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Renal Sinus Lipomatosis

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  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Synonyms

Renal replacement lipomatosis

Definition

A condition of benign proliferation of adipose tissue within renal sinus, hilum, and perirenal space, replacing the renal parenchyma. Renal replacement lipomatosis is characterized by complete replacement of the kidney by adipose tissue, with varying degrees of fibrosis (Ratkal et al. 2015).

Clinical Features

  • Incidence

    Rare.

  • Age

    Any age.

  • Sex

    Both male and female.

  • Site

    Renal sinus, hilum, and perirenal space.

  • Treatment

    None.

  • Outcome

    Benign.

Macroscopy

The kidney is usually enlarged and presents with a gross fibro-fatty appearance and renal cortical atrophy. It is usually associated with chronic pyelonephritis, renal lithiasis, and hydronephrosis. The shape of the kidney is always preserved (Rha et al. 2004).

Microscopy

The renal cortex is extremely atrophied, with varying degrees of hydronephrosis or pyonephrosis as well as acute and chronic pyelonephritic changes. There is marked proliferation of adipose tissue in the renal sinus, with...

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References and Further Reading

  • Ratkal, V., Chawla, A., Mishra, D. K., & Krishna, S. (2015). Renal replacement lipomatosis of the right kidney. BML Case Reports, 6, 2015.

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  • Rha, S. E., Byun, J. Y., Jung, S. E., Oh, S. N., Choi, Y. J., Lee, A., & Lee, J. M. (2004). The renal sinus: Pathologic spectrum and multimodality imaging approach. Radiographics, 24(Suppl 1), S117–S131.

    Article  Google Scholar 

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Correspondence to Rodolfo Montironi .

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Cimadamore, A., Montironi, R. (2019). Renal Sinus Lipomatosis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4927-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4927-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

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