Institute, NIH Pub. No. 06-5767, Bethesda, MD

    Google Scholar 

  2. Capra M, Hargrave D, Bartels U, et al (2003) Central nervous system tumours in adolescents. Eur J Cancer 39:2643–2650

    PubMed  CAS  Google Scholar 

  3. IARC (2003) Cancer in Africa: epidemiology and prevention. IARC Press, Lyon, France

    Google Scholar 

  4. Parkin DM, Whelen SL, Ferlay J, et al (2002) Cancer Incidence in Five Continents, Vol. VIII. IARC Press, Lyon, France

    Google Scholar 

  5. Gurney JG, Wall DA, Jukich PJ, Davis FG (1999) The contribution of nonmalignant tumours to CNS tumour incidence rates among children in the United States. Cancer Causes Control 10:101–105

    PubMed  CAS  Google Scholar 

  6. CBTRUS (2004–2005) Statistical report: Primary brain tumours in the United States, 1997–2001. Central Brain Tumour Registry of the United States

    Google Scholar 

  7. Birch JM, Alston RD, Quinn M, Kelsey AM (2003) Incidence of malignant disease by morphological type, in young persons aged 12–24 years in England, 1979–1997. Eur J Cancer 39:2622–2631

    PubMed  CAS  Google Scholar 

  8. Preston-Martin S, Mack WJ (1996) Neoplasms of the nervous system. In: Schottenfield D, Fraumeni JF (eds) Cancer Epidemiology and Prevention. Oxford University Press, New York, pp 1231–1281

    Google Scholar 

  9. Garwicz S, Anderson H, Olsen JH, et al. (2000) Second malignant neoplasms after cancer in childhood and adolescence: a population-based case-control study in the 5 Nordic countries. Int J Cancer 88:672–678

    PubMed  CAS  Google Scholar 

  10. Ron E, Modan B, Boice JD, et al. (1988) Tumours of the brain and nervous system after radiotherapy in childhood. N Eng J Med 319:1033–1039

    CAS  Google Scholar 

  11. Auvinen A, Linet MS, Hatch EE, et al. (2000) Extremely low-frequency magnetic fields and childhood acute lymphoblastic leukemia: an exploratory analysis of alternative exposure metrics. Am J Epidemiol 152:20–31.

    PubMed  CAS  Google Scholar 

  12. Hatch EE, Kleinerman RA, Linet MS, et al. (2000) Do confounding or selection factors of residential wiring codes and magnetic fields distort findings of electromagnetic fields studies. Epidemiology 11:189–98.

    PubMed  CAS  Google Scholar 

  13. Kheifets LI (2001) Electric and magnetic field exposure and brain cancer: a review. Bioelectromagnetics Suppl 5:S120–S131

    Google Scholar 

  14. Kleinerman RA, Kaune WT, Hatch EE, et al. (2000) Are children living near high-voltage power lines at increased risk of acute lymphoblastic leukemia? Am J Epidemiol 151:512–515

    PubMed  CAS  Google Scholar 

  15. Little J (1999) Epidemiology of Childhood Cancer. IARC Press, Lyon, France

    Google Scholar 

  16. Elwood JM (2003) Epidemiological studies of radio frequency exposures and human cancer. Bioelectromagnetics Suppl 6:S63–S73

    Google Scholar 

  17. Huncharek M, Kupelnick B (2004) A meta-analysis of maternal cured meat consumption during pregnancy and the risk of childhood brain tumours. Neuroepidemiology 23:78–84

    PubMed  Google Scholar 

  18. Blot WJ, Henderson BE, Boice JD (1999) Childhood cancer in relation to cured meat intake: review of the epidemiological evidence. Nutr Cancer 34:111–118

    PubMed  CAS  Google Scholar 

  19. Huncharek M, Kupelnick B, Wheeler L (2003) Dietary cured meat and the risk of adult glioma: a meta-analysis of nine observational studies. J Environ Pathol Toxicol Oncol 22:129–137

    PubMed  CAS  Google Scholar 

  20. Boffetta P, Trédaniel J, Greco A (2000) Risk of childhood cancer and adult lung cancer after childhood exposure to passive smoking: a meta-analysis. Environ Health Perspect 108:73–82

    PubMed  CAS  Google Scholar 

  21. Huncharek M, Kupelnick B, Klassen H (2002) Maternal smoking during pregnancy and the risk of childhood brain tumours: a meta-analysis of 6566 subjects from twelve epidemiological studies. J Neurooncol 57:51–57

    PubMed  Google Scholar 

  22. Zahm SH, Ward MH (1998) Pesticides and childhood cancer. Environ Health Perspect 106:893–908

    PubMed  Google Scholar 

  23. Yeni-Komshian H, Holly EA (2000) Childhood brain tumours and exposure to animals and farm life: a review. Paediatr Perinat Epidemiol 14:248–256

    PubMed  CAS  Google Scholar 

  24. Ménégoz F, Little J, Colonna M, et al. (2002) Contacts with animals and humans as risk factors for adult brain tumours. An international case-control study. Eur J Cancer 38:696–704

    PubMed  Google Scholar 

  25. Colt JS, Blair A (1998) Parental occupational exposures and risk of childhood cancer. Environ Health Perspect 106:909–925

    PubMed  Google Scholar 

  26. Cordier S, Monfort C, Filippini G, et al. (2004) Parental exposure to polycyclic aromatic hydrocarbons and the risk of childhood brain tumours: the SEARCH International Childhood Brain Tumour Study. Am J Epidemiol 159:1109–1116

    PubMed  CAS  Google Scholar 

  27. Cordier S, Mandereau L, Preston-Martin S, et al. (2001) Parental occupations and childhood brain tumours: results of an international case-control study. Cancer Causes Control 12:865–874

    PubMed  CAS  Google Scholar 

  28. Carozza SE, Wrensch M, Miike R, et al. (2000) Occupation and adult gliomas. Am J Epidemiol 152:838–846

    PubMed  CAS  Google Scholar 

  29. Cocco P, Dosemeci M, Heineman EF (1998) Occupational risk factors for cancer of the central nervous system: a case-control study on death certificates from 24 U.S. states. Am J Ind Med 33:247–255

    PubMed  CAS  Google Scholar 

  30. De Roos AJ, Stewart PA, Linet MS, et al. (2003) Occupation and the risk of adult glioma in the United States. Cancer Causes Control 14:139–150

    PubMed  Google Scholar 

  31. Navas-Acién A, Pollán M, Gustavsson P, Plato N (2002) Occupation, exposure to chemicals and risk of gliomas and meningiomas in Sweden. Am J Ind Med 42:214–227

    PubMed  Google Scholar 

  32. Brenner AV, Linet MS, Fine HA, et al. (2002) History of allergies and autoimmune disease and risk of brain tumours in adults. Int J Cancer 99:252–259

    PubMed  CAS  Google Scholar 

  33. Schlehofer B, Blettner M, Preston-Martin S, et al. (1999) Role of medical history in brain tumour development. Results from the international adult brain tumour study. Int J Cancer 82:155–160

    PubMed  CAS  Google Scholar 

  34. Wiemels JL, Wiencke JK, Sison JD, et al (2002) History of allergies among adults with glioma and controls. Int J Cancer 98:609–615

    PubMed  CAS  Google Scholar 

  35. Wrensch M, Lee M, Miike R, et al (1997) Familial and personal medical history of cancer and nervous system conditions among adults with glioma and controls. Am J Epidemiol 145:581–593

    PubMed  CAS  Google Scholar 

  36. Schwartzbaum J, Jonsson F, Ahlbom A, et al. (2003) Cohort studies of association between self-reported allergic conditions, immune-related diagnoses and glioma and meningioma risk. Int J Cancer 106:423–428

    PubMed  CAS  Google Scholar 

  37. Wrensch M, Weinberg A, Wiencke J, et al (2001) Prevalence of antibodies to four herpes viruses among adults with glioma and controls. Am J Epidemiol 154:161–165

    PubMed  CAS  Google Scholar 

  38. Wrensch M, Weinberg A, Wiencke J, et al. (2005) History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpes viruses among adults with glioma and controls. Am J Epidemiol 161:929–938

    PubMed  Google Scholar 

  39. Franceschi S, Dal Maso L, La Vecchia C (1999) Advances in the epidemiology of HIV-associated non-Hodgkin lymphoma and other lymphoid neoplasms. Int J Cancer 83:481–485

    PubMed  CAS  Google Scholar 

  40. Dal Maso L, Rezza G, Zambon P, et al., for the Cancer and Aids Registry linkage (2001) Non-Hodgkin lymphoma among young adults with and without AIDS in Italy. Int J Cancer 93:430–435

    Google Scholar 

  41. International Collaboration on HIV and Cancer (2000) Highly active antiretroviral therapy and incidence of cancer in human immunodeficiency virus-infected adults. J Natl Cancer Inst 92:1823–1830

    Google Scholar 

  42. Vilchez RA, Kozinetz CA, Arrington AS, et al (2003) Simian Virus 40 in human cancers. Am J Med 114:675–684

    PubMed  Google Scholar 

  43. Engels EA, Sarkar C, Daniel RW, et al. (2002) Absence of Simian virus 40 in human brain tumours from Northern India. Int J Cancer 101:348–352

    PubMed  CAS  Google Scholar 

  44. Engels EA, Katki HA, Nielsen NM, et al. (2003) Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40. J Natl Cancer Inst 95:532–539

    PubMed  CAS  Google Scholar 

  45. Sivak-Sears NR, Schwartzbaum JA, Miike R, et al (2004) Case-control study of use of nonsteroidal antiinflammatory drugs and glioblastoma multiforme. Am J Epidemiol 159:1131–1139

    PubMed  Google Scholar 

  46. Friis S, Sorensen HT, McLaughlin JK, et al (2003) A population-based cohort study of the risk of colorectal and other cancers among users of low-dose aspirin. Br J Cancer 88:684–688

    PubMed  CAS  Google Scholar 

  47. Gurney JG, Mueller BA, Preston-Martin S, et al. (1997) A study of pediatric brain tumours and their association with epilepsy and anticonvulsant use. Neuroepidemiology 16:248–255

    PubMed  CAS  Google Scholar 

  48. Inskip PD, Mellemkjaer L, Gridley G, Olsen JH (1998) Incidence of intracranial tumours following hospitalization for head injuries (Denmark). Cancer Causes Control 9:109–116

    PubMed  CAS  Google Scholar 

  49. Wrensch M, Miike R, Lee M, Neuhaus J (2000) Are prior head injuries or diagnostic x-rays associated with glioma in adults? The effects of control selection bias. Neuroepidemiology 19:234–244

    PubMed  CAS  Google Scholar 

  50. Preston-Martin S, Pogoda JM, Schlehofer B, et al. (1998) An international case-control study of adult glioma and meningioma: the role of head trauma. Int J Epidemiol 27:579–586

    PubMed  CAS  Google Scholar 

  51. Friedman J, Birch P (1997) An association between optic glioma and other tumours of the central nervous system in neurofibromatosis type 1. Neuropediatrics 28:131–132

    PubMed  CAS  Google Scholar 

  52. Gutmann DH, Rasmussen SA, Wolkenstein P, et al. (2002) Gliomas presenting after age 10 in individuals with neurofibromatosis type 1 (NF1). Neurology 59:759–761

    PubMed  CAS  Google Scholar 

  53. Listernick R, Charrow J, Greenwald MJ, Easterly NB (1989) Optic gliomas in children with neurofibromatosis type 1. J Pediatr 114:788–792

    PubMed  CAS  Google Scholar 

  54. Molloy PT, Bilaniuk LT, Vaughan SN, et al. (1995) Brainstem tumours in patients with neurofibromatosis type 1: a distinct clinical entity. Neurology 45:1897–1902

    PubMed  CAS  Google Scholar 

  55. Riffaud L, Vinchon M, Ragragui O, et al (2002) Hemispheric cerebral gliomas in children with NF1: arguments for a long term follow up. Childs Nerv Syst 18:43–47

    PubMed  Google Scholar 

  56. Evans DGR, Sainio M, Baser ME (2000) Neurofibromatosis type 2. J Med Genet 37:897–904

    PubMed  CAS  Google Scholar 

  57. Maddock IR, Moran A, Maher ER, T et al. (1996) A genetic register for von Hippel-Lindau disease. J Med Genet 33:120–127

    PubMed  CAS  Google Scholar 

  58. Roach ES, Smith M, Huttenlocher P, et al (1992) Diagnostic criteria: tuberous sclerosis complex. Report of the Diagnostic Criteria Committee of the National Tuberous Sclerosis Association. J Child Neurol 7:221–224

    PubMed  CAS  Google Scholar 

  59. Webb D, Fryer AE, Osborne JP (1996) Morbidity associated with tuberous sclerosis: a population study. Dev Med Child Neurol 38:146–155

    PubMed  CAS  Google Scholar 

  60. Corradetti M, Inoki K, Bardeesy N, et al (2004) Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome. Genes Dev 18:1533–1538

    PubMed  CAS  Google Scholar 

  61. Inoki K, Zhu T, Guan KL (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577–590

    PubMed  CAS  Google Scholar 

  62. Kleihues P, Schäuble B, Hausen AZ, et al(1997) Tumours associated with p53 germline mutations. A synopsis of 91 families. Am J Pathol 150:1–13

    PubMed  CAS  Google Scholar 

  63. Birch JM, Hartley AL, Blair V, et al. (1990) Cancer in the families of children with soft tissue sarcoma. Cancer 66:2239–2248

    PubMed  CAS  Google Scholar 

  64. Garber JE, Goldstein AM, Kantor AF, et al (1991) Follow-up study of twenty-four families with Li-Fraumeni syndrome. Cancer Res 51:6094–6097

    PubMed  CAS  Google Scholar 

  65. Li FP, Fraumeni JF Jr, Mulvihill JJ, et al. (1988) A cancer family syndrome in 24 kindreds. Cancer Res 48:5358–5362

    PubMed  CAS  Google Scholar 

  66. Varley JM (2003) Germline TP53 mutations and Li-Fraumeni syndrome. Hum Mutat 21:313–320

    PubMed  CAS  Google Scholar 

  67. Birch JM, Alston RD, McNally RJQ, et al. (2001) Relative frequency and morphology of cancers in carriers of germline TP53 mutations. Oncogene 20:4621–4628

    PubMed  CAS  Google Scholar 

  68. Trump D, Farren B, Wooding C, et al. (1996) Clinical studies of multiple endocrine neoplasia type 1 (MEN1). Q J Med 89:653–669

    CAS  Google Scholar 

  69. Robinson S, Cohen A (2000) Cowden disease and L’Hermitte-Duclos disease: characterization of a new phakomatosis. Neurosurgery 46:371

    PubMed  CAS  Google Scholar 

  70. Kleihues P, Cavenee WK (eds) (2000) Tumours of the Nervous System. World Health Organization Classification of Tumours. Oxford University Press, Lyon, France

    Google Scholar 

  71. Paraf F, Jothy S, Van Meir EG (1997) Brain tumour-polyposis syndrome: two genetic diseases? J Clin Oncol 15:2744–2758

    PubMed  CAS  Google Scholar 

  72. Aarnio M, Sankila R, Pukkala E, et al. (1999) Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 81:214–218

    PubMed  CAS  Google Scholar 

  73. Vasen HFA, Sanders EACM, Taal BG, et al. (1996) The risk of brain tumours in hereditary non-polyposis colorectal cancer (HNPCC). Int J Cancer 65:422–425

    PubMed  CAS  Google Scholar 

  74. Hamilton SR, Liu B, Parsons RE, et al. (1995) The molecular basis of Turcot’s syndrome. N Eng J Med 332:839–847

    CAS  Google Scholar 

  75. Hasle H (2001) Pattern of malignant disorders in individuals with Down’s syndrome. Lancet Oncol 2:429–436

    PubMed  CAS  Google Scholar 

  76. Amlashi SFA, Riffaud L, Brassier G, Morandi X (2003) Nevoid basal cell carcinoma syndrome: relation with desmoplastic medulloblastoma in infancy. A population-based study and review of the literature. Cancer 98:618–624

    PubMed  Google Scholar 

  77. Biegel JA, Zhou J-Y, Rorke LB, et al (1999) Germ-line and acquired mutations of IN11 in atypical teratoid and rhabdoid tumours. Cancer Res 59:74–79

    PubMed  CAS  Google Scholar 

  78. Cowan R, Hoban P, Kelsey A, et al (1997) The gene for the naevoid basal cell carcinoma syndrome acts as a tumour-suppressor gene in medulloblastoma. Br J Cancer 76:141–145

    PubMed  CAS  Google Scholar 

  79. Stiller C, Bleyer W (2004) Epidemiology. In: Walker D, Perilongo G, Punt J, Taylor R (eds) Brain and Spinal Tumours of Childhood. Arnold, London, pp 35–49

    Google Scholar 

  80. Becker Y (1986). Cancer in ataxia-telangiectasia patients: analysis of factors leading to radiation-induced and spontaneous tumours. Anticancer Res 6:1021–1032

    PubMed  CAS  Google Scholar 

  81. Chun HH, Gatti RA (2004) Ataxia-telangiectasia, an evolving phenotype. DNA Repair 3:1187–1196

    PubMed  CAS  Google Scholar 

  82. Khanna (2000) Cancer risk and the ATM gene: a continuing debate. J Natl Cancer Inst 92:795–802

    PubMed  CAS  Google Scholar 

  83. Kuhne M, Riballo E, Rief N, et al (2004) A doublestrand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 64:500–508

    PubMed  Google Scholar 

  84. Hemminki K, Li X (2004) Association of brain tumours with other neoplasms in families. Eur J Cancer 40:253–259

    PubMed  CAS  Google Scholar 

  85. Malmer B, Henriksson, Gronberg H (2002) Different aetiology of familial low-grade and high-grade glioma? A nationwide cohort study of familial glioma. Neuroepidemiology 21:279–286

    PubMed  Google Scholar 

  86. Malmer B, Henriksson R, Grönberg H ((2003) Familial brain tumours — genetics of environment? A nationwide cohort study of cancer risk in spouses and firstdegree relatives of brain tumour patients. Int J Cancer 1106:260–263

    PubMed  CAS  Google Scholar 

  87. Hemminki K, Li X, Collins VP (2001) A populationbased study of familial central nervous system hemangioblastomas. Neuroepidemiology 20:257–261

    PubMed  CAS  Google Scholar 

  88. Paunu N, Syrjäkoski K, Sankila R, et al. (2001)Analysis of p53 tumour suppressor gene in families with multiple glioma patients. J Neurooncol 55:159–165

    PubMed  CAS  Google Scholar 

  89. Nicholson JC, Punt J, Hale J, et al; Germ Cell Tumour Working Groups of the United Kingdom Children’s Cancer Study Group (UKCCSG) and International Society of Paediatric Oncology (SIOP) (2002) Neurosurgical management of paediatric germ cell tumours of the central nervous system — a multi-disciplinary team approach for the new millennium. Br J Neurosurg 16:93–95

    PubMed  CAS  Google Scholar 

  90. Walker DA, Punt JA, Sokal M (1999) Clinical management of brain stem glioma. Arch Dis Child 80:558–564

    PubMed  CAS  Google Scholar 

  91. Walker DA, Punt JAG, Sokal M (2004) Brainstem tumours. In: Walker D, Perilongo G, Punt J Taylor R (eds) Brain and Spinal Tumours of Childhood. Arnold, London, pp 291–313

    Google Scholar 

  92. Westphal M, Hilt DC, Bortey E, et al. (2003) A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro-oncology 5:79–88

    PubMed  CAS  Google Scholar 

  93. Barnett FH, Scharer-Schuksz M, Wood M, et al (2004) Intra-arterial delivery of endostatin gene to brain tumours prolongs survival and alters tumour vessel ultrastructure. Gene Ther 11:1283–1289

    PubMed  CAS  Google Scholar 

  94. Chiocca EA, Abbed KM, Tatter S, et al. (2004) A phase 1 open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoural region of recurrent malignant gliomas in the adjuvant setting. Mol Ther 10:958–966

    PubMed  CAS  Google Scholar 

  95. Glorioso JC, Fink DJ (2004) Herpes vector-mediated gene transfer in treatment of diseases of the nervous system. Annu Rev Microbiol 58:253–271

    PubMed  CAS  Google Scholar 

  96. Immonen A, Vapalahti M, Tyynela K, et al. (2004) Adv-HSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised controlled study. Mol Ther 10:967–972

    PubMed  CAS  Google Scholar 

  97. McKeown SR, Ward C, Robson T (2004). Gene-directed enzyme prodrug therapy: a current assessment. Curr Opin Mol Ther 6:421–435

    PubMed  CAS  Google Scholar 

  98. Okada H, Pollack IF (2004) Cytokine gene therapy for malignant glioma. Expert Opin Biol Ther 4:1609–1620

    PubMed  CAS  Google Scholar 

  99. Gnekow A, Packer R, Kortmann R (2004) Astrocytic tumours, low-grade: treatment considerations by primary site and tumour dissemination. In: Walker D, Perilongo G, Punt J, Taylor R (eds) Brain and Spinal Tumours of Childhood. Arnold, London, pp 259–276

    Google Scholar 

  100. Klein M, Heimans JJ, Aaronson NK, et al. (2002) Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low grade gliomas: a comparative study. Lancet 360:1361–1368

    PubMed  CAS  Google Scholar 

  101. Balis FM, Poplack DG (1993) Cancer Chemotherapy. In: Nathan DG, Oski FA (eds) Hematology of Infancy and Childhood. WB Saunders, Philadelphia, pp 1207–1238

    Google Scholar 

  102. Tabori U, Sung L, Hukin J, et al. (2005) Medulloblastoma in the second decade of life: a specific group with respect to toxicity and management. A Canadian Pediatric Brain Tumor Consortium Study. Cancer 103:1874–1880

    PubMed  Google Scholar 

  103. Glaser AW, Buxton N, Hewitt M, et al (1996) The role of steroids in paediatric central nervous system malignancies. Br J Neurosurg 10:123–124

    Google Scholar 

  104. Weissman DE (1988) Glucocorticoid treatment for brain metastases and epidural spinal cord compression: a review. J Clin Oncol 6:543–551

    PubMed  CAS  Google Scholar 

  105. Motoyama T, Watanabe H, Yamamoto T, Sekiguchi M (1987) Production of alpha-fetoprotein by human germ cell tumours in vivo and in vitro. Acta Pathol Jpn 37:1263–1277

    PubMed  CAS  Google Scholar 

  106. Motoyama T, Watanabe H, Yamamoto T, Sekiguchi M (1988) Production of beta-human chorionic gonadotropin by germ cell tumours in vivo and in vitro. Acta Pathol Jpn 38:577–590

    PubMed  CAS  Google Scholar 

  107. Packer RJ, Sutton LN, Rosenstock JG, et al. (1984) Pineal region tumours of childhood. Pediatrics 74:97–102

    PubMed  CAS  Google Scholar 

  108. Itoyama Y, Kochi M, Yamamoto H, et al (1990) Clinical study of intracranial nongerminomatous germ cell tumours producing alpha-fetoprotein. Neurosurgery 27:454–460

    PubMed  CAS  Google Scholar 

  109. Kida Y, Kobayashi T, Yoshida J, et al (1986) Chemotherapy with cisplatin for αFP-secreting germ-cell tumours of the central nervous system. J Neurosurg 65:470–475

    PubMed  CAS  Google Scholar 

  110. Wara WM, Jenkin RD, Evans A, et al. (1979) Tumours of the pineal and suprasellar region: Children’s Cancer Study Group treatment results 1960–1975: a report from Children’s Cancer Study Group. Cancer 43:698–701

    PubMed  CAS  Google Scholar 

  111. Jennings MT, Gelman R, Hochberg F (1985) Intracranial germ-cell tumours: natural history and pathogenesis. J Neurosurg 63:155–167

    PubMed  CAS  Google Scholar 

  112. Einhorn LH, Williams SD (1980) Chemotherapy of disseminated testicular cancer. A random prospective study. Cancer 46:1339–1344

    PubMed  CAS  Google Scholar 

  113. Williams SD, Stablein DM, Einhorn LH, et al. (1987) Immediate adjuvant chemotherapy versus observation with treatment at relapse in pathological stage II testicular cancer. N Engl J Med 317:1433–1438

    PubMed  CAS  Google Scholar 

  114. Kirshner JJ, Ginsberg SJ, Fitzpatrick AV, Comis RL (1981) Treatment of a primary intracranial germ cell tumour with systemic chemotherapy. Med Pediatr Oncol 9:361–365

    PubMed  CAS  Google Scholar 

  115. Itoyama Y, Kochi M, Kuratsu J, et al. (1995) Treatment of intracranial non-germinomatous malignant germ cell tumours producing (alpha)-fetoprotein. Neurosurgery 36:459–466

    PubMed  CAS  Google Scholar 

  116. Kobayashi T, Yoshida J, Ishiyama J, et al (1989) Combination chemotherapy with cisplatin and etoposide for malignant intracranial germ-cell tumours. An experimental and clinical study. J Neurosurg 70:676–681

    PubMed  CAS  Google Scholar 

  117. Allen JC, DaRosso RC, Donahue B, Nirenberg A (1994) A phase II trial of pre-irradiation carboplatin in newly diagnosed germinoma of the central nervous system. Cancer 74:940–944

    PubMed  CAS  Google Scholar 

  118. Allen JC, Kim JH, Packer RJ (1987) Neoadjuvant chemotherapy for newly diagnosed germ-cell tumours of the central nervous system. J Neurosurg 67:65–70

    PubMed  CAS  Google Scholar 

  119. Shibamoto Y, Abe M, Yamashita J, et al. (1988) Treatment results of intracranial germinoma as a function of the irradiated volume. Int J Radiat Oncol Biol Phys 15:285–290

    PubMed  CAS  Google Scholar 

  120. Ogawa K, Shikama N, Toita T, et al. (2004) Long-term results of radiotherapy for intracranial germinoma: a multi-institutional retrospective review of 126 patients. Int J Radiat Oncol Biol Phys 58:705–713

    PubMed  Google Scholar 

  121. Aoyama H, Shirato H, Kakuto Y, et al. (1998) Pathologically-proven intracranial germinoma treated with radiation therapy. Radiother Oncol 47:201–205. Erratum in: Radiother Oncol 1999, 50:241

    PubMed  CAS  Google Scholar 

  122. Shirato H, Nishio M, Sawamura Y, et al. (1997) Analysis of long-term treatment of intracranial germinoma. Int J Radiat Oncol Biol Phys 37:511–515

    PubMed  CAS  Google Scholar 

  123. Ogawa K, Toita T, Nakamura K, et al. (2003) Treatment and prognosis of patients with intracranial nongerminomatous malignant germ cell tumours: a multiinstitutional retrospective analysis of 41 patients. Cancer 98:369–376

    PubMed  Google Scholar 

  124. Kiltie AE, Gattamaneni HR (1995) Survival and quality of life of paediatric intracranial germ cell tumour patients treated at the Christie Hospital, 1972–1993. Med Pediatr Oncol 25:450–456

    PubMed  CAS  Google Scholar 

  125. Aoyama H, Shirato H, Ikeda J, et al (2002) Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumours. J Clin Oncol 20:857–865

    PubMed  CAS  Google Scholar 

  126. Balmaceda C, Heller G, Rosenblum M, et al. (1996) Chemotherapy without irradiation — a novel approach for newly diagnosed CNS germ cell tumours: results of an international co-operative trial. The First International Central Nervous System Germ Cell Tumour Study. J Clin Oncol 14:2908–2915

    PubMed  CAS  Google Scholar 

  127. Bamberg M, Kortmann RD, Calaminus G, et al. (1999) Radiation therapy for intracranial germinoma: results of the German Co-operative Prospective Trials MAKEI 83/86/89. J Clin Oncol 17:2585–2592

    PubMed  CAS  Google Scholar 

  128. Baranzelli MC, Patte C, Boufet E, et al. (1997) Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology. Cancer 80:1792–1797

    PubMed  CAS  Google Scholar 

  129. Bouffet E, Baranzelli MC, et al. (1999) Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience. Societe Francaise d’Oncologie Pediatrique. Br J Cancer 79:1199–1204

    PubMed  CAS  Google Scholar 

  130. Calaminus G, Bamberg M, Baranzelli MC, et al. (1994). Intracranial germ cell tumours: a comprehensive update of the European data. Neuropediatrics 25:26–32

    PubMed  CAS  Google Scholar 

  131. Chang TK, Wong TT, Hwang B (1995) Combination chemotherapy with vinblastine, bleomycin, cisplatin, and etoposide (VBPE) in children with intracranial germ cell tumours. Med Pediatr Oncol 24:368–372

    PubMed  CAS  Google Scholar 

  132. Herrman HD, Westphal M, Winkler K, et al (1994) Treatment of non-germinomatous germ-cell tumours of the pineal region. Neurosurgery 34:524–529

    Google Scholar 

  133. Eiser C (1997) Children’s quality of life measures. Arch Dis Child 77:350–354

    PubMed  CAS  Google Scholar 

  134. Glaser AW, Furlong W, Walker DA, et al. (1999) Applicability of the Health Utilities Index to a population of childhood survivors of central nervous system tumours in the United Kingdom. Eur J Cancer 35:256–261

    PubMed  CAS  Google Scholar 

  135. Merchant TE, Davis BJ, Sheldon JM, Leibel SA (1998) Radiation therapy for relapsed CNS germinoma after primary chemotherapy. J Clin Oncol 16:204–209

    PubMed  CAS  Google Scholar 

  136. Kennedy C, Bull K (2004) Effect of neo-adjuvant chemotherapy on long-term health state and behaviour in the PNET3 RCT of treatment for primitive neuro-ectodermal tumour (PNET). ISPNO, Boston (abstract)

    Google Scholar 

  137. Benesch M, Lackner H, Schagerl S, et al (2001) Tumour-and treatment-related side effects after multimodal therapy of childhood intracranial germ cell tumours. Acta Paediatr 90:264–270

    PubMed  CAS  Google Scholar 

  138. Sankaranarayanan R, Black RJ, Swaminathan R, Parkin DM (1998) An overview of cancer survival in developing countries. IARC Sci Publ 145:135–173

    PubMed  Google Scholar 

  139. Jenkin D, Shabanah MA, Shail EA, et al. (2000) Prognostic factors for medulloblastoma. Int J Radiat Oncol Biol Phys 47:573–584

    PubMed  CAS  Google Scholar 

  140. Liu Y, Zhu Y, Gao L, et al. (2005) Radiation treatment for medulloblastoma: a review of 64 cases at a single institute. Jpn J Clin Oncol 35:111–115

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Medical School of Nottingham QMC, Nottingham, NG72UH, UK

    David A. Walker M.B. B.S.

  2. Department of Hematology/Oncology, Children’s Hospital and Clinics of Minnesota, 2525 Chicago Ave. S, MS 32-4150, Minneapolis, MN, 55404, USA

    Anne Bendel M.D.

  3. Childhood Cancer Research Group, University of Oxford, Woodtsock Road, Oxford, OX2 6HJ, UK

    Charles Stiller Ph.D.

  4. Queen’s Medical Centre, University Hospital, NHS Trust, Derby Road, Nottingham, NG7 2UH, UK

    Paul Byrne

  5. Nottingham Children’s Brain Tumour Research Centre, Nottingham City Hospital, Nottingham, NG7 24H, UK

    Michael Soka

Authors
  1. David A. Walker M.B. B.S.
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  2. Anne Bendel M.D.
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  3. Charles Stiller Ph.D.
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  4. Paul Byrne
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  5. Michael Soka
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Editor information

Editors and Affiliations

  1. St. Charles Medical Center, Bend, Oregon, USA

    W. Archie Bleyer

  2. McMaster University, Hamilton, Ontario, Canada

    Ronald D. Barr

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© 2007 Springer-Verlag Berlin Heidelberg

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Walker, D.A., Bendel, A., Stiller, C., Byrne, P., Soka, M. (2007). Central Nervous System Tumors. In: Bleyer, W.A., Barr, R.D. (eds) Cancer in Adolescents and Young Adults. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68152-6_10

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  • DOI: https://doi.org/10.1007/978-3-540-68152-6_10

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  • Online ISBN: 978-3-540-68152-6

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