Skip to main content

Glomerular Disease in the Elderly

  • Reference work entry
  • First Online:
Geriatric Diseases

Abstract

This is a brief review of glomerular disease in the elderly. The incidence of glomerula disease (GD) in the elderly is relatively higher than in young adults. This has been attributed to the increase in malignancies and in the use of a variety of drugs. The histopathological change in the elderly includes extracapillary proliferation, membranoproliferation, membranous nephropathy, focal-segmental glomerulosclerosis, mesangial glomerulonephritis, minimal change disease and diabetic glomerulosclerosis. In the elderly, postinfectious GN may account for a higher proportion in the elderly.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 379.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Abrass CK. Renal biopsy in the elderly Am J Kidney Dis. 2000;35:544–546.

    Article  CAS  PubMed  Google Scholar 

  2. Sabins SG, Antonoiych TT. A study of 500 cases of kidney diseases in the elderly. Geriatr Nephrol Urol. 1993;3: (1)15–22.

    Article  Google Scholar 

  3. Davison AM. Renal disease in the elderly. Nephron. 1998;50:6–16.

    Article  Google Scholar 

  4. Sanchez-Fructuoso A, Macia M, Blanco J, Barrientos A. Glomerular disease in the elderly: incidence and clinicopathologic findings: a 20 year retrospective study. Geriatr Nephrol Urol. 1993;3(2): 65–70.

    Article  Google Scholar 

  5. Prakesh J, Singh AK, Saxena RK. Glomerular diseases in the elderly in India. Int J Urol Nephrol. 2000;353:283–288.

    Google Scholar 

  6. Qian Qi, Nasr SH. Diagnosis and treatment of glomerular diseases in the elderly. Advances in Chronic Kidney Diseases (ACKD). 2014;21(2):228–246.

    Article  Google Scholar 

  7. Rivera F, Lopez-Gomez JM, Perez-Garcia R. Clinicopathologic correlations of renal pathology in Spain. Kid Int. 2004, 66:898–904.

    Article  Google Scholar 

  8. Ali H. Renal disease in the elderly. Postgrad Med. 1996;100:44–51.

    Article  CAS  PubMed  Google Scholar 

  9. Moorthy AV, Zimmerman SW. Renal disease in the elderly: clinicopathological analysis of renal disease in 115 elderly patients. Clin Nephrol. 1980;14(5):223–9.

    CAS  PubMed  Google Scholar 

  10. Falk RJ, Hogan S, Carey TS, Jenntte JC. Clinical course of anti-neutrophil cytoplasmic auto-antibodies associated with glomerulonephritis and systemic vasculitis. Ann Intern Med. 1998;113(9):656–63.10.

    Article  Google Scholar 

  11. Nasr SH, Markowitz GS, Stokes MB, Said SM, Valeri AM, D’Agati VD, et al. Acute postinfectious glomerulonephritis in the modern era: experience with 86 adults and review of the literature. Medicine. 2008;87:21–32.

    Article  PubMed  Google Scholar 

  12. Abrass CK. Chapter 10. Glomerular disease in the elderly. Geriatr Nephrology Curriculum, American Society of Nephrology. 2009.

    Google Scholar 

  13. Ponticelli C, Passerini P, Cresseri D. Primary glomerular diseases in the elderly. Geriatr Nephrol Urol. 1996;6(2):105–112.

    Article  Google Scholar 

  14. Johnston PA, Brown JS, Davison AM. The nephrotic syndrome in the elderly: 8ynchr-pathological correlations in 317 patients. Geriatr Nephrol. 1992;2(2):85–99.

    Article  Google Scholar 

  15. Cameron JS. Nephrotic syndrome in the elderly. Semin Nephrol. 1996;16(4):319–29.

    CAS  PubMed  Google Scholar 

  16. Shin JH, Pyo HJ, Kwon Y, Chang MK, Kim HK, Win NH, et al. Renal biopsy in elderly patients: Clinicopathological correlation in 117 Korean patients. Clin Nephrol. 2001;56(1):19–26.

    CAS  PubMed  Google Scholar 

  17. Uezono S, Hara S, Sato Y, Komatsu H, Ikeda N, Shimao Y, et al. Renal biopsy in elderly patients: a clinicopathological analysis. Renal Failure. 2006;28:549–555.

    Article  PubMed  Google Scholar 

  18. Nair R, Bell JM, Walker PD. Renal biopsy inpatients aged 80 years and older. Am J Kidney Dis. 2004;44:618–626.

    Article  PubMed  Google Scholar 

  19. Fliser D, Franek E, Joest M, Block S, Mutschler E, Ritz E. renal function in the elderly: impact of hypertension and cardiac function. Kidney Iternstional. https://doi.org/10.1038/ki.1997.163.

  20. Stephany B. Primary glomerular diseases. Cleveland clinic. http://www.clevelandclinicmeded.com/medicalpibs/diseasemanagement/nephrology/primary-glomerular-diseases/ accessed 16 January 2017.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Nagaratnam, N., Nagaratnam, K., Cheuk, G. (2018). Glomerular Disease in the Elderly. In: Geriatric Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-33434-9_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-33434-9_30

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33433-2

  • Online ISBN: 978-3-319-33434-9

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics