Intrahepatic Cholangiocarcinoma

1. Front Matter

   Pages i-xi

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2. Epidemiology and Risk Factors

   • Riham Katkhuda, Yun Shin Chun

   Pages 1-10

3. Clinical Presentation and Diagnosis

   • Arezou Abbasi, Amir A. Rahnemai-Azar, Sean M. Ronnekleiv-Kelly, Daniel E. Abbott, Sharon M. Weber

   Pages 11-20

4. Staging and Prognosis

   • Janelle F. Rekman, Flavio G. Rocha

   Pages 21-51

5. Imaging

   • Pegah Khoshpouri, Timothy M. Pawlik, Ihab R. Kamel

   Pages 53-66

6. Surgical Treatment

   • Georgios Antonios Margonis, George A. Poultsides

   Pages 67-83

7. Management of the Nodal Basin

   • Alfredo Guglielmi, Fabio Bagante, Andrea Ruzzenente, Tommaso Campagnaro, Simone Conci, Calogero Iacono

   Pages 85-94

8. Pathologic Assessment

   • Benjamin J. Swanson

   Pages 95-105

9. Systemic Therapy

   • Ning Jin, Laith Abushahin

   Pages 107-121

10. Percutaneous Ablation

    • Guojun Qian, Jinglei Zhang, Feng Shen

    Pages 123-134

11. Transarterial Therapies

    • Susan Shamimi-Noori, Michael C. Soulen

    Pages 135-150

12. Radiotherapy

    • Florence K. Keane, Theodore S. Hong

    Pages 151-165

13. Molecular Pathogenesis: From Inflammation and Cholestasis to a Microenvironment-Driven Tumor

    • Eleonora Milani, Mario Strazzabosco, Luca Fabris, Massimiliano Cadamuro

    Pages 167-182

14. Clinical Trials and Novel/Emerging Treatment

    • Jonathan D. Mizrahi, Reham Abdel-Wahab, Milind Javle

    Pages 183-208

15. Back Matter

    Pages 209-215

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This book provides a comprehensive review of the epidemiology, molecular pathogenesis, diagnosis and treatment of intrahepatic cholangiocarcinoma (ICC).  It brings together an impressive group of international experts in cholangiocarcinoma research and clinical care.  The book was organized and written to aid the clinician’s understanding of emerging research in cholangiocarcinoma and its application to the clinical care of patients with ICC. Each chapter details the scientific evidence to support clinical decisions that are needed to care for these complex patients.  Focused chapters detail the epidemiology, diagnostic evaluation, as well as staging and prognosis of this disease. In addition to dedicated chapters on surgical management of ICC, a broad emphasis on locoregional therapies, including percutaneous ablation and transarterial therapies, is included. An up-to-date overview of the molecular pathogenesis and pathological assessment of ICC is detailed prior to chapters focusing on systemic chemotherapy and emerging novel therapy options.

Intrahepatic Cholangiocarcinoma is not only an invaluable resource for many as they seek to provide the best multidisciplinary cancer care to patients with ICC, but also an opportunity to identify new avenues of scientific discovery that lead to significant advances in the diagnosis and management of ICC.

• Molecular Pathogenesis
• Nodal Basin
• Systemic Therapy
• ICC
• Intra-arterial Therapy
• surgical oncology

• Wexner Medical Center, The Ohio State University, Columbus, USA

  Timothy M. Pawlik, Jordan M. Cloyd, Mary Dillhoff

Timothy M. Pawlik

The Ohio State University, Wexner Medical Center

Columbus, OH

USA

 

Jordan M. Cloyd

The Ohio State University, Wexner Medical Center

Columbus, OH

USA

 

Mary Dillhoff

The Ohio State University, Wexner Medical Center

Columbus, OH

USA

 

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