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Applications of Synchrotron Radiation pp 151–191Cite as

Investigation of Neurodegenerative Disorders (II)

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Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

In the previous chapter, we introduced the important role played by transition metal elements in many neurodegenerative disorders and concentrated on the case of Guamanian parkinsonism-dementia complex (PDC). Synchrotron radiation-based micro-XRF and XANES analyses are ideal techniques for providing the distributions, concentrations and chemical states of trace elements. Furthermore, their non-destructiveness allows histological analysis of the samples after the elemental analysis. These features cannot be obtained by conventional techniques and represent a new approach to biomedical studies by providing quantitative information which may be of great significance in elucidating the role of intracellular trace elements. In this chapter we extend the application of SR to cases of amyotrophic lateral sclerosis (ALS), Alzheimer’s disease and Friedreich Ataxia.

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References

  1. L.P. Rowland, N.A. Shneider, N. Engl. J. Med., 2001, 344, 1688.

    Article  Google Scholar 

  2. Y. Kokubo, S. Kuzuhara, Y. Narita, K. Kikugawa, R. Nakano, T. Inuzuka, S. Tsuji, M. Watanabe, T. Miyazaki, S. Murayama, Y. Ihara, ARch. Neurol., 1999, 56, 1506.

    Article  Google Scholar 

  3. I. Fridovich, Advances in Enzymology and related areas of molecular biology, 1986, 58, 61.

    Article  Google Scholar 

  4. D.W. Cleveland, J. Liu, Nature Med., 2000, 6, 1320.

    Article  Google Scholar 

  5. D.R. Rosen, T. Siddique, D. Patterson, D.A. Figlewicz, P. Sapp, A. Hentati, D. Donaldson, J. Goto, J.P. Oregan, H.X. Deng, Z. Rahmani, A. Krizus, D. Mckennayasek, A. Cayabyab, S.M. Gaston, R. Berger, R.E. Tanzi, J.J. Halperin, B. Herzfeldt, R. Vandenbergh, W.Y. Hung, T. Bird, G. Deng, D.W. Mulder, C. Smyth, N.G. Laing, E. Soriano, M.A. Pericakvance, J. Haines, G.A. Rouleau, J.S. Gusella, H.R. Horvitz, R.H. Brown, Nature, 1993, 362, 59.

    Article  ADS  Google Scholar 

  6. W. Robberecht, J. Neurol., 2000, 247, S1.

    Article  Google Scholar 

  7. L.I. Bruijn, M.K. Houseweart, S. Kato, K.L. Anderson, S.D. Anderson, E. Ohama, A.G. Reaume, R.W. Scott, D.W. Cleveland, Science, 1998, 281, 1851.

    Article  ADS  Google Scholar 

  8. M.E. Gurney, H.F. Pu, A.Y. Chiu, M.C. Dalcanto, C.Y. Polchow, D.D. Alexander, J. Caliendo, A. Hentati, Y.W. Kwon, H.X. Deng, W.J. Chen, P. Zhai, R.L. Sufit, T. Siddique, Science, 1994, 264, 1772.

    Article  ADS  Google Scholar 

  9. J.P. Crow, J.B. Sampson, Y.X. Zhuang, J.A. Thompson, J.S. Beckman, J. Neurochem., 1997, 69, 1936.

    Article  Google Scholar 

  10. A.G. Estevez, J.P. Crow, J.B. Sampson, C. Reiter, Y.X. Zhuang, G.J. Richardson, M.M. Tarpey, L. Barbeito, J.S. Beckman, Science, 1999, 286, 2498.

    Article  Google Scholar 

  11. G.A. Rouleau, A.W. Clark, K. Rooke, A. Pramatarova, A. Krizus, O. Suchowersky, J.P. Julien, D. Figlewicz, Ann. Neurol., 1996, 39, 128.

    Article  Google Scholar 

  12. L.M. Murphy, R.W. Strange, S.S. Hasnain, Structure, 1997, 5, 371.

    Article  Google Scholar 

  13. P.J. Hart, H.B. Liu, M. Pellegrini, A.M. Nersissian, E.B. Gralla, J.S. Valentine, D. Eisenberg, Protein Sci., 1998, 7, 545.

    Google Scholar 

  14. H. Takahashi, No to Shinkei, 1972, 47, 292.

    Google Scholar 

  15. S. Kato, H. Hayashi, K. Nakashima, E. Namba, M. Kato, A. Hirano, I. Nakano, K. Asayama, E. Ohama, Am. J. Pathol., 1997, 151, 611.

    Google Scholar 

  16. T. Koide, S. Igarashi, K. Kikugawa, R. Nakano, T. Inuzuka, M. Yamada, H. Takahashi, S. Tsuji, Neurosci. Lett., 1998, 257, 29.

    Article  Google Scholar 

  17. “Molecular Mechanism and Therapeutics of Amyotrophic Lateral Sclerosis”, ed. K Abe, 2001, 41.

    Google Scholar 

  18. P.J. Shaw, V. Forrest, P.G. Ince, J.P. Richardson, H.J. Wastell, Neurodegeneration, 1995, 4, 209.

    Article  Google Scholar 

  19. Y. Ogawa, H. Kosaka, T. Nakanishi, A. Shimizu, N. Ohoi, H. Shouji, T. Yanagihara, S. Sakoda, Biochem. Biophys. Res. Commun., 1997, 241, 251.

    Article  Google Scholar 

  20. A.G. Butt, J.M. Bowler, C.W. McLaughlin, J. Membr. Biol., 1998, 162, 17.

    Article  Google Scholar 

  21. G. Weiss, G. Werner-Felmayer, E.R. Werner, K. Grunewald, H. Wachter, M.W. Hentze, J. Exp. Med., 1994, 180, 969.

    Article  Google Scholar 

  22. P.J. Shaw, R.M. Chinnery, P.G. Ince, Brain Res., 1994, 655, 186.

    Article  Google Scholar 

  23. S.G. Carriedo, H.Z. Yin, J.H. Weiss, J. Neurosci., 1996, 16, 4069.

    Google Scholar 

  24. S. Kwak, R. Nakamura, J. Neurol. Sci., 1995, 129, 99.

    Article  Google Scholar 

  25. Y.M. Lu, H.Z. Yin, J. Chiang, J.H. Weiss, J. Neurosci., 1996, 16, 5457.

    Google Scholar 

  26. S.G. Carriedo, H.Z. Yin, S.L. Sensi, J.H. Weiss, J. Neurosci., 1998, 18, 7727.

    Google Scholar 

  27. S.G. Carriedo, S.L. Sensi, H.Z. Yin, J.H. Weiss, J. Neurosci., 2000, 20, 240.

    Google Scholar 

  28. M. Kondo, R. Sumino, H. Okado, J. Neurosci., 1997, 17, 1570.

    Google Scholar 

  29. M.E. Alexianu, B.K. Ho, A.H. Mohamed, V. La Bella, R.G. Smith, S.H. Appel, Ann. Neurol., 1994, 36, 846.

    Article  Google Scholar 

  30. A. Takahashi, P. Camacho, J.D. Lechleiter, B. Herman, Phys. Rev., 1999, 79, 1089.

    Google Scholar 

  31. J.W. McDonald, T. Bhattacharyya, S.L. Sensi, D. Lobner, H.S. Ying, L.M. Canzoniero, D.W. Choi, J. Neurosci., 1998, 18, 6290.

    Google Scholar 

  32. S.L. Sensi, H.Z. Yin, S.G. Carriedo, S.S. Rao, J.H. Weiss, Neurobiol., 1999, 96, 2414.

    Google Scholar 

  33. D.J. Selkoe, Trends. Neurosci., 1993, 16, 403.

    Article  Google Scholar 

  34. A.I. Bush, W.H. Pettingell, M.D. Paradis, R.E. Tanzi, J. Biol. Chem., 1994, 269, 12152.

    Google Scholar 

  35. C.S. Atwood, R.C. Scarpa, X. Huang, R.D. Moir, W.D. Jones, D.P. Fairlie, R.E. Tanzi, A.I. Bush, J. Neurochem., 2000, 75, 1219.

    Article  Google Scholar 

  36. R.A. Cherny, C.S. Atwood, M.E. Xilinas, D.N. Gray, W.D. Jones, C.A. McLean, K.J. Barnham, I. Volitakis, F.W. Fraser, Y.S. Kim, X. Huang, L.E. Goldstein, R.D. Moir, J.T. Lim, K. Beyreuther, H. Zheng, R.E. Tanzi, C.L. Masters, A.I. Bush, Neuron, 2001, 30, 665.

    Article  Google Scholar 

  37. A.I. Bush, W.H. Pettingell, G. Multhaup, M.D. Paradis, J.P. Vonsattel, J.F. Gusella, K. Beyreuther, C.L. Masters, R.E. Tanzi, Science, 1994, 265, 1464.

    Article  ADS  Google Scholar 

  38. R.A. Cherny, J.T. Legg, C.A. McLean, D.P. Fairlie, X.D. Huang, C.S. Atwood, K. Beyreuther, R.E. Tanzi, C.L. Masters, A.I. Bush, J. Biol. Chem., 1999, 274, 23223.

    Article  Google Scholar 

  39. X.D. Huang, M.P. Cuajungco, C.S. Atwood, M.A. Hartshorn, J.D. Tyndall, G.R. Hanson, K.C. Stokes, M. Leopold, G. Multhaup, L.E. Goldstein, R.C. Scarpa, A.J. Saunders, J. Lim, R.D. Moir, C. Glabe, E.F. Bowden, C.L. Masters, D.P. Fairlie, R.E. Tanzi, A.I. Bush, J. Biol. Chem., 1999, 4, 37111.

    Article  Google Scholar 

  40. X.D. Huang, C.S. Atwood, M.A. Hartshorn, G. Multhaup, L.E. Goldstein, R.C. Scarpa, M.P. Cuajungco, D.N. Gray, J. Lim, R.D. Moir, R.E. Tanzi, A.I. Bush, Biochemistry, 1999, 38, 7609.

    Article  Google Scholar 

  41. A.I. Bush, Curr. Opin. Chem. Biol., 2000, 4, 184.

    Article  Google Scholar 

  42. C.M. Thompson, W.R. Markesbery, W.D. Ehmann, Y.X. Mao, D.E. Vance, Neurotoxicology, 1988, 9, 1.

    Google Scholar 

  43. J.R. Connor, S.L. Menzies, S.M. St. Martin, E.J. Mufson, J. Neurosci. Res., 1992, 31, 75.

    Article  Google Scholar 

  44. M.A. Smith, P.L. Harris, L.M. Sayre, G. Perry, Proc. Natl. Acad. Sci. USA, 1997, 94, 9866.

    Article  ADS  Google Scholar 

  45. M.A. Smith, K. Wehr, P.L. Harris, S.L. Siedlak, J.R. Connor, G. Perry, Brain Res., 1998, 788, 232.

    Article  Google Scholar 

  46. Q. Guo, B.L. Sopher, K. Furukawa, D.G. Pham, N. Robinson, G.M. Martin, M.P. Mattson, J. Neurosci., 1997, 17, 4212.

    Google Scholar 

  47. M.P. Mattson, H.Y. Zhu, J. Yu, M.S. Kindy, J. Neurosci., 2000, 20, 1358.

    Google Scholar 

  48. A. Alves-Rodrigues, L. Gregori, M.E. Figueiredo-Pereira, Trends. Neurosci., 1998, 21, 516.

    Article  Google Scholar 

  49. T. Kudo, K. Iqbal, R. Ravid, D.F. Swaab, I. Grundkeiqbl, Brain Res., 1994, 639, 1.

    Article  Google Scholar 

  50. W.D. Ehmann, W.R. Markesbery, M. Alsuddin, T.I. Hossain, E.H. Brubaker, Neurotoxicology, 1986, 7, 197.

    Google Scholar 

  51. W.R. Markesbery, Free Radical Bio. Med., 1997, 23, 134.

    Article  Google Scholar 

  52. C.C. Curtain, F. Ali, I. Volitakis, R.A. Cherny, R.S. Norton, K. Beyreuther, C.J. Barrow, C.L. Masters, A.I. Bush, K.J. Barnham, J. Biol. Chem., 2001, 276, 20466.

    Article  Google Scholar 

  53. V. Campuzano, L. Montermini, M.D. Molto, L. Pianese, M. Cossee, F. Cavalcanti, E. Monros, F. Rodius, F. Duclos, A. Monticelli, F. Zara, J. Canizares, H. Koutnikova, S.I. Bidichandani, C. Gellera, A. Brice, P. Trouillas, G. DeMichele, A. Filla, R. DeFrutos, F. Palau, P.I. Patel, S. DiDonato, J.L. Mandel, S. Cocozza, M. Koenig, M. Pandolfo, Science, 1996, 271, 1423.

    Article  ADS  Google Scholar 

  54. V. Campuzano, L. Montermini, Y. Lutz, L. Cova, C. Hindelang, S. Jiralerspong, Y. Trottier, S.J. Kish, B. Faucheux, P. Trouillas, F. J. Authier, A. Durr, J.L. Mandel, A. Vescovi, M. Pandolfo, M. Koenig, Hum. Mol. Genet., 1997, 6, 1771.

    Article  Google Scholar 

  55. M. Cossée, V. Campuzano, H. Koutnikova, K. Fischbeck, J.L. Mandel, M. Koenig, S.I. Bidichandani, P.I. Patel, M.D. Molte, J. Canizares, R. De-Frutos, L. Pianese, F. Cavalcanti, A. Monticelli, S. Cocozza, L. Montermini, M. Pandolfo, Nat. Genet., 1997, 15, 337.

    Article  Google Scholar 

  56. M. Babcock, D. De Silva, R. Oaks, S. Davis-Kaplan, S. Jiralerspong, L. Montermini, M. Pandolfo, J. Kaplan, Science, 1997, 276, 1709.

    Article  Google Scholar 

  57. D.C. Radisky, M.C. Babcock, J. Kaplan, J. Biol. Chem., 1999, 274, 4497.

    Article  Google Scholar 

  58. M.B. Delatycki, J. Camakaris, H. Brooks, T. Evans-Whipp, D.R. Thorburn, R. Williamson, S.M. Forrest, Ann. Neurol., 1999, 45, 673.

    Article  Google Scholar 

  59. A. Rötig, P. De Lonlay, D. Chretien, F. Foury, M. Koenig, D. Sidi, A. Munnich, P. Rustin, Nat. Genet., 1997, 17, 215.

    Article  Google Scholar 

  60. M. Pandolfo, Arch. Neurol., 1999, 56, 1201.

    Article  Google Scholar 

  61. E. Becker, D.R. Richardson, Int. J. Biochem. Cell B, 2001, 33, 1.

    Article  Google Scholar 

  62. I. Fridovich, Annu. Rev. Biochem., 1995, 64, 97.

    Article  Google Scholar 

  63. G. Sachez-Casis, M. Cote, A. Barbeau, Can. J. Neurol. Sci., 1976, 3, 349.

    Google Scholar 

  64. D. Waldvogel, P. van Gelderen, M. Hallett, Ann. Neurol., 1999, 46, 123.

    Article  Google Scholar 

  65. S. Jiralerspong, Y. Liu, L. Montermini, S. Stifani, M. Pandolfo, Neurobiol. Dis., 1997, 4, 103.

    Article  Google Scholar 

  66. E.C. Hirsch, Ann. Neurol., 1992, 32, S88.

    Article  Google Scholar 

  67. P.L. McGeer, S. Itagaki, H. Akiyama, E.G. McGeer, Ann. Neurol., 1988, 24, 574.

    Article  Google Scholar 

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(2007). Investigation of Neurodegenerative Disorders (II). In: Applications of Synchrotron Radiation. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-46427-3_7

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