Neonatal Infections

1. Front Matter

   Pages i-xi

   PDF

2. Perinatal Infections

   1. Front Matter

      Pages 1-1

      PDF

   2. Early-Onset Sepsis

      • Susan A. Lee

      Pages 3-10

   3. Late-Onset Sepsis

      • Niraj Vora

      Pages 11-20

   4. Necrotizing Enterocolitis

      • Sarah Henen, Jennifer Duchon

      Pages 21-32

   5. Candida

      • Hillary B. Liken, David A. Kaufman

      Pages 33-49

   6. Neonatal Conjunctivitis

      • Karli L. McCoy, Charlene R. Bultmann

      Pages 51-55

   7. Respiratory Viruses in the Neonatal Intensive Care Unit

      • Phillip S. Wozniak

      Pages 57-63

3. Congenital Infections

   1. Front Matter

      Pages 65-65

      PDF

   2. Pathogenesis of Congenital Infections

      • Joseph B. Cantey

      Pages 67-73

   3. Chagas Disease

      • Morven S. Edwards, Kelly K. Stimpert, Susan P. Montgomery

      Pages 75-82

   4. Cytomegalovirus Infection

      • Andrea Ronchi, Lorenza Pugni, Fabio Mosca

      Pages 83-93

   5. Enteroviruses

      • Emily Carroll

      Pages 95-101

   6. Hepatitis B in the Perinatal Period

      • Rebecca A. M. Pierce-Williams, Jeanne S. Sheffield

      Pages 103-109

   7. Hepatitis C and Pregnancy

      • Rebecca A. M. Pierce-Williams, Jeanne S. Sheffield

      Pages 111-118

   8. Neonatal Herpes Simplex Virus Infection

      • Nazia Kabani, David Kimberlin

      Pages 119-126

   9. Management of HIV-Exposed Infants

      • Wei Li A. Koay, Allison L. Agwu

      Pages 127-134

   10. Lymphocytic Choriomeningitis Virus

       • Joseph B. Cantey

       Pages 135-137

   11. Malaria

       • Joseph B. Cantey

       Pages 139-146

   12. Parvovirus

       • Mridula Sunkara

       Pages 147-152

There are approximately 4 million newborns annually in the United States, including 400,000 infants born preterm.  This care occurs in nurseries of all acuity levels, sizes, and regions across the country and is provided by a variety of providers, including pediatricians, family practice doctors, nurse practitioners, and physician assistants.  The most common complication during the newborn period is suspected or proven infection – either those acquired during the delivery itself or before delivery in the womb.  Indeed, 4 of the 8 most commonly-prescribed medications in newborns annually are antibiotics. Therefore, these providers must all be knowledgeable about the clinical presentation, epidemiology, and approach to diagnosis, treatment and prevention of neonatal infections.  However, many of these nurseries do not have convenient access to pediatric infectious disease consultation or support, and would benefit from a convenient reference guide.


This book effectively and succinctly covers the pathophysiology, epidemiology, clinical presentation, approach to diagnosis and treatment, and important aspects of preventative care for the most frequently encountered neonatal and congenital infections.  The first section discusses common neonatal infections (i.e., those acquired during or after delivery), including sepsis, meningitis, pneumonia, and other focal infections.  The second section covers the most frequently encountered congenital infections (i.e., those acquired via the placenta while the fetus is still in-utero).  Finally, the concluding section discusses the basics of infection prevention in the nursery setting, including general principles of infection prevention, how to apply those principles to families, and how to manage a suspected outbreak of infection within a nursery.


This book is a unique contribution to the field. Existing texts such as the AAP Red Book fold neonatal infections in within chapters on a given pathogen, but the information is difficult to find and access quickly.  By covering neonatal and congenital infections thoroughly while still keeping each section clear and concise, this Handbook will be a valuable resource for the busy nursery provider.

• Pathophysiology
• Epidemiology
• Clinical presentation
• Diagnosis
• Prevention
• infectious diseases
• maternal and child health

“As a series of relatively brief chapters describing most aspects of neonatal infectious disease, this book can serve as a quick reference guide to the most common bacterial, viral, and fungal infections in the nursery. … The book is an excellent reference for students, residents, and fellows … . This is a succinct guide to neonatal infections and is much more user friendly for clinicians than the standard comprehensive texts … .” (Jay P. Goldsmith, Doody's Book Reviews, October, 2018)

• University of Texas Health Science Center San Antonio, San Antonio, USA

  Joseph B. Cantey

Dr. Cantey is a board certified neonatalist specializing in infectious diseases and perinatal medicine.  He received his medical degree from the Medical University of South Carolina in 2006 before completing his fellowships in pediatric infectious diseases and neonatal/perinatal medicine at the University of Texas, Southwestern Medical Center.  He has published numerous journal articles and book chapters and is currently an assistant professor at Texas A&M Health Science Center College of Medicine.

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