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Heterogeneity of Stem Cells in the Hippocampus

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Stem Cells Heterogeneity in Different Organs

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1169))

Abstract

The discovery of neural stem cells in the adult mammalian hippocampus has attracted attention and controversy, which both continue to this day. Hippocampal neural stem cells and their immediate progeny, amplifying neuroprogenitor cells, give rise to neurons and astrocytes in the region. Envisioned as possible key for tissue regeneration, whether mobilized endogenously or transplanted exogenously, neural stem cells have been in the eye of both public and science over the course of the past 20 years. These cells are a heterogeneous population, and here, we review different aspects of their heterogeneity from morphology to metabolism and response to different stimuli.

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Authors and Affiliations

  1. Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, TX, USA

    Mehmet Tosun, Fatih Semerci & Mirjana Maletic-Savatic

  2. Department of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, USA

    Mehmet Tosun, Fatih Semerci & Mirjana Maletic-Savatic

  3. Department of Neuroscience, Program in Developmental Biology and Quantitative Computational Biology Program, Baylor College of Medicine, Houston, TX, USA

    Mirjana Maletic-Savatic

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  1. Department of Pathology, Federal University of Minas Gerais, Department of Radiology, Columbia University Medical Center, New York, NY, USA, Belo Horizonte, Minas Gerais, Brazil

    Alexander Birbrair

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Tosun, M., Semerci, F., Maletic-Savatic, M. (2019). Heterogeneity of Stem Cells in the Hippocampus. In: Birbrair, A. (eds) Stem Cells Heterogeneity in Different Organs. Advances in Experimental Medicine and Biology, vol 1169. Springer, Cham. https://doi.org/10.1007/978-3-030-24108-7_2

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