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Regional Assessment of Liver Disease Progression and Response to Therapy by Multi-time Point m-SLIC Correspondence

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Medical Image Understanding and Analysis (MIUA 2018)

Abstract

Liver disease has reached worryingly high levels worldwide and there is a need for better analysis to monitor progression of disease and response to therapy. Quantitative imaging such as corrected T1 and PDFF can accurately quantify levels of inflammation/fibrosis and fat. In this study we develop a method to assess regional change throughout the liver to characterise disease change. We show that this method is stable in healthy test-retest cases but is able to characterise change in disease in autoimmune hepatitis cases.

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References

  1. Achanta, R., Shaji, A., Smith, K., Lucchi, A., Fua, P., Sãijsstrunk, S.: SLIC superpixels compared to state-of-the-art superpixel methods. IEEE Trans. Pattern Anal. Mach. Intell. 34(11), 2274–2282 (2012)

    Article  Google Scholar 

  2. Banerjee, R., et al.: Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease. J. Hepatol. 60(1), 69–77 (2014)

    Article  Google Scholar 

  3. Heimann, T., Meinzer, H.P.: Statistical shape models for 3D medical image segmentation: a review. Med. Image Anal. 13(4), 543–563 (2009)

    Article  Google Scholar 

  4. Irving, B., et al.: Deep quantitative liver segmentation and vessel exclusion to assist in liver assessment. In: Valdés Hernández, M., González-Castro, V. (eds.) MIUA 2017. CCIS, vol. 723, pp. 663–673. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-60964-5_58

    Chapter  Google Scholar 

  5. Irving, B., et al.: maskSLIC: regional superpixel generation with application to local pathology characterisation in medical images. CoRR abs/1606.09518 (2017). http://arxiv.org/abs/1606.09518

  6. O’Connor, J.P., Rose, C.J., Waterton, J.C., Carano, R.A., Parker, G.J., Jackson, A.: Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome. Clin. Cancer Res. 21(2), 249–257 (2015)

    Article  Google Scholar 

  7. Pavlides, M., et al.: Multiparametric magnetic resonance imaging predicts clinical outcomes in patients with chronic liver disease. J. Hepatol. 64(2), 308–315 (2016)

    Article  Google Scholar 

  8. Wang, F.S., Fan, J.G., Zhang, Z., Gao, B., Wang, H.Y.: The global burden of liver disease: the major impact of China. Hepatology 60(6), 2099–2108 (2014)

    Article  Google Scholar 

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Correspondence to Benjamin Irving .

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Irving, B. et al. (2018). Regional Assessment of Liver Disease Progression and Response to Therapy by Multi-time Point m-SLIC Correspondence. In: Nixon, M., Mahmoodi, S., Zwiggelaar, R. (eds) Medical Image Understanding and Analysis. MIUA 2018. Communications in Computer and Information Science, vol 894. Springer, Cham. https://doi.org/10.1007/978-3-319-95921-4_5

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  • DOI: https://doi.org/10.1007/978-3-319-95921-4_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-95920-7

  • Online ISBN: 978-3-319-95921-4

  • eBook Packages: Computer ScienceComputer Science (R0)

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